灵长类动物多样性:从生物医学到保护基因组学。

IF 8.7 1区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Annual Review of Animal Biosciences Pub Date : 2021-02-16 Epub Date: 2020-11-16 DOI:10.1146/annurev-animal-061220-023138
Joseph D Orkin, Lukas F K Kuderna, Tomas Marques-Bonet
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引用次数: 8

摘要

到目前为止,灵长类基因组学领域主要集中在两个主题上:理解人类进化和推进生物医学研究。我们建议现在应该关注第三个主题:保护基因组学。由于人类活动的影响,大多数灵长类物种面临灭绝的威胁。一个更强大的灵长类动物保护基因组学将允许基因知情的种群管理。由于测序成本的稳步下降,现在在种群水平上对整个灵长类基因组进行测序已经成为可能。此外,非侵入性基因组方法的技术进步使得从非侵入性生物材料中获取基因组规模数据成为可能。在这里,我们回顾了灵长类动物多样性分析的最新进展,重点是跨辐射的基因组数据集。
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The Diversity of Primates: From Biomedicine to Conservation Genomics.

Until now, the field of primate genomics has focused on two major themes: understanding human evolution and advancing biomedical research. We propose that it is now time for a third theme to receive attention: conservation genomics. As a result of anthropogenic effects, the majority of primate species have become threatened with extinction. A more robust primate conservation genomics will allow for genetically informed population management. Thanks to a steady decline in the cost of sequencing, it has now become feasible to sequence whole primate genomes at the population level. Furthermore, technological advances in noninvasive genomic methods have made it possible to acquire genome-scale data from noninvasive biomaterials. Here, we review recent advances in the analysis of primate diversity, with a focus on genomic data sets across the radiation.

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来源期刊
Annual Review of Animal Biosciences
Annual Review of Animal Biosciences BIOTECHNOLOGY & APPLIED MICROBIOLOGY-ZOOLOGY
CiteScore
21.30
自引率
0.80%
发文量
31
期刊介绍: The Annual Review of Animal Biosciences is primarily dedicated to the fields of biotechnology, genetics, genomics, and breeding, with a special focus on veterinary medicine. This includes veterinary pathobiology, infectious diseases and vaccine development, and conservation and zoo biology. The publication aims to address the needs of scientists studying both wild and domesticated animal species, veterinarians, conservation biologists, and geneticists.
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