一系列光照条件下昼夜节律夹带的表型可塑性

Q2 Medicine Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-11-01 DOI:10.1016/j.nbscr.2020.100055

C.R.C. Moreno , K. Wright Jr. , D.J. Skene , F.M. Louzada

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引用次数: 8

摘要

对授时基因的反应，特别是光/暗周期，可能在表型上有所不同。表型可塑性可以定义为一个基因组在响应环境变化时表达不同表型的能力。在这篇观点论文中，我们提出了一些证据，证明将电灯引入人类日常生活的最显著影响之一是显着增加了表型可塑性和个体间携带阶段的差异。我们认为，表型可塑性的健康极限在当代社会已经被超越。

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Phenotypic plasticity of circadian entrainment under a range of light conditions

The response to a zeitgeber, particularly the light/dark cycle, may vary phenotypically. Phenotypic plasticity can be defined as the ability of one genome to express different phenotypes in response to environmental variation. In this opinion paper, we present some evidence that one of the most prominent effects of the introduction of electric light to the everyday life of humans is a significant increase in phenotypic plasticity and differences in interindividual phases of entrainment. We propose that the healthy limits of phenotypic plasticity have been surpassed in contemporary society.

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来源期刊

Neurobiology of Sleep and Circadian Rhythms Neuroscience-Behavioral Neuroscience

CiteScore

4.50

自引率

0.00%

发文量

审稿时长

69 days

期刊介绍： Neurobiology of Sleep and Circadian Rhythms is a multidisciplinary journal for the publication of original research and review articles on basic and translational research into sleep and circadian rhythms. The journal focuses on topics covering the mechanisms of sleep/wake and circadian regulation from molecular to systems level, and on the functional consequences of sleep and circadian disruption. A key aim of the journal is the translation of basic research findings to understand and treat sleep and circadian disorders. Topics include, but are not limited to: Basic and translational research, Molecular mechanisms, Genetics and epigenetics, Inflammation and immunology, Memory and learning, Neurological and neurodegenerative diseases, Neuropsychopharmacology and neuroendocrinology, Behavioral sleep and circadian disorders, Shiftwork, Social jetlag.