杜仲的化学成分。

中药材 Pub Date : 2016-09-01

Kun Li, Zhi-you Hao, Cui-li Zhang, Yan-jun Sun, Hui Chen

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引用次数: 0

摘要

目的:研究杜仲树皮的化学成分。方法:杜仲皮经95%乙醇回流提取，乙酸乙酯部分经硅胶、Sephadex LH-20、ODS C18等色谱法分离纯化。用现代光谱方法对分离化合物的结构进行了分析。结果:从杜仲中分离到5种木脂素和3种苯丙素，分别为环榄素(1)、(7R, 8S, 8' r)- 4,9,4 '， 8'-四羟基- 3,3 '-二甲基氧基- 7,9 '-单环氧木脂素(2)、红愈创木酚基-甘油-β-松柏醛醚(3)、蒎烯醇(4)、8-羟基氨基树脂醇(5)、c - veratroyl乙二醇(6)、β-羟基-3-甲氧基-4-羟基苯乙酮(7)和3-羟基-4-甲氧基肉桂醛(8)。其中化合物5 ~ 8为首次从该植物中分离得到。

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[Chemical Constituents from Eucommia ulmoides].

Objective: To investigate the chemical constituents from the barks of Eucommia ulmoides.

Methods: After the reflux extraction of the barks of Eucommia ulmoides with 95% ethanol, and the ethyl acetate part was separated and purified by chromatographic methods, such as silica gel, Sephadex LH-20, and ODS C18. The structures of isolated compounds were elucidated with modern spectral methods.

Results: Five lignanoids and three phenylpropanoids were isolated from Eucommia ulmoieds, which were confirmed as cycloolivil (1), (7R, 8S, 8'R)-4, 9, 4', 8'-tetrahydroxy-3, 3'-dimethyoxyl-7, 9'-monoepoxy lignan (2), erythro-guaiacyl-glycerol-β-coniferyl aldehyde ether (3), pinonesinol (4), 8-hydroxypinoresinol (5), C-veratroylglycol (6), β-hydroxyl-3-methoxyl-4-hydroxyacetophenone (7) and 3-hydroxy-4-methoxycinnamaladehyde (8).

Conclusion: Compounds 5–8 are isolated from this plant for the first time.

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来源期刊

中药材

自引率

0.00%

发文量

11364

期刊介绍： "Chinese Materia Medica" magazine was founded in 1978. It is a national-level academic journal of Chinese medicine science and technology approved by the State Science and Technology Commission and the Press and Publication Administration for public distribution at home and abroad. It is sponsored by the Chinese Materia Medica Information Center of the State Food and Drug Administration and is publicly distributed at home and abroad. It mainly reports on new technologies, new methods and new achievements in the production, scientific research and business management of Chinese medicine, and serves to promote the production and scientific and technological development of Chinese medicine, improve the output and quality of Chinese medicine, improve business management, and prosper the Chinese medicine industry.