Buyisile Chibi, Neusa F Torres, Zinhle P Sokhela, Tivani P Mashamba-Thompson
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引用次数: 4
摘要
背景:除了不断影响HIV感染者(PLWH)的多种感染和频繁疼痛外，各种危险因素可能导致处方药转移。该研究的目的是绘制现有证据的危险因素，有助于处方药转移在PLWH。方法:Arksey和O'Malley的框架和Levac et al.(2010)的建议指导了本研究。我们从以下数据库检索相关文献:PubMed;谷歌学者;EBSCOhost(学术检索完整，MEDLINE和报纸来源)，Cochrane, WHO, HIV, ScienceDirect和开放获取论文。纳入了1996年1月至2017年7月期间发表的报告导致处方药转移风险因素证据的研究。进行主题内容分析，总结研究结果。结果:搜索确定了734项研究。在对符合条件的研究进行全文筛选后，在纳入的20项研究中报告了导致PLWH处方药转移的危险因素。研究发现，中低收入国家公共卫生服务人员处方药转移的研究有限。导致处方药转移的风险因素是药物使用者或药物依赖者;男性;年轻的;年轻的;被指责;未披露艾滋病毒状况;被诊断有精神健康问题;感染艾滋病毒;健康状况不佳;白色;无家可归的:无家可归或没有家的;受教育程度低的;有挪用、误用、滥用历史的;持有成瘾性处方的;失业，邻里关系高度混乱。结论:有证据表明，对中低收入国家PLWH中处方药转移的研究有限。研究结果表明，导致处方药转移的危险因素与HIV传播和感染的危险因素有关。普洛斯彼罗注册号:CRD42017074076。
Risk factors for prescription drug diversion among people living with HIV: a systematic scoping review.
Background: In addition to numerous infections and frequent pain constantly affecting people living with HIV (PLWH), various risk factors might contribute to prescription drug diversion. The purpose of the study is to map existing evidence on risk factors contributing to prescription drug diversion among PLWH.
Methods: Arksey and O'Malley's framework and the recommendation by Levac et al. (2010) guided this study. We searched for relevant literature from the following databases: PubMed; Google Scholar; EBSCOhost (Academic Search Complete, MEDLINE and Newspaper Source), Cochrane, WHO, HIV, ScienceDirect and Open Access Theses and Dissertations. Studies reporting evidence on risk factors contributing to prescription drug diversion and published in the period January 1996 to July 2017 were included. Thematic content analysis was performed to summarize the findings.
Results: The search identified 734 studies. After full-text screening of the eligible studies, risk factors contributing to prescription drug diversion among PLWH were reported in 20 included studies. It was found that there is limited research on prescription drug diversion among PLWH in low-middle-income countries (LMICs). Risk factors contributing to prescription drug diversion were being a substance user or substance dependent; being male; young in age; being stigmatized; not disclosed HIV status; diagnosed with mental health problems; being HIV infected; poor health and well being; being White; being homeless or not owing a home; having low educational level; having history of diversion, misuse or abuse; in possession of addictive prescriptions; being unemployed and living in high neighbourhood disorder.
Conclusion: Evidence shows that there is limited research on prescription drug diversion among PLWH in LMICs. The study findings show that the risk factors contributing to prescription drug diversion are related with risk factors for HIV transmission and infection.
期刊介绍：
The International Journal of Evidence-Based Healthcare is the official journal of the Joanna Briggs Institute. It is a fully refereed journal that publishes manuscripts relating to evidence-based medicine and evidence-based practice. It publishes papers containing reliable evidence to assist health professionals in their evaluation and decision-making, and to inform health professionals, students and researchers of outcomes, debates and developments in evidence-based medicine and healthcare.
The journal provides a unique home for publication of systematic reviews (quantitative, qualitative, mixed methods, economic, scoping and prevalence) and implementation projects including the synthesis, transfer and utilisation of evidence in clinical practice. Original scholarly work relating to the synthesis (translation science), transfer (distribution) and utilization (implementation science and evaluation) of evidence to inform multidisciplinary healthcare practice is considered for publication. The journal also publishes original scholarly commentary pieces relating to the generation and synthesis of evidence for practice and quality improvement, the use and evaluation of evidence in practice, and the process of conducting systematic reviews (methodology) which covers quantitative, qualitative, mixed methods, economic, scoping and prevalence methods. In addition, the journal’s content includes implementation projects including the transfer and utilisation of evidence in clinical practice as well as providing a forum for the debate of issues surrounding evidence-based healthcare.
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