通过添加生物玻璃来控制硫酸钙的降解行为。

IF 4.4 3区 医学 Q2 ENGINEERING, BIOMEDICAL Progress in Biomaterials Pub Date : 2019-06-01 Epub Date: 2019-05-24 DOI:10.1007/s40204-019-0116-7
Pei-Yi Hsu, Hsiao-Chun Kuo, Wei-Hsing Tuan, Shao-Ju Shih, Makio Naito, Po-Liang Lai
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引用次数: 12

摘要

采用烧结法制备生物活性硫酸钙/玻璃复合材料,采用喷雾热解法制备Ca-P-Si玻璃颗粒。这种玻璃在模拟体液中形成磷灰石的能力方面表现出生物活性。在加热阶段,玻璃分别转变为磷酸钙和硅酸钙两种结晶相。结晶相的存在延缓了硫酸钙的致密化。制备复合材料需要1200℃的高温烧结。玻璃添加量的增加提高了硫酸钙的强度,降低了硫酸钙的降解率。这种新型复合材料不仅可降解,而且具有生物活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Manipulation of the degradation behavior of calcium sulfate by the addition of bioglass.

A bioactive calcium sulfate/glass composite was prepared using a sintering technique, and Ca-P-Si glass particles were prepared by spray pyrolysis. The glass exhibited bioactivity in terms of its ability to form apatite in a simulated body fluid. The glass was transformed into two crystallized phases, i.e., calcium phosphate and calcium silicate, respectively, during the heating stage. The presence of the crystallized phases retarded the densification of calcium sulfate. A high sintering temperature of 1200 °C was needed to prepare the composite. The increased addition of glass enhanced the strength and decreases the degradation rate of calcium sulfate. The new composite is not only degradable but also bioactive.

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来源期刊
Progress in Biomaterials
Progress in Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
9.60
自引率
4.10%
发文量
35
期刊介绍: Progress in Biomaterials is a multidisciplinary, English-language publication of original contributions and reviews concerning studies of the preparation, performance and evaluation of biomaterials; the chemical, physical, biological and mechanical behavior of materials both in vitro and in vivo in areas such as tissue engineering and regenerative medicine, drug delivery and implants where biomaterials play a significant role. Including all areas of: design; preparation; performance and evaluation of nano- and biomaterials in tissue engineering; drug delivery systems; regenerative medicine; implantable medical devices; interaction of cells/stem cells on biomaterials and related applications.
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