足部支足麦氏菌感染:非流行地区一种被忽视的热带病病例报告。

Q2 Medicine BMC Dermatology Pub Date : 2020-01-10 DOI:10.1186/s12895-019-0097-1
Basma Karrakchou, Ibtissam Boubnane, Karima Senouci, Badreddine Hassam
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引用次数: 12

摘要

背景:足菌肿是一种罕见的皮肤和皮下组织慢性肉芽肿感染,可由丝状细菌(放线菌瘤)或真菌(真菌瘤)引起。它是第三和第四个十年之间的年轻人的特权,并通过造成接种点的任何创伤传播。典型的临床三联征包括无痛、坚硬和肿胀的皮下肿块、多个瘘管和典型的颗粒排出。尽管足菌肿在许多热带和亚热带国家流行,但也可在摩洛哥等非流行地区发现,并造成诊断问题,导致长期并发症。因此,我们应该提高对这种被忽视疾病的认识,以便及早治疗。然而,在医学治疗下,足菌肿愈合缓慢,经常需要手术,并且有可能复发。病例介绍:在此,我们报告一例64岁的患者,有十年前发生的脓肿史,口服特比萘芬联合手术治疗。2年后完全缓解。他六个月前的伤疤又复发了。磁共振成像(MRI)未见骨受累。患者口服特比萘芬,结果缓慢但积极。结论:通过本病例报告,我们进行了文献回顾,并强调在临床实践中提高对足菌肿的认识的重要性,特别是在非流行地区。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region.

Background: Mycetoma is an uncommon chronic granulomatous infection of cutaneous and subcutaneous tissues that can be caused by filamentous bacteria (actinomycetoma) or fungi (eumycetoma). It is the prerogative of young men between the third and fourth decade and is transmitted through any trauma causing an inoculating point. The classic clinical triad associates a painless hard and swelling subcutaneous mass, multiple fistulas, and the pathognomonic discharge of grains. Although endemic in many tropical and subtropical countries, mycetoma can also be found in non-endemic areas as in Morocco, and causes then diagnosis problems leading to long lasting complications. Therefore, we should raise awareness of this neglected disease for an earlier management. Under medical treatment however, mycetoma has a slow healing and surgery is often needed, and relapses are possible.

Case presentation: Herein we report a case of a 64 years old patient, with a history of eumycetoma occurring ten years ago treated with oral terbinafine coupled with surgery. A complete remission was seen after 2 years. He presented a relapse on the previous scar 6 months ago. There wasn't any bone involvement in the magnetic resonance imaging (MRI). The patient was put under oral terbinafine with a slow but positive outcome.

Conclusion: Through this case report, we perform a literature review and highlight the importance of increase awareness of mycetoma in clinical practice especially in non-endemic regions.

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来源期刊
BMC Dermatology
BMC Dermatology Medicine-Dermatology
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期刊介绍: BMC Dermatology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of skin disorders, as well as related molecular genetics, pathophysiology, and epidemiology. BMC Dermatology (ISSN 1471-5945) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus and Google Scholar.
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