埃塞俄比亚西北部阿姆哈拉地区西阿马奇霍区内脏利什曼病流行趋势。

IF 2.4 Q3 INFECTIOUS DISEASES Tropical Diseases, Travel Medicine and Vaccines Pub Date : 2020-11-27 DOI:10.1186/s40794-020-00125-z
Addisu Gize, Addisu Workineh, Taddesse Hailu
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引用次数: 2

摘要

背景:内脏利什曼病(VL)是一种由专性细胞内原生动物寄生虫引起的疾病,影响动物和人类。估计有320万人面临VL风险,埃塞俄比亚每年发生3700-7400例病例。以前报告的VL病例数量最多的是该国西北部地区,特别是西阿马基霍区。本研究的目的是确定VL在研究地区的流行趋势。方法:收集2010年1月至2015年8月在卫生中心进行血液检查的患者中VL的流行趋势。采用手指穿刺法采集血样,采用rK39抗体检测确诊感染。结果:9299例VL疑似病例中rK39抗体检测阳性1948例(21%)。其中原发黑热病1757例(90.2%),复发167例(8.6%),黑热病后皮肤利什曼病24例(1.2%)。结论:研究区VL患病率仍较高。因此,早期发现、诊断、治疗和及时分析至关重要。
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A trend prevalence of visceral Leishmaniasis in West Armachiho District, Amhara Region, Northwest Ethiopia.

Background: Visceral leishmaniasis (VL) is a disease caused by an obligate intracellular protozoan parasite that affects animals and humans. An estimated 3.2 million people are at risk of VL, and 3700-7400 cases occur annually in Ethiopia. The highest numbers of VL cases have been previously reported from the North Western parts of the country, especially in West Armachiho District. The aim of this study was to determine the trend prevalence of VL at the study area.

Methods: Health center based retrospective data were collected to determine the trend prevalence of VL among patients who had blood examination from January 2010 to August 2015. The blood samples were collected by finger pricking and the infections were confirmed by using rK39 antibody test.

Result: Of the 9299 VL suspected cases, 1948 (21%) were positive for rK39 antibody test. Of these, 1757 (90.2%) were primary kala-azar cases, 167 (8.6%) were relapse and the remaining 24 (1.2%) were post kala-azar dermal leishmaniasis cases.

Conclusions: The prevalence of VL is still high in the study area. Therefore, early case detection, diagnosis, treatment, and timely analysis are essential.

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来源期刊
CiteScore
5.20
自引率
0.00%
发文量
25
审稿时长
17 weeks
期刊介绍: Tropical Diseases, Travel Medicine and Vaccines is an open access journal that considers basic, translational and applied research, as well as reviews and commentary, related to the prevention and management of healthcare and diseases in international travelers. Given the changes in demographic trends of travelers globally, as well as the epidemiological transitions which many countries are experiencing, the journal considers non-infectious problems including chronic disease among target populations of interest as well as infectious diseases.
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