机构采用围手术期血液管理方案可显著降低初次全髋关节置换术患者的输血率。

IF 1.2 Q3 ORTHOPEDICS Advances in Orthopedics Pub Date : 2021-09-30 eCollection Date: 2021-01-01 DOI:10.1155/2021/2235600
Hargita Dömötör, Ádám L Varga, Róbert Sződy, Ferenc Tóth, Gábor Nardai
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引用次数: 0

摘要

骨科手术患者围手术期输血增加了术后并发症的数量。因此,我们引入了一种机构定制的围手术期血液管理方案(PBM),以减少初次全髋关节置换术(THR)患者的输血量。我们在两个预定的观察期进行了前后观察队列研究。登记了人口统计学和临床数据、ASA评分、实验室参数、手术过程特征和麻醉情况。同时评估围手术期输液、输液率及术后并发症等参数。第一个观察期有100名患者入组,第二个观察期有108名患者入组。尽管创伤后THR手术的比例增加了(9%对17%),但PBM方案得到了有效利用,并且观察到围手术期输血率显著降低(61%对21%)。我们的同事遵守取消术前常规低分子肝素预防(90%对16%),术中使用氨甲环酸(10%对84%),并鼓励利用我们的术后观察设施(5%对39%)。仍然需要输血的患者术前血红蛋白水平较低(129对147 g/l), ASA评分较高(ASA III: 46%对19%),术后低血压(40%对7%)、少尿(23%对5%)和感染(9%对2%)的发生率更高。我们得出结论,个体化围手术期血液管理方案成功实施,并取得了较低的输血率和较好的结果。我们的研究表明,在围手术期血液管理模式有限的国家,部分的、机构定制的PBM计划可能是合适的和有益的。
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Institutionally Adopted Perioperative Blood Management Program Significantly Decreased the Transfusion Rate of Patients Having Primary Total Hip Replacement Surgery.

Perioperative transfusion in patients undergoing orthopedic surgery increases the number of postoperative complications. Thus, we have introduced an institution-tailored perioperative blood management program (PBM) to decrease the amount of blood transfused in patients going through primary total hip replacement (THR) surgery. We have conducted a before-after observational cohort study in two predetermined observational periods. Demographic and clinical data, ASA scores, laboratory parameters, features of surgical procedure, and anesthesia were registered. Parameters of perioperative fluid administration, transfusion rate, and postoperative complications were also assessed. One hundred patients in the first and 108 patients in the second observational period were enrolled. Eventhough the ratio of posttraumatic THR procedures increased (9% vs. 17%), the PBM protocol has been utilized effectively and a significant decrease in perioperative blood transfusion rate has been observed (61% vs. 21%). The abolishment of routine preoperative LMWH prophylaxis (90% vs. 16%), intraoperative use of tranexamic acid (10% vs. 84%), and the encouraged exploitation of our postoperative observational facility (5% vs. 39%) were abided by our colleagues. Patients still requiring transfusion had lower preoperative hemoglobin levels (129 vs. 147 g/l), scored higher in ASA (ASA III: 46% vs. 19%), and more often presented postoperative hypotension (40% vs. 7%), oliguria (23% vs. 5%), and infections (9% vs. 2%). We conclude that the individualized perioperative blood management protocol was successfully implemented and yielded a lower transfusion rate and better outcomes. Our study suggests that a partial, institution-tailored PBM program may be suitable and beneficial in countries where the modalities of perioperative blood management are limited.

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来源期刊
CiteScore
2.40
自引率
0.00%
发文量
36
审稿时长
21 weeks
期刊介绍: Advances in Orthopedics is a peer-reviewed, Open Access journal that provides a forum for orthopaedics working on improving the quality of orthopedic health care. The journal publishes original research articles, review articles, and clinical studies related to arthroplasty, hand surgery, limb reconstruction, pediatric orthopaedics, sports medicine, trauma, spinal deformities, and orthopaedic oncology.
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