与HIV和HCV感染相关的风险和保护因素在有性行为的高中男生中的流行-夏威夷,2013、2015和2017

Joshua R Holmes, Heather B Clayton, Thaddeus Pham, Alice K Asher, Ranjani R Starr
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摘要

人类免疫缺陷病毒(HIV)和丙型肝炎病毒(HCV)感染在年轻人中呈上升趋势,而男男性行为者(MSM)感染这两种病毒的风险很高。夏威夷有限的数据表明,在多大程度上,男同性恋者等人群的行为会增加他们感染这两种疾病的风险。该分析量化了夏威夷公立高中男同性恋者和有感染丙型肝炎病毒和艾滋病毒风险的学生的比例。结合2013年、2015年和2017年夏威夷青少年风险行为调查(YRBS)的数据(n=16,751),调查MSM公立高中学生中与HIV和HCV感染相关的风险因素(如性风险行为、物质使用)和保护因素的流行情况。在有过性经历的男学生(n= 3391)中,13.1%被归类为男男性行为者,其中40.3%的人尽管报告过同性性接触,但仍被认定为异性恋者。多变量模型表明,男同性恋者比非男同性恋者更有可能从事增加其感染艾滋病毒和丙型肝炎病毒风险的行为(复合风险变量;校正患病率:1.40,95% CI 1.15 - 1.70),且存在保护因素的可能性显著降低。以证据为基础的预防策略,在夏威夷性少数群体青年中减少HIV和HCV风险行为,同时改善保护因素,是必要的,必须解决性行为以及性取向的其他方面。
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Prevalence of Risk and Protective Factors Associated with HIV and HCV Infections Among Male High School Students Who Have Sex with Males-Hawai'i, 2013, 2015, and 2017.

Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections are increasing among young adults, and males who have sex with males (MSM) are at high risk for both infections. Limited Hawai'i data exists on the extent to which populations, such as MSM, are engaging in behaviors that place them at increased risk for either infection. This analysis quantified the proportion of Hawai'i public high school students who are MSM and are at risk for HCV and HIV infections. Data from the 2013, 2015, and 2017 Hawai'i Youth Risk Behavior Surveys (YRBS) were combined (n=16,751) to investigate the prevalence of risk factors associated with HIV and HCV infections (eg, sexual risk behaviors, substance use) and protective factors among MSM public high school students. Among sexually experienced male students (n=3,391), 13.1% were classified as MSM and among these, 40.3% identified as heterosexual despite reporting same-sex sexual contact. Multivariate modeling demonstrated that MSM students are significantly more likely than non-MSM students to engage in behaviors that increase their risk for HIV and HCV infections (composite risk variable; adjusted Prevalence Ratio: 1.40, 95% CI 1.15 - 1.70) and are significantly less likely to have protective factors. Evidence-based prevention strategies for reducing HIV and HCV risk behaviors while improving protective factors among sexual minority youth in Hawai'i are necessary and must address sexual behavior along with other dimensions of sexual orientation.

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