槲皮素对实验性牙周炎发展过程中抗氧化潜能的影响

Andrii Demkovych, Yurii Bondarenko, Petro Hasiuk
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摘要

本文介绍了抗氧化系统的实验研究结果。在实验性牙周炎发生的第 7 天和第 14 天,对超氧化物歧化酶活性、过氧化氢酶和脑磷脂进行了测定。因此,在炎症过程的急性期,超氧化物歧化酶活性降低,过氧化氢酶活性增强,血清中的脑磷脂保持不变。使用黄酮类化合物 7 天后,实验性细菌免疫性牙周炎大鼠血浆中的超氧化物歧化酶活性降低,过氧化氢酶活性和脑磷脂浓度维持在较高水平,从而使自由基氧化作用趋于稳定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Effects of quercetin on antioxidant potential in the experimental periodontitis development.

The results of experimental research of antioxidant system are presented in this article. Superoxide dismutase activity, catalase, and ceruloplasmin have been determined on the 7th and 14th days of experimental periodontitis development both without correction and with the injection of a water-soluble quercetin drug (corvitin). Hence, there was a decrease in superoxide dismutase activity, intensive increase in catalase activity, and ceruloplasmin maintenance in the blood serum during acute period of inflammatory process. The usage of flavonoid for 7  days resulted in stabilization of radical oxidation due to reduction of superoxide dismutase activity, maintenance at the high-level catalase activity, and ceruloplasmin concentration in the rat's blood plasma with experimental bacterial-immune periodontitis.

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来源期刊
Interventional Medicine and Applied Science
Interventional Medicine and Applied Science MEDICINE, GENERAL & INTERNAL-
CiteScore
1.60
自引率
0.00%
发文量
0
审稿时长
15 weeks
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