[黄芩根的化学成分]。

中药材 Pub Date : 2016-08-01
Kun Yu, Yi Peng, Zhi-xing Qing, Peng Yang, Zi Zuo, Jian-guo Zeng
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引用次数: 0

摘要

目的:研究苦参根的化学成分。方法:采用硅胶、重结晶、半制备高效液相色谱等方法对化合物进行分离纯化,采用理化性质、质谱、核磁共振等方法对化合物结构进行鉴定。结果:分离得到7个化合物,鉴定为6-氰基二氢切红素(1)、6-氰基二氢切红素(2)、二氢切红素(3)、6-甲氧基去切红素(4)、二氢血碱(5)、6-酰基二氢血碱(6)和豆头甾醇(7)。结论:化合物1、2为天然新化合物,化合物4为首次从麻瓜属植物中分离得到。
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[Chemical Constituents from the Roots of Macleaya cordata].

Objective: To investigate the chemical constituents from the roots of Macleaya cordata.

Methods: The compounds were isolated and purified by silica gel,recrystallization and semi-preparative HPLC, their structures were eclucidated by physicochemistry properties, MS and NMR.

Results: Seven compounds were isolated and identified as 6-cyanodihydrochelerythrine (1),6-cyanodihydrochelilutine (2),dihydrochelirubine (3),6-methoxynorchelerythrine (4),dihydrosanguinarine (5),6-actonyldihydrosanguinarine (6) and stigmasterol (7).

Conclusion: Compounds 1,2 are new natural compounds and compound 4 is obtained from Macleaya cordata for the first time.

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期刊介绍: "Chinese Materia Medica" magazine was founded in 1978. It is a national-level academic journal of Chinese medicine science and technology approved by the State Science and Technology Commission and the Press and Publication Administration for public distribution at home and abroad. It is sponsored by the Chinese Materia Medica Information Center of the State Food and Drug Administration and is publicly distributed at home and abroad. It mainly reports on new technologies, new methods and new achievements in the production, scientific research and business management of Chinese medicine, and serves to promote the production and scientific and technological development of Chinese medicine, improve the output and quality of Chinese medicine, improve business management, and prosper the Chinese medicine industry.
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