计算机辅助脑肿瘤诊断:使用增强脑MRI的深度学习CNN的性能评估。

IF 3.3 Q2 ENGINEERING, BIOMEDICAL International Journal of Biomedical Imaging Pub Date : 2021-06-13 eCollection Date: 2021-01-01 DOI:10.1155/2021/5513500
Asma Naseer, Tahreem Yasir, Arifah Azhar, Tanzeela Shakeel, Kashif Zafar
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引用次数: 44

摘要

脑瘤是一种致命的神经系统疾病,由大脑或头骨内细胞的异常和不可控生长引起。这种疾病患者的死亡率正在逐渐上升。手动分析磁共振图像(MRI)不足以有效和准确地诊断脑肿瘤。疾病的早期诊断可以激活及时的治疗,从而提高患者的生存率。现代脑成像方法提高了脑肿瘤的检出率。在过去的几年里,人们对人脑肿瘤的计算机辅助诊断进行了大量的研究,以实现100%的诊断准确率。本研究的重点是通过卷积神经网络(CNN)对脑肿瘤进行早期诊断,以提高最先进的诊断准确性。所提出的CNN是在包含脑肿瘤MRI的基准数据集BR35H上训练的。模型的性能和可持续性在六个不同的数据集上进行评估,即BMI-i、BTI、BMI-II、BTS、BMI-III和BD-BT。为了提高模型的性能,并使其对完全看不见的数据具有可持续性,采用了不同的几何数据增强技术以及统计标准化。所提出的用于脑肿瘤诊断的基于CNN的CAD系统比其他系统表现更好,平均准确率约为98.8%,特异性约为0.99。它还揭示了两个大脑MRI数据集(即BTS和BD-BT)的100%正确诊断。将所提出的系统的性能与其他现有系统进行了比较,分析表明,所提出的体系优于所有现有体系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI.

Brain tumor is a deadly neurological disease caused by an abnormal and uncontrollable growth of cells inside the brain or skull. The mortality ratio of patients suffering from this disease is growing gradually. Analysing Magnetic Resonance Images (MRIs) manually is inadequate for efficient and accurate brain tumor diagnosis. An early diagnosis of the disease can activate a timely treatment consequently elevating the survival ratio of the patients. Modern brain imaging methodologies have augmented the detection ratio of brain tumor. In the past few years, a lot of research has been carried out for computer-aided diagnosis of human brain tumor to achieve 100% diagnosis accuracy. The focus of this research is on early diagnosis of brain tumor via Convolution Neural Network (CNN) to enhance state-of-the-art diagnosis accuracy. The proposed CNN is trained on a benchmark dataset, BR35H, containing brain tumor MRIs. The performance and sustainability of the model is evaluated on six different datasets, i.e., BMI-I, BTI, BMI-II, BTS, BMI-III, and BD-BT. To improve the performance of the model and to make it sustainable for totally unseen data, different geometric data augmentation techniques, along with statistical standardization, are employed. The proposed CNN-based CAD system for brain tumor diagnosis performs better than other systems by achieving an average accuracy of around 98.8% and a specificity of around 0.99. It also reveals 100% correct diagnosis for two brain MRI datasets, i.e., BTS and BD-BT. The performance of the proposed system is also compared with the other existing systems, and the analysis reveals that the proposed system outperforms all of them.

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来源期刊
CiteScore
12.00
自引率
0.00%
发文量
11
审稿时长
20 weeks
期刊介绍: The International Journal of Biomedical Imaging is managed by a board of editors comprising internationally renowned active researchers. The journal is freely accessible online and also offered for purchase in print format. It employs a web-based review system to ensure swift turnaround times while maintaining high standards. In addition to regular issues, special issues are organized by guest editors. The subject areas covered include (but are not limited to): Digital radiography and tomosynthesis X-ray computed tomography (CT) Magnetic resonance imaging (MRI) Single photon emission computed tomography (SPECT) Positron emission tomography (PET) Ultrasound imaging Diffuse optical tomography, coherence, fluorescence, bioluminescence tomography, impedance tomography Neutron imaging for biomedical applications Magnetic and optical spectroscopy, and optical biopsy Optical, electron, scanning tunneling/atomic force microscopy Small animal imaging Functional, cellular, and molecular imaging Imaging assays for screening and molecular analysis Microarray image analysis and bioinformatics Emerging biomedical imaging techniques Imaging modality fusion Biomedical imaging instrumentation Biomedical image processing, pattern recognition, and analysis Biomedical image visualization, compression, transmission, and storage Imaging and modeling related to systems biology and systems biomedicine Applied mathematics, applied physics, and chemistry related to biomedical imaging Grid-enabling technology for biomedical imaging and informatics
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