[Vancomycin-Resistant Enterococci]。

Shunji Takakura
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引用次数: 0

摘要

自1996年以来,在日本各地发现了耐万古霉素肠球菌(VRE)。然而,发病率一直相对较低。2006年,我们组织了京都VRE监测小组,制定了VRE控制规划,并开展了调查,以控制京都疫区爆发后VRE的流行情况。研究时间为2005年至2010年。对粪便样本进行VRE筛选,采用聚合酶链反应(PCR)检测万古霉素耐药基因。VRE控制规划包括以实验室为基础的粪便VRE筛查系统、对住院患者的年度监测和促进适当的感染控制措施。在以实验室为基础的常规粪便VRE筛查的医院中,VRE检出的患者数量明显较少。从年度监测来看,参加年度监测的患者中粪便VRE携带率上升至2007年,在2,035名入组患者中达到24例(1.2%)。这一比例从2008年开始下降,到2010年,在2408名入组患者中,这一比例降至4人(0.17%)的低点。虽然VRE确实在京都地区传播,但我们的项目成功地控制了VRE的总体传播。(审查)。
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[Vancomycin-Resistant Enterococci].

Vancomycin-resistant enterococci (VRE) have been detected from all over Japan since 1996. However, the incidence has been relatively low. In 2006, we organized Kyoto VRE surveillance group, established a VRE control program, and conducted an investigation which was to control the post-outbreak prevalence of VRE in the affected Kyoto region. The study period was from 2005 to 2010. Faecal samples were subjected to VRE screening, and vancomycin resistance genes were detected by polymerase chain reaction (PCR). A VRE control program consists of a laboratory-based faecal VRE screening system, annual surveillance of hospital inpatients and the promotion of adequate infection control measures. Number of VRE-detected patients was significantly smaller in hospitals with routine laboratory-based faecal VRE screening. From an- nual surveillance, the rate of faecal VRE carriage among the patients enrolled in the annual surveillance in- creased until 2007, when it reached 24(1.2%) of the 2,035 enrolled patients. The rate began to decrease in 2008 and, by 2010, reached a low of 4(0.17%) of the 2,408 enrolled patients. While VRE did spread within the Kyoto region, our program succeeded in controlling the overall VRE spread. [Review].

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