中性粒细胞减少症患者脓毒症的治疗。

Q4 Medicine Acta Medica Croatica Pub Date : 2015-09-01
V Zatezalo, N J Gredelj Šimec
{"title":"中性粒细胞减少症患者脓毒症的治疗。","authors":"V Zatezalo,&nbsp;N J Gredelj Šimec","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Febrile neutropenia is a common and potentially fatal complication of intense cytotoxic therapy, which makes it the main cause\nof non-relapse mortality in patients with hematologic malignancies. Some of the patients are at risk of specific infections due to\nunderlying disease of previous treatment regimens. Considering that most febrile neutropenic patients can be diagnosed with\nsepsis, diagnosis and treatment should be treated as septic. It is important to recognize patients at high risk since the incidence\nof sepsis in neutropenic patients can be significantly reduced using antimicrobial prophylaxis and granulocyte growth factors.\nOnce sepsis occurs, prompt treatment according to guidelines, individualized based on the specific problems of each patient,\nand microbiological situation can significantly reduce mortality and morbidity.</p>","PeriodicalId":35756,"journal":{"name":"Acta Medica Croatica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[TREATMENT OF SEPSIS IN NEUTROPENIC PATIENTS].\",\"authors\":\"V Zatezalo,&nbsp;N J Gredelj Šimec\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Febrile neutropenia is a common and potentially fatal complication of intense cytotoxic therapy, which makes it the main cause\\nof non-relapse mortality in patients with hematologic malignancies. Some of the patients are at risk of specific infections due to\\nunderlying disease of previous treatment regimens. Considering that most febrile neutropenic patients can be diagnosed with\\nsepsis, diagnosis and treatment should be treated as septic. It is important to recognize patients at high risk since the incidence\\nof sepsis in neutropenic patients can be significantly reduced using antimicrobial prophylaxis and granulocyte growth factors.\\nOnce sepsis occurs, prompt treatment according to guidelines, individualized based on the specific problems of each patient,\\nand microbiological situation can significantly reduce mortality and morbidity.</p>\",\"PeriodicalId\":35756,\"journal\":{\"name\":\"Acta Medica Croatica\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Medica Croatica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Medica Croatica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

发热性中性粒细胞减少症是高强度细胞毒治疗中一种常见且可能致命的并发症,是恶性血液病患者非复发性死亡的主要原因。一些患者由于先前治疗方案的潜在疾病而有特定感染的风险。考虑到大多数发热性中性粒细胞减少患者可诊断为脓毒症,诊断和治疗应按脓毒症处理。重要的是要认识到高危患者,因为中性粒细胞减少患者的败血症发生率可以通过抗菌预防和粒细胞生长因子显著降低。一旦发生脓毒症,及时按照指南进行治疗,根据每位患者的具体问题和微生物情况进行个体化治疗,可显著降低死亡率和发病率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
[TREATMENT OF SEPSIS IN NEUTROPENIC PATIENTS].

Febrile neutropenia is a common and potentially fatal complication of intense cytotoxic therapy, which makes it the main cause of non-relapse mortality in patients with hematologic malignancies. Some of the patients are at risk of specific infections due to underlying disease of previous treatment regimens. Considering that most febrile neutropenic patients can be diagnosed with sepsis, diagnosis and treatment should be treated as septic. It is important to recognize patients at high risk since the incidence of sepsis in neutropenic patients can be significantly reduced using antimicrobial prophylaxis and granulocyte growth factors. Once sepsis occurs, prompt treatment according to guidelines, individualized based on the specific problems of each patient, and microbiological situation can significantly reduce mortality and morbidity.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Acta Medica Croatica
Acta Medica Croatica Medicine-Medicine (all)
自引率
0.00%
发文量
0
期刊介绍: ACTA MEDICA CROATICA publishes original contributions to medical sciences, that have not been previously published. All manuscripts should be written in English.
期刊最新文献
[URATE AS A POTENTIAL RISK FACTOR OF CARDIOVASCULAR AND RENAL DISEASES]. [ADRENOCORTICAL CARCINOMA]. [GLYCEMIC CONTROL IN DIABETES MELLITUS PATIENTS WITH CHRONIC KIDNEY DISEASE – HOW TO CHOOSE HYPOGLYCEMIC AGENT]? [DIET CHARACTERISTICS IN PATIENTS WITH CHRONIC KIDNEY DISEASE]. [CARDIORENAL SYNDROME: CLINICAL FEATURES, EARLY DIAGNOSIS AND TREATMENT AT FAMILY MEDICINE].
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1