增加了PET在亚急性脑病和小细胞肺癌患者中的诊断效用。

Pub Date : 2017-07-01 Epub Date: 2017-07-14 DOI:10.2217/lmt-2016-0020

Anjali Gera, David Olayinka Kamson, Victoria M Villaflor, Rimas V Lukas

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摘要

副肿瘤神经系统疾病(PND)的诊断综合了临床表现(包括与癌症诊断的时间关系)，检测肿瘤神经抗体和排除其他原因。pnd的主要脑成像是MRI。使用放射性示踪剂18f -氟脱氧葡萄糖(FDG)的PET在脑评估中的作用也越来越得到认可。我们描述了一位67岁的女性，50年的吸烟史和小细胞肺癌发展为亚急性脑病，MRI和PET异常确定副肿瘤脑炎。PET可作为诊断部分PND患者的常规工具的补充。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Added diagnostic utility of PET in a patient with subacute encephalopathy and small-cell lung cancer.

Diagnosis of paraneoplastic neurologic disorder (PND) synthesizes the clinical picture (including the temporal relationship to the cancer diagnosis), detection of onconeural antibodies and exclusion of alternative causes. The mainstay of brain imaging of PNDs is MRI. There is also an increasingly recognized role of PET using radiotracer ¹⁸F-Fluorodeoxyglucose (FDG) in the evaluation of the brain. We describe a 67-year-old female with a 50-year smoking history and small-cell lung cancer developing subacute encephalopathy with MRI and PET abnormalities identifying paraneoplastic encephalitis. PET may complement conventional tools in diagnosing a subset of patients with PND.

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