马的人畜共患病毒性疾病及其对人类和动物健康的影响。

Balvinder Kumar, Anju Manuja, B R Gulati, Nitin Virmani, B N Tripathi
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引用次数: 41

摘要

引言:动物传染病是指可以直接或间接从动物传播给人类的传染病,反之亦然。这些疾病可能由一系列生物体引起,包括细菌、寄生虫、病毒和真菌。病毒性疾病具有高度传染性,能够引起流行病,埃博拉、中东呼吸综合征、西尼罗河、严重急性呼吸系统综合征、尼帕、亨德拉、禽流感和猪流感等疾病的爆发就是明证。扩散:许多影响马的病毒也是重要的人类病原体。东部马脑炎(EEE)、西部马脑炎(WEE)和委内瑞拉马脑炎(VEE)等疾病具有高度传染性,可通过气溶胶传播。委内瑞拉和哥伦比亚连续发生大量马和人VEE致命脑炎病例。水泡性口腔炎(VS)在北美的马中流行,具有引起儿童脑炎的人畜共患潜力。亨德拉病毒(HeV)会导致人和马的呼吸系统和神经系统疾病以及死亡。自1994年首次爆发以来,澳大利亚已报告了53起疾病事件。近年来,西尼罗河热已经蔓延到各大洲许多新的地区。在非洲、欧洲、南亚、大洋洲和北美洲都有描述。日本脑炎已将范围从亚洲扩展到西太平洋地区,包括印尼群岛东部、巴布亚新几内亚和澳大利亚。狂犬病在马身上很罕见,但仍然是一种致命的公共卫生问题。马流感在历史上并不影响人类,但许多科学家的观点不一。本文阐述了具有人畜共患重要性的马病毒性疾病及其对动物和人类健康的影响。结论:马病毒性疾病虽然局限于特定的地理区域,但对马和人类健康有着巨大的影响。西尼罗河热、亨德拉、VS、VEE、EEE、JE、狂犬病等疾病具有在人类中传播的潜力和致病能力。马流感在历史上并不影响人类,但一些实验和观察证据表明,H3N8流感病毒已经感染了人类。尽管我们试图了解介导疾病传播的媒介宿主病原体的复杂性,但还不可能对疾病出现的影响程度做出笼统的预测。需要有针对性的多学科努力来了解人畜共患病的风险因素,并采取必要的干预措施来控制它。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Zoonotic Viral Diseases of Equines and Their Impact on Human and Animal Health.

Introduction: Zoonotic diseases are the infectious diseases that can be transmitted to human beings and vice versa from animals either directly or indirectly. These diseases can be caused by a range of organisms including bacteria, parasites, viruses and fungi. Viral diseases are highly infectious and capable of causing pandemics as evidenced by outbreaks of diseases like Ebola, Middle East Respiratory Syndrome, West Nile, SARS-Corona, Nipah, Hendra, Avian influenza and Swine influenza.

Expalantion: Many viruses affecting equines are also important human pathogens. Diseases like Eastern equine encephalitis (EEE), Western equine encephalitis (WEE), and Venezuelan-equine encephalitis (VEE) are highly infectious and can be disseminated as aerosols. A large number of horses and human cases of VEE with fatal encephalitis have continuously occurred in Venezuela and Colombia. Vesicular stomatitis (VS) is prevalent in horses in North America and has zoonotic potential causing encephalitis in children. Hendra virus (HeV) causes respiratory and neurological disease and death in man and horses. Since its first outbreak in 1994, 53 disease incidents have been reported in Australia. West Nile fever has spread to many newer territories across continents during recent years.It has been described in Africa, Europe, South Asia, Oceania and North America. Japanese encephalitis has expanded horizons from Asia to western Pacific region including the eastern Indonesian archipelago, Papua New Guinea and Australia. Rabies is rare in horses but still a public health concern being a fatal disease. Equine influenza is historically not known to affect humans but many scientists have mixed opinions. Equine viral diseases of zoonotic importance and their impact on animal and human health have been elaborated in this article.

Conclusion: Equine viral diseases though restricted to certain geographical areas have huge impact on equine and human health. Diseases like West Nile fever, Hendra, VS, VEE, EEE, JE, Rabies have the potential for spread and ability to cause disease in human. Equine influenza is historically not known to affect humans but some experimental and observational evidence show that H3N8 influenza virus has infected man. Despite our pursuit of understanding the complexity of the vector-host-pathogen mediating disease transmission, it is not possible to make generalized predictions concerning the degree of impact of disease emergence. A targeted, multidisciplinary effort is required to understand the risk factors for zoonosis and apply the interventions necessary to control it.

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