{"title":"路易体痴呆和阿尔茨海默病的蔬菜新鲜度感知。","authors":"Yuka Oishi, Toru Imamura, Tatsuo Shimomura, Kyoko Suzuki","doi":"10.1159/000508282","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Although various visual function deficits have been reported in patients with Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), vegetable freshness perception has not been thoroughly examined.</p><p><strong>Objective: </strong>To investigate vegetable freshness perception in patients with AD and DLB and to clarify the relationship between vegetable freshness perception and various visuoperceptual functions.</p><p><strong>Methods: </strong>We enrolled 37 patients with probable DLB, 58 patients with probable AD, and 32 age-matched healthy controls. We assessed vegetable freshness perception and visuoperceptual functions, including vegetable brightness perception, contrast sensitivity, color perception, and stereopsis. Patients with DLB showed disproportionate deficits in vegetable freshness perception and vegetable luminance perception compared to patients with AD and controls. Analyses of the groups with higher and lower vegetable freshness perceptions revealed significant differences in contrast sensitivity and visual texture recognition.</p><p><strong>Results: </strong>In the vegetable freshness test, we found significant differences among the 3 groups (<i>F</i> = 30.029, <i>p</i> < 0.0001); the extent of impairment in patients with DLB was greater than that in patients with AD. In patients with DLB, the vegetable freshness judgments were significantly correlated with texture judgment scores and contrast sensitivity.</p><p><strong>Conclusion: </strong>Our findings revealed significantly impaired vegetable freshness perception in patients with DLB. Vegetable freshness perception may be related to visual texture recognition in patients with DLB.</p>","PeriodicalId":38017,"journal":{"name":"Dementia and Geriatric Cognitive Disorders Extra","volume":"10 2","pages":"74-85"},"PeriodicalIF":1.4000,"publicationDate":"2020-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000508282","citationCount":"0","resultStr":"{\"title\":\"Vegetable Freshness Perception in Dementia with Lewy Bodies and Alzheimer's Disease.\",\"authors\":\"Yuka Oishi, Toru Imamura, Tatsuo Shimomura, Kyoko Suzuki\",\"doi\":\"10.1159/000508282\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Although various visual function deficits have been reported in patients with Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), vegetable freshness perception has not been thoroughly examined.</p><p><strong>Objective: </strong>To investigate vegetable freshness perception in patients with AD and DLB and to clarify the relationship between vegetable freshness perception and various visuoperceptual functions.</p><p><strong>Methods: </strong>We enrolled 37 patients with probable DLB, 58 patients with probable AD, and 32 age-matched healthy controls. We assessed vegetable freshness perception and visuoperceptual functions, including vegetable brightness perception, contrast sensitivity, color perception, and stereopsis. Patients with DLB showed disproportionate deficits in vegetable freshness perception and vegetable luminance perception compared to patients with AD and controls. Analyses of the groups with higher and lower vegetable freshness perceptions revealed significant differences in contrast sensitivity and visual texture recognition.</p><p><strong>Results: </strong>In the vegetable freshness test, we found significant differences among the 3 groups (<i>F</i> = 30.029, <i>p</i> < 0.0001); the extent of impairment in patients with DLB was greater than that in patients with AD. In patients with DLB, the vegetable freshness judgments were significantly correlated with texture judgment scores and contrast sensitivity.</p><p><strong>Conclusion: </strong>Our findings revealed significantly impaired vegetable freshness perception in patients with DLB. 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引用次数: 0
摘要
导语:虽然阿尔茨海默病(AD)和路易体痴呆(DLB)患者有各种视觉功能缺陷的报道,但蔬菜新鲜度感知尚未得到彻底的检查。目的:探讨AD和DLB患者的蔬菜新鲜度知觉,阐明蔬菜新鲜度知觉与各种视知觉功能的关系。方法:我们招募了37名可能患有DLB的患者,58名可能患有AD的患者和32名年龄匹配的健康对照。我们评估了蔬菜新鲜度感知和视觉感知功能,包括蔬菜亮度感知、对比敏感度、颜色感知和立体视觉。与AD患者和对照组相比,DLB患者在蔬菜新鲜度和蔬菜亮度感知方面表现出不成比例的缺陷。对蔬菜新鲜度感知较高和较低的组的分析显示,对比敏感度和视觉纹理识别存在显著差异。结果:在蔬菜新鲜度测试中,3组间差异有统计学意义(F = 30.029, p < 0.0001);DLB患者的损伤程度大于AD患者。在DLB患者中,蔬菜新鲜度判断与质地判断评分和对比敏感度显著相关。结论:我们的研究结果显示,DLB患者对蔬菜新鲜度的感知明显受损。蔬菜新鲜度感知可能与DLB患者的视觉纹理识别有关。
Vegetable Freshness Perception in Dementia with Lewy Bodies and Alzheimer's Disease.
Introduction: Although various visual function deficits have been reported in patients with Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), vegetable freshness perception has not been thoroughly examined.
Objective: To investigate vegetable freshness perception in patients with AD and DLB and to clarify the relationship between vegetable freshness perception and various visuoperceptual functions.
Methods: We enrolled 37 patients with probable DLB, 58 patients with probable AD, and 32 age-matched healthy controls. We assessed vegetable freshness perception and visuoperceptual functions, including vegetable brightness perception, contrast sensitivity, color perception, and stereopsis. Patients with DLB showed disproportionate deficits in vegetable freshness perception and vegetable luminance perception compared to patients with AD and controls. Analyses of the groups with higher and lower vegetable freshness perceptions revealed significant differences in contrast sensitivity and visual texture recognition.
Results: In the vegetable freshness test, we found significant differences among the 3 groups (F = 30.029, p < 0.0001); the extent of impairment in patients with DLB was greater than that in patients with AD. In patients with DLB, the vegetable freshness judgments were significantly correlated with texture judgment scores and contrast sensitivity.
Conclusion: Our findings revealed significantly impaired vegetable freshness perception in patients with DLB. Vegetable freshness perception may be related to visual texture recognition in patients with DLB.
期刊介绍:
This open access and online-only journal publishes original articles covering the entire spectrum of cognitive dysfunction such as Alzheimer’s and Parkinson’s disease, Huntington’s chorea and other neurodegenerative diseases. The journal draws from diverse related research disciplines such as psychogeriatrics, neuropsychology, clinical neurology, morphology, physiology, genetic molecular biology, pathology, biochemistry, immunology, pharmacology and pharmaceutics. Strong emphasis is placed on the publication of research findings from animal studies which are complemented by clinical and therapeutic experience to give an overall appreciation of the field. Dementia and Geriatric Cognitive Disorders Extra provides additional contents based on reviewed and accepted submissions to the main journal Dementia and Geriatric Cognitive Disorders Extra .