印度三级医疗中心药物处方统计的回顾性分析:促进谨慎用药的建议。

IF 0.8 Q4 PHARMACOLOGY & PHARMACY Journal of Research in Pharmacy Practice Pub Date : 2020-10-08 eCollection Date: 2020-07-01 DOI:10.4103/jrpp.JRPP_20_29
Ajaya Kumar Sahoo, Dhyuti Gupta, Suryaprakash Dhaneria, Pugazhenthan Thangaraju, Alok Singh
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引用次数: 4

摘要

目的:药物利用研究提供了有关医院环境中药物使用模式的信息,可用于促进药物的成本效益使用。本观察性回顾性研究旨在评估印度某三级医疗中心的药物使用模式,建立药物的基线消费数据,同时确定改进药物处方模式的目标。方法:本研究采用回顾性横断面研究方法,随机抽取印度全印医学科学研究所2019年8月各科室217份病历(采用系统随机抽样)进行评价。从医疗记录中提取有关基本人口统计细节、药物强度、途径和总量的信息,并最终估计出世界卫生组织(世卫组织)的核心指标。使用世卫组织解剖治疗化学/限定日剂量(ATC-DDD)方法评估药物利用数据。还分析了潜在的药物-药物相互作用。结果:以男性患者居多(56.2%)。用通用名开的药占50%。含有注射剂和抗菌剂的处方分别占68.1%和83.6%。49.3%的患者使用固定剂量联合用药,60.9%的患者使用的药物属于2015年国家基本药物目录。总共发现了15种潜在的药物相互作用。结论:大部分抗菌药及其他药物的计算处方日剂量接近WHO-DDD。商品名处方和多药是很常见的。抗生素占药品费用的大部分。
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Retrospective Analysis of Drug Prescription Statistics in a Tertiary Care Center in India: Recommendations for Promoting Prudent Utilization of Drugs.

Objective: Drug utilization studies provide information regarding the drug usage pattern in hospital settings, which can be used to promote cost-efficient uses of drugs. The present observational retrospective study was conducted to evaluate the drug utilization pattern in a tertiary care center in India and create a baseline consumption data for the drugs, simultaneously identifying targets for improving drug prescribing pattern.

Methods: The current retrospective cross-sectional study was conducted at All India Institute of Medical Sciences Raipur, wherein the 217 medical records of different departments for August 2019 were chosen randomly (using systematic random sampling) for evaluation. The information was extracted from medical records regarding the basic demographic details, drug strength, route, and total amount, and eventually, the World Health Organization (WHO) core indicators were estimated. Drug utilization data were assessed using the WHO Anatomical Therapeutic Chemical/Defined Daily Dose (ATC-DDD) methodology. Potential drug-drug interactions were also analyzed.

Findings: Most of the records analyzed were of male patients (56.2%). Drugs prescribed by their generic name were 50%. Prescriptions containing injection and antimicrobials were 68.1% and 83.6%, respectively. 49.3% of the patients had received a fixed-dose combination, and 60.9% of drugs belonged to the National List of Essential Medicines 2015. A total of 15 potential drug interactions were found.

Conclusion: Calculated prescribed daily dose of most of the antimicrobials and other groups of drugs was close to the WHO-DDD. Trade name prescription and polypharmacy were very common. Antibiotics accounted for the majority of drug costs.

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来源期刊
Journal of Research in Pharmacy Practice
Journal of Research in Pharmacy Practice PHARMACOLOGY & PHARMACY-
自引率
0.00%
发文量
8
审稿时长
21 weeks
期刊介绍: The main focus of the journal will be on evidence-based drug-related medical researches (with clinical pharmacists’ intervention or documentation), particularly in the Eastern Mediterranean region. However, a wide range of closely related issues will be also covered. These will include clinical studies in the field of pharmaceutical care, reporting adverse drug reactions and human medical toxicology, pharmaco-epidemiology and toxico-epidemiology (poisoning epidemiology), social aspects of pharmacy practice, pharmacy education and economic evaluations of treatment protocols (e.g. cost-effectiveness studies). Local reports of medication utilization studies at hospital or pharmacy levels will only be considered for peer-review process only if they have a new and useful message for the international pharmacy practice professionals and readers.
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