SLE治疗过程中霉酚酸酯引起的后部可逆性脑病综合征(PRES):一例报告和回顾

IF 1.4 Q4 IMMUNOLOGY American journal of clinical and experimental immunology Pub Date : 2018-02-05 eCollection Date: 2018-01-01
Lei Zhang, Jian Xu
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引用次数: 0

摘要

后部可逆性脑病综合征(PRES)是一种罕见的与系统性红斑狼疮相关的临床症状,其特征为癫痫发作、头痛和精神状态改变。病理生理包括继发于高血压和内皮损伤的皮质下血管源性水肿。通过停用药物、严格控制血压和治疗基础疾病,PRES是可逆的。我们报告一例狼疮性肾炎患者在服用霉酚酸盐后出现PRES。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Posterior reversible encephalopathy syndrome (PRES) attributed to mycophenolate mofetil during the management of SLE: a case report and review.

Posterior reversible encephalopathy syndrome (PRES) is a rare clinical entity associated with systemic lupus erythematosus which characterized by seizure, headache, and altered mental status. The pathophysiology involves subcortical vasogenic edema secondary to hypertension and endothelial damage. PRES is reversible with withdrawal of the offending agent, strict blood pressure control, and treating the underlying disease. We report present here a patient with lupus nephritis who developed PRES following mycophenolate administration.

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