[一项回顾性研究原发性局灶性多汗症患者接受电视胸腔镜交感神经切除术后的生活质量]。

Joana Teixeira, Rosária Moreira, Manuela Vieira, José António Miranda, João Carlos Mota
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引用次数: 0

摘要

背景:原发性局灶性多汗症影响总人口的1%至4%,青少年和年轻人的患病率较高。该病的特点是一个或多个身体部位出汗过多,最常见的是手掌、面部、腋窝和脚底。这种情况会对患者的生活质量产生重大的负面影响。局灶性多汗症的病理生理被认为是由于过度的交感刺激,胸腔镜交感神经切除术是公认的治疗形式。本研究的目的是评估胸腔镜交感神经切除术患者术后的生活质量。材料和方法:本研究回顾性分析了2011年1月至2014年12月期间,在Casa de Saúde da Boavista心胸外科中心接受双侧胸腔镜胸交感神经切除术的54例原发性局灶性多汗症患者。采用生活质量问卷和多汗症严重程度量表对患者术前和术后3个月的生活质量进行评估。此外,还通过电话收集了关于中期后续行动的数据。所有患者均行全身麻醉,并行双侧胸腔镜交感神经链切除术。结果:女性占多数,占59.3%(32例)。平均年龄30.8±7.70岁(16 ~ 49岁)。手术前,85%的患者有严重的多汗症。79.6%的受访者表示,一般不适是由病情引起的,而功能-社会领域是他们生活中受影响最大的方面(61.1%)。围手术期并发症及术后主要并发症发生率为零,次要并发症发生率为5.5%。治疗3个月后,患者生活质量改善率为100%,满意度为96.3%,代偿性多汗症发生率为53.7%。57.3%的患者报告功能-社会领域有显著改善。中期随访(平均6年)对31例患者(占总人数的57.4%)进行了评估,其中77.4%的患者维持代偿性多汗症。93.5%的人对手术结果非常满意,并声称他们的生活质量提高了93.5%。中期随访评价为94%,中期随访评价为94.4%,3个月后评价为94.4%。结论:胸腔镜下交感神经切除术是治疗原发性局灶性多汗症的有效方法。尽管有时会观察到代偿性多汗症,但该手术产生了非常令人满意的结果,特别是在患者术后生活质量方面。
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[A retrospective study on the quality of life of patients with primary focal hyperhidrosis that underwent a video-assisted thoracoscopic sympathectomy].

Backgroud: Primary focal hyperhidrosis affects between 1 to 4% of the general population, with a higher prevalence in teenagers and young adults. The condition is characterized by excessive sweating in 1 or more body part, most often the palms, face, armpits and soles. This condition causes a significant negative impact on patient's quality of life. The pathophysiology of focal hyperhidrosis is believed to be due to excessive sympathetic stimulation, and videothoracoscopic sympathectomy is a recognized form of treatment. The aim of this study is to evaluate the post-operative quality of life of patients who underwent thoracoscopic sympathectomy.

Materials and methods: This is a retrospective study of fifty-four patients with primary focal hyperhidrosis submitted to bilateral thoracoscopic thoracic sympathectomy at the Center of Cardiothoracic Surgery of Casa de Saúde da Boavista, between January 2011 and December 2014. The Quality of Life questionnaire and the Hyperhidrosis Severity Scale questionnaire were used to evaluate the quality of life in the pre-operative period and 3 months after surgery. Further to this, data was collected regarding medium-term follow-up by telephone. All patients underwent general anesthesia and had bilateral video-assisted thoracoscopic resection of the sympathetic chain.

Results: The majority of patients are females 59.3% (32). The mean age is 30.8 ± 7.70 (between 16 and 49 years). Prior to surgery, 85% of the patients had severe hyperhidrosis. 79.6% of respondents stated that general discomfort was promoted by the condition, with the Funcional-Social domain being the most affected aspect of their life (61.1%). The rates of peri-operative complications and major post-operative complications were null, and minor complications were 5.5%. After 3 months, improvement in patient's quality of life and satisfaction level were of 100% and 96.3% respectively, however compensatory hyperhidrosis was observed in 53.7% of patients. 57.3% of the patients reported significant improvements in the Funcional-Social domain. Medium-term follow-up (mean=6 years) allowed for the evaluation of 31 patients (57.4% of the population), of whom 77.4% maintained compensatory hyperhidrosis. 93.5% reported to be highly satisfied with the surgical results and claimed to have improved their quality of life by 93.5%. 94% and 94.4% respectively of the patients evaluated in the medium term follow-up and after 3 months and in the medium term follow-up, recommend the surgery.

Conclusion: Sympathectomy by video-assisted thoracoscopic surgery (VATS) is an effective and viable therapeutic option for primary focal hyperhidrosis patients. Despite compensatory hyperhidrosis being observed at time, this procedure produces very satisfactory results particularly in regard to the patient's post-operative quality of life.

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