心外膜脂肪组织可预测勃起功能障碍患者的亚临床左心室功能障碍。

IF 2.7 4区医学 Q3 ENDOCRINOLOGY & METABOLISM Aging Male Pub Date : 2021-12-01 DOI:10.1080/13685538.2021.1945572

Hayati Eren, Muhammed Bahadır Omar, Ülker Kaya, Ertuğrul Gazi Özbey, Lütfi Öcal

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引用次数: 3

摘要

背景:勃起功能障碍(ED)是动脉粥样硬化和亚临床心肌功能障碍的早期形式。心外膜脂肪组织(EFT)与左心室(LV)功能受损相关，即使在没有心血管疾病的情况下。本研究的目的是通过斑点跟踪超声心动图(2D-STE)方法研究勃起性ED患者的EFT与左室收缩功能之间的关系。方法:将129例连续ED患者与145例年龄和性别匹配的对照组进行比较。使用国际勃起功能指数问卷对ED进行评估。用TTE法测定EFT厚度。采用2D-STE法测量左室纵向应变(LV- gls)和左室周向应变(LV- gcs)。结果:ED患者的EFT厚度显著高于ED患者(p vs.(-21.1±3.9,pv);结论:EFT厚度与ED患者亚临床左室收缩功能障碍相关。

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Epicardial fat tissue can predict subclinical left ventricular dysfunction in patients with erectile dysfunction.

Background: Erectile dysfunction (ED) is an early form of atherosclerosis and subclinical myocardial dysfunction. Epicardial fat tissue (EFT) is associated with impaired left ventricular (LV) function, even in the absence of cardiovascular disease. The aim of this study was to investigate the association between EFT and LV systolic function in patients with erectile ED by speckle tracking echocardiography (2D-STE) method.

Methods: A total of 129 consecutive patients with ED were compared with 145 age- and sex-matched control subjects. ED was evaluated using the International Index of Erectile Function questionnaire. Thickness of EFT was measured by TTE. Global LV longitudinal strain (LV-GLS) and global LV circumferential strain (LV-GCS) were measured by 2D-STE method.

Results: The EFT thickness was significantly higher in the patients with ED (p <.01). LV-GLS and LV-GCS were revealed to be more deterioration in the ED group compared to controls (-18.2 ± 2.7 vs. (-21.1 ± 3.9, p<.001; -19.5 ± 4.1 vs. -21.9 ± 3.9, p<.001, respectively). It has been shown that EFT thickness is an independent predictor of LV dysfunction.

Conclusions: These results indicate that EFT thickness is associated with subclinical LV systolic dysfunction in patients with ED.

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来源期刊

Aging Male 医学-泌尿学与肾脏学

CiteScore

6.40

自引率

3.80%

发文量

审稿时长

>12 weeks

期刊介绍： The Aging Male , the official journal of the International Society for the Study of the Aging Male, is a multidisciplinary publication covering all aspects of male health throughout the aging process. The Journal is a well-recognized and respected resource for anyone interested in keeping up to date with developments in this field. It is published quarterly in one volume per year. The Journal publishes original peer-reviewed research papers as well as review papers and other appropriate educational material that provide researchers with an integrated perspective on this new, emerging specialty. Areas of interest include, but are not limited to: Diagnosis and treatment of late-onset hypogonadism Metabolic syndrome and related conditions Treatment of erectile dysfunction and related disorders Prostate cancer and benign prostate hyperplasia.