微囊藻毒素的细菌生物降解和解毒过程对环境健康的重要性。

IF 6.4 2区 医学 Q1 ENVIRONMENTAL SCIENCES Journal of Toxicology and Environmental Health-Part B-Critical Reviews Pub Date : 2018-01-01 Epub Date: 2018-10-29 DOI:10.1080/10937404.2018.1532701
Isaac Yaw Massey, Xian Zhang, Fei Yang
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引用次数: 40

摘要

微囊藻毒素(MC)是报道最多的蓝藻有害藻华毒素,主要存在于一些淡水属物种中,对人类和动物健康构成严重威胁。为了减少与MC接触有关的健康风险,必须清除在饮用和娱乐水体中发现的这些毒素。由于物理和化学水处理方法在完全降解MC方面效率低下,寻找有效解毒MC的替代方法已成为全球研究的热点。本综述的目的是提供目前的经济有效的生物处理方法,利用细菌降解MC而不产生有害副产物。此外,还介绍并比较了mc降解过程中涉及mlr基因簇编码蛋白、中间产物和菌株/菌群效率的分解代谢途径。
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Importance of bacterial biodegradation and detoxification processes of microcystins for environmental health.

Microcystins (MC) the most frequently reported cyanobacterial harmful algal bloom toxins primarily found in some species of freshwater genera pose a serious threat to human and animal health. To reduce health risks associated with MC exposure it is important to remove these toxins found in drinking and recreational waterbodies. Since the physical and chemical water treatment methods are inefficient in completely degrading MC, alternative approaches to effectively detoxify MC have become the focus of global research. The aim of this review was to provide the current approach to cost-effective biological treatment methods which utilize bacteria to degrade MC without generation of harmful by-products. In addition, the catabolic pathways involved in MC-degradation involving proteins encoded mlr gene cluster, intermediate products and efficiencies of bacteria strain/bacteria community are presented and compared.

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来源期刊
CiteScore
13.80
自引率
6.90%
发文量
13
审稿时长
>24 weeks
期刊介绍: "Journal of Toxicology and Environmental Health: Part B - Critical Reviews" is an academic journal published by Taylor & Francis, focusing on the critical examination of research in the areas of environmental exposure and population health. With an ISSN identifier of 1093-7404, this journal has established itself as a significant source of scholarly content in the field of toxicology and environmental health. Since its inception, the journal has published over 424 articles that have garnered 35,097 citations, reflecting its impact and relevance in the scientific community. Known for its comprehensive reviews, the journal also goes by the names "Critical Reviews" and "Journal of Toxicology & Environmental Health, Part B, Critical Reviews." The journal's mission is to provide a platform for in-depth analysis and critical discussion of the latest findings in toxicology, environmental health, and related disciplines. By doing so, it contributes to the advancement of knowledge and understanding of the complex interactions between environmental factors and human health, aiding in the development of strategies to protect and improve public health.
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