Mackenzie Hagan, Mi Zhou, Muhammad Ashraf, Il-Man Kim, Huabo Su, Neal L Weintraub, Yaoliang Tang
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Long noncoding RNAs and their roles in skeletal muscle fate determination.
Myogenic fate determination is important in skeletal muscle development, growth and repair. A variety of factors regulate myogenic cell determination via transcriptional and non-transcriptional mechanisms. Amongst these factors, long noncoding RNAs (lncRNAs) have gained considerable attention for their important roles in regulating myogenic differentiation and function. Many classes of lncRNAs have been discovered; various lncRNAs have been implicated in the regulation of myogenic cell fate determination and are the subject of this brief review.
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