撒哈拉以南非洲儿童和青少年超重/肥胖及相关心血管危险因素:范围审查

Simeon-Pierre Choukem, Joel Noutakdie Tochie, Aurelie T Sibetcheu, Jobert Richie Nansseu, Julian P Hamilton-Shield
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摘要

最近,儿童和青少年超重/肥胖在发展中国家不成比例地增加,据估计,儿童和青少年未来可确定的心血管疾病负担也将平行增加。确定与儿童和青少年超重/肥胖相关的心血管危险因素(CVRF)对于制定心血管疾病预防干预措施至关重要。虽然这在高收入国家进行了广泛的研究,但在撒哈拉以南非洲(SSA)缺乏一致或具有代表性的数据。目的:本综述综合了SSA儿童和青少年中CVRF与超重和肥胖相关的当代研究,为该人群中超重/肥胖和心血管疾病的当前负担提供证据。方法:我们检索MEDLINE和谷歌Scholar截至2019年7月31日的观察性、实验性研究和系统综述,涉及无语言限制的SSA儿童和青少年超重/肥胖和CVRF。四名调查人员分成四对,独立地选择和提取相关数据。评估了所有纳入研究的方法学质量。结果:我们纳入了88项研究,共涉及来自20个SSA国家的86,637名儿童和青少年。偏倚风险低的有62项(70.5%),中等偏倚的有18项(20.5%),高偏倚的有8项(9%)。SSA儿童和青少年的超重/肥胖正以惊人的速度增长。其主要关联包括缺乏身体活动、不健康饮食、高社会经济地位、性别和高产妇体重指数。超重/肥胖SSA儿童和青少年CVRF主要为代谢综合征、高血压、血脂异常、糖尿病和葡萄糖耐受不良。对于超重/肥胖SSA儿童和青少年的儿童超重/肥胖或CVRF的管理缺乏指南或共识。结论:目前的研究结果表明,迫切需要审查SSA国家当前的卫生政策。需要进行健康教育,并将目前SSA儿童和青少年的肥胖环境转变为促进体育活动和健康饮食习惯的环境。
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Overweight/obesity and associated cardiovascular risk factors in sub-Saharan African children and adolescents: a scoping review.

Introduction: Recently, childhood and adolescence overweight/obesity has increased disproportionately in developing countries, with estimates predicting a parallel increase in future cardiovascular disease (CVD) burden identifiable in childhood and adolescence. Identifying cardiovascular risk factors (CVRF) associated with childhood and adolescence overweight/obesity is pivotal in tailoring preventive interventions for CVD. Whilst this has been examined extensively in high-income countries, there is scant consistent or representative data from sub-Saharan Africa (SSA).

Objective: This scoping review synthesises contemporary studies on CVRF associated with overweight and obesity in SSA children and adolescents to provide evidence on the current burden of overweight/obesity and CVD in this population.

Methods: We searched MEDLINE and Google Scholar up to July 31, 2019 for observational and experimental studies and systematic reviews addressing childhood and adolescence overweight/obesity and CVRF in SSA without language restriction. Four investigators working in four pairs, independently selected and extracted the relevant data. The methodological quality of all included studies was assessed.

Results: We included 88 studies with a total of 86,637children and adolescents from 20 SSA countries. The risk of bias was low in 62 (70.5%), moderate 18 (20.5%), and high in eight (9%) studies. Overweight/obesity in SSA children and adolescents is rising at an alarming rate. Its main associations include physical inactivity, unhealthy diets, high socio-economic status, gender and high maternal body mass index. Identified CVRF in overweight/obese SSA children and adolescents are mainly metabolic syndrome, hypertension, dyslipidaemia, diabetes and glucose intolerance. There is a dearth of guidelines or consensus on the management of either childhood overweight/obesity or CVRF in overweight/obese SSA children and adolescents.

Conclusion: The current findings suggest an urgent need to review current health policies in SSA countries. Health education and transforming the current obesogenic environment of the SSA child and adolescent into one which promotes physical activity and healthy dietary habits is required.

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