囊性纤维化成人的游戏机家庭运动:研究方案。

John D Lowman, George M Solomon, Steven M Rowe, Hon K Yuen
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引用次数: 0

摘要

背景:尽管有证据表明运动对肺功能有益,但囊性纤维化(CF)成人患者坚持常规运动的程度很低。将交互式虚拟现实视频游戏活动结合到家庭项目中,作为一种激励,可能有助于提高锻炼的积极性和坚持性。本研究将尝试通过任天堂Wii Fit Plus™家庭运动项目来改善久坐的CF患者的身体健康和呼吸功能。方法:采用单组前测后测设计,对久坐不动的CF患者进行家庭运动项目,对改善肺相关功能(身体健康和呼吸功能)的即时(12周)和长期(24周)效果进行检验。参与者将获得Wii Fit Plus的一次性指导,并要求在接下来的24周内按照推荐的指导方针每周锻炼3次,每次30分钟。在前12周将进行每月电话监测。除了评估基于家庭的exergame项目在改善有氧能力、身体活动和呼吸相关症状方面的功效外,我们还将研究exergame对通过鼻电位差测量的气道离子运输的影响,该影响将仅在基线和12周结束时收集。讨论:本研究首次评估了一种低成本运动途径(即exergames)对成年CF患者改善肺相关功能的可行性、可接受性和潜在有效性,这对CF疾病管理和并发症预防具有重要意义。此外,这项拟议的研究将首次调查家庭运动对CF成人气道离子运输的治疗效果。通过增加身体活动,预计参与者在研究结束时将改善他们的身体健康和呼吸功能。试验注册:ClinicalTrials.gov ID: NCT02277860。
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Gaming Console Home-Based Exercise for Adults with Cystic Fibrosis: Study Protocol.

Background: Despite evidence of exercise benefits to lung function, adherence to routine exercise in adults with cystic fibrosis (CF) is low. The incorporation of interactive virtual reality video exergame activities in home-based programs as an incentive may help improve motivation and adherence to exercise. This proposed study will attempt to improve the physical fitness and respiratory function of sedentary adults with CF by engaging them in a Nintendo Wii Fit Plus™ home-based exercise program.

Methods: A single group pretest-posttest design will be used to examine the immediate (12-weeks) and long-term effect (24-weeks) of a home-based exergame program on improving pulmonary-related function (physical fitness and respiratory function) in sedentary adults with CF. Participants will receive a one-time orientation to the Wii Fit Plus, and will be requested to use it to exercise according to the recommended guidelines 3 times a week for 30 min in the following 24 weeks. Monthly phone monitoring will be conducted during the first 12 weeks. Besides evaluating the efficacy of a home-based exergame program on improving aerobic capacity, physical activity, and respiratory-related symptoms, we will examine the impact of the exergame on airway ion transport as measured by nasal potential difference, which will be collected at baseline and at the end of 12-weeks only.

Discussion: This is the first study to evaluate the feasibility, acceptability and potential effectiveness of a low-cost exercise avenue (i.e., exergames) for adults with CF to improve their pulmonary-related function, which is important for CF disease management and prevention of complications. In addition, the proposed study will be the first to investigate the therapeutic efficacy of home-based exergames on airway ion transport among adults with CF. Through an increase in physical activity, it is expected that participants will improve their physical fitness and respiratory function at the end of the study.

Trial registration: ClinicalTrials.gov ID: NCT02277860.

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