小胸骨切开vs全胸骨切开主动脉瓣置换术:单中心经验。

Patrícia M Castro, Francisca A Saraiva, Rui J Cerqueira, Soraia Moreira, Mário J Amorim, Adelino F Leite-Moreira, Filipe Macedo
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引用次数: 0

摘要

背景:全胸骨切开术是外科主动脉瓣置换术(AVR)的金标准入路。然而,创伤性较小的潜在优势促进了所谓的微创手术的发展,其中包括上部微型胸骨切开术(MS)。目的:通过MS和FS比较AVR术后即刻临床效果和中期死亡率。方法:单中心回顾性研究,纳入2011年1月1日至2017年7月31日期间通过MS接受孤立AVR的所有患者。然后将这些患者与通过FS进行相同手术的患者以及进行MS手术的相同外科医生进行匹配,对变量年龄,性别,体重指数和糖尿病进行粗略的精确匹配。随后对各组进行特征描述,并通过Qui- squared和Mann-Whitney检验比较术后结果,并通过Kaplan-Meier曲线比较中期死亡率。结果:共纳入82例患者,每组41例。MS组主动脉交叉夹持时间[78分钟对63分钟,p=0.001]和体外循环时间[107分钟对90分钟,p=0.002]明显长于FS组。虽然没有达到统计学上的显著差异,但MS组在手术中需要输注红细胞的患者比例较小(39.0%比53.7%,p=0.184)。在机械通气、肌力支持、吗啡输注、重症监护病房住院时间和新发房颤发生率方面也发现了类似的结果。MS后6年累积生存率为86.7%,FS后为88.5% (p=0.650)。结论:通过MS进行主动脉瓣置换术似乎是金标准FS的一种安全选择。
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Mini-sternotomy versus full sternotomy aortic valve replacement: a single-centre experience.

Background: full sternotomy (FS) is the gold standard approach to perform surgical aortic valve replacement (AVR). However, potential advantages of a less traumatic approach fomented the development of so-called minimally invasive procedures, which include upper mini-sternotomy (MS).

Objective: to compare immediate postoperative clinical results and mid-term mortality after AVR through MS and FS.

Methods: single-centre retrospective study including all patients who underwent isolated AVR through MS between January 1, 2011 and July 31, 2017. These were then matched with patients who underwent the same procedure through FS and by the same surgeons who performed MS, using coarsened exact matching for the variables age, gender, body mass index and diabetes mellitus. Groups were later characterized and compared regarding postoperative results using Qui- -squared and Mann-Whitney tests and regarding mid-term mortality through Kaplan-Meier curves.

Results: we included 82 patients (n=41 in each group). Aortic cross clamp [78 vs. 63 minutes, p=0.001] and cardiopulmonary bypass times [107 vs. 90 minutes, p=0.002] were significantly longer in the MS group vs. FS group, respectively. Although without reaching statistical significant difference, a smaller percentage of patients from the MS group required red blood cells transfusions during surgery (39.0% vs. 53.7%, p=0.184). Similar results were found regarding mechanical ventilation, inotropic support, morphine infusion, intensive care unit length of stay and incidence of de novo atrial fibrillation. Cumulative survival at 6 years was 86.7% after MS and 88.5% after FS (p=0.650).

Conclusions: Aortic valve replacement through MS seems to be a safe alternative to the gold standard FS.

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