迷失在翻译中?超越性别在动物研究中的生物学变量。

IF 2.5 2区 医学 Q2 HEALTH POLICY & SERVICES Health Sociology Review Pub Date : 2021-11-01 Epub Date: 2021-08-27 DOI:10.1080/14461242.2021.1969981
Madeleine Pape
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引用次数: 5

摘要

在这篇文章中,我发展了一种女权主义的后人文主义的生物医学政策制定,作为一种物质话语干预,塑造了科学实验室中现象的出现。背景是美国生物医学,美国国立卫生研究院最近的一项政策要求在基础研究和临床前研究中考虑性别。这项名为“性别作为生物变量”(SABV)的任务将细胞系和动物模型配置为推进生物医学研究中性别平等项目的下一个前沿领域。鉴于性别和社会性别越来越被认为对人类健康和疾病具有复杂、纠缠和动态的影响,实验动物对它们试图加入这种监管干预的反应如何?通过对这一政策领域的定性分析,我展示了实验动物是如何揭示性别的特定环境特征的,它的多样性和难以捉摸的所谓的生物变量,以及需要大量的工作来支持性别的人类意识形态作为一种普遍的跨物种形式的二元差异。我认为,虽然监管干预限制了重要的模式,但它们也作为一种代理的开放,在这种开放中,实验动物可以“放松”并重新配置对知识的追求,特别是在与差异和健康有关的方面。
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Lost in translation? Beyond sex as a biological variable in animal research.

In this article, I develop a feminist posthumanist account of biomedical policymaking as a material-discursive intervention that shapes the emergence of phenomena in the scientific laboratory. The setting is United States (U.S.) biomedicine, where a recent policy of the National Institutes of Health has mandated the consideration of sex in basic and preclinical research. Called Sex as a Biological Variable (SABV), the mandate configures cell lines and animal models as the next frontier in the project of advancing gender equity in biomedical research. Given sex and gender are increasingly recognised as having complex, entangled, and dynamic effects on human health and illness, how do laboratory animals respond to their attempted enrolment in this regulatory intervention? Through a qualitative analysis of this policy domain, I show how laboratory animals reveal the context-specific character of sex, its multiplicity and elusiveness as a so-called biological variable, and the considerable work needed to shore up human ideologies of sex as a pervasive cross-species form of binary difference. I suggest that while regulatory interventions constrain patterns of mattering, they also serve as agential openings in which laboratory animals can 'kick back' and reconfigure the pursuit of knowledge, particularly as it relates to difference and health.

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来源期刊
CiteScore
7.50
自引率
0.00%
发文量
14
期刊介绍: An international, scholarly peer-reviewed journal, Health Sociology Review explores the contribution of sociology and sociological research methods to understanding health and illness; to health policy, promotion and practice; and to equity, social justice, social policy and social work. Health Sociology Review is published in association with The Australian Sociological Association (TASA) under the editorship of Eileen Willis. Health Sociology Review publishes original theoretical and research articles, literature reviews, special issues, symposia, commentaries and book reviews.
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