【液体活检在肿瘤分子诊断中的临床应用】。

Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2016-10-01

Mamoru Kubota

{"title":"【液体活检在肿瘤分子诊断中的临床应用】。","authors":"Mamoru Kubota","doi":"","DOIUrl":null,"url":null,"abstract":"\"Liquid biopsy\" is one of the hottest topics in the cancer molecular diagnostics field because of its potential to replace conventional tissue biopsy. \"BEAMing\" is one of the digital PCR platform technologies for liquid biopsy samples, and it features a high enough sensitivity to detect a very low concentration of mutation frag- ments in circulating tumor DNA from the plasma of cancer patients. In this article, some of the promising clinical applications of BEAMing technology and its future possibilities as an advanced cancer diagnostic will be briefly summarized. [Review].","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":"64 10","pages":"1156-1162"},"PeriodicalIF":0.0000,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Clinical Application of Cancer Molecular Diagnostics with Liquid Biopsy].\",\"authors\":\"Mamoru Kubota\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\\"Liquid biopsy\\\" is one of the hottest topics in the cancer molecular diagnostics field because of its potential to replace conventional tissue biopsy. \\\"BEAMing\\\" is one of the digital PCR platform technologies for liquid biopsy samples, and it features a high enough sensitivity to detect a very low concentration of mutation frag- ments in circulating tumor DNA from the plasma of cancer patients. In this article, some of the promising clinical applications of BEAMing technology and its future possibilities as an advanced cancer diagnostic will be briefly summarized. [Review].\",\"PeriodicalId\":21457,\"journal\":{\"name\":\"Rinsho byori. The Japanese journal of clinical pathology\",\"volume\":\"64 10\",\"pages\":\"1156-1162\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rinsho byori. The Japanese journal of clinical pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rinsho byori. The Japanese journal of clinical pathology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

“液体活检”是癌症分子诊断领域最热门的话题之一，因为它有可能取代传统的组织活检。“BEAMing”是液体活检样本的数字PCR平台技术之一，它具有足够高的灵敏度，可以检测癌症患者血浆中循环肿瘤DNA中极低浓度的突变片段。在本文中，简要总结了一些有前景的临床应用，以及它作为晚期癌症诊断的未来可能性。(审查)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

微信好友朋友圈 QQ好友复制链接

本刊更多论文

[Clinical Application of Cancer Molecular Diagnostics with Liquid Biopsy].

"Liquid biopsy" is one of the hottest topics in the cancer molecular diagnostics field because of its potential to replace conventional tissue biopsy. "BEAMing" is one of the digital PCR platform technologies for liquid biopsy samples, and it features a high enough sensitivity to detect a very low concentration of mutation frag- ments in circulating tumor DNA from the plasma of cancer patients. In this article, some of the promising clinical applications of BEAMing technology and its future possibilities as an advanced cancer diagnostic will be briefly summarized. [Review].

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助