北方邦坎普尔人口口腔癌医院患病率评估

Q3 Pharmacology, Toxicology and Pharmaceutics Journal of Experimental Therapeutics and Oncology Pub Date : 2018-05-01
Amrita Raj, Gayathri Ramesh, Sunita Pathak
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引用次数: 0

摘要

背景:口腔癌的发病率取决于定性和定量因素,其中有吸烟和咀嚼烟草习惯的患者口腔癌的发病率是无习惯患者的8.4倍。目的:了解坎普尔市住院人群口腔癌患病率,分析其与年龄、性别和吸烟习惯的关系。材料与方法:检索2007年1月至2016年12月组织病理学诊断的320例鳞状细胞癌病例资料,结合年龄、性别、部位、生活习惯、组织病理类型等变量进行回顾性研究。结果:30 ~ 39岁年龄组71例(22.18%),30岁以下年龄组60例(18.75%)。有吸烟习惯者中,嚼烟者135人(42.18%),吸烟流行者48人(15%)。以男性37例(15.22%)居多。在男性(44.03%)和女性(48.05%)中,牙龈-颊沟是最常见的部位。最不常见的部位为唇部,仅有10例(3.12%)。高分化鳞状细胞癌在男性和女性中都很常见,分别为155例(63.78%)和47例(61.03%)。低分化鳞状细胞癌男性仅4例(1.64%)。结论:早期发现这些口腔癌有助于适当的临床管理和监测。此外,提高口腔癌的发病率、死亡率和生存率需要针对社会、牙医、社区和个人的多层结构方法。
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Assessment of hospital based prevalence of oral cancer among population of Kanpur, Uttar Pradesh.

Background: Oral cancer incidence depends on both qualitative and quantitative factors wherein the incidence of oral cancer in patients with smoking and tobacco chewing habit is 8.4 times higher than that of patients with no habit.

Aim: To understand about the prevalence of oral cancer in population of Kanpur reported to the hospital and analyse the association with age, gender and tobacco habit.

Material and method: All 320 cases of Squamous cell carcinoma diagnosed histopathologically, since January 2007 to December 2016, were retrieved from the archives and a retrospective study was conducted along with association with the variables such as age, gender, site, habit and histopathological type.

Results: A total of 71 cases were reported in the age group of 30-39 (22.18%) and 60 cases (18.75%) were seen to be below 30yrs. Among individuals with habit, 135 (42.18%) were tobacco chewers and smoking was prevalent in about 48 (15%). The prevalence was more in males 37 (15.22%). Amongst both males (44.03%) and females (48.05%) gingivo-buccal sulcus was the most common site. The least common site was seen to be lip with only 10 (3.12%) patients. Well differentiated squamous cell carcinoma was common in both males and females with 155 (63.78%) and 47 (61.03%) respectively. Poorly differentiated squamous cell carcinoma was only reported in 4(1.64%) males.

Conclusion: Early detection of these oral cancers will enable appropriate clinical management and monitoring. Moreover, improving the incidence, mortality, and survival rates of oral cancer requires a multi-tier structural approach that targets society, dentists, communities, and the individual.

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