应用深度吸气屏气减少胃剂量的立体定向放疗技术用于心脏放射消融。

IF 1.8 Q3 ONCOLOGY Radiation Oncology Journal Pub Date : 2021-09-01 Epub Date: 2021-06-16 DOI:10.3857/roj.2021.00276
Myung-Jin Cha, Phillip S Cuculich, Clifford G Robinson, Ji Hyun Chang
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引用次数: 4

摘要

目的:探讨一种新的安全的心脏放射消融术——深吸气憋气(DIBH)降低胃肠道剂量。材料与方法:为治疗左心室毗邻胃的下瘢痕引起的不间断室性心动过速(VT),进行心脏放射消融术的靶区划定及治疗方案。采用四种不同的CT扫描方案(dibh、全呼气屏气、无腹部压迫和有腹部压迫的四维CT),比较目标与胃之间的距离。结果:在所有方案中,DIBH的CT扫描显示目标与胃的距离最大,并被选为治疗方案。处方剂量为25 Gy,采用DIBH获得了满意的剂量学参数。患者经DIBH治疗成功,无急性毒性反应。结论:了解心脏放射消融术对邻近器官的潜在毒性是获得最佳疗效的关键。DIBH通过胸膈运动使心脏移动,使靶物与胃物理分离。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Tailored stereotactic radiotherapy technique using deep inspiration breath-hold to reduce stomach dose for cardiac radioablation.

Purpose: To provide a new insight on a novel safe cardiac radioablation using deep inspiration breath-hold (DIBH) to reduce gastrointestinal dose.

Materials and methods: For treating incessant ventricular tachycardia (VT) originated from left ventricle inferior scar abutting the stomach, a target delineation and treatment planning for cardiac radioablation was performed. With four different computed tomography (CT) scan protocols-DIBH, full expiration breath-hold, four-dimensional (4D) CT without and with abdominal compression, the distances between the target and the stomach were compared.

Results: Among the protocols, the CT scan with DIBH showed largest distance between the target and the stomach and selected for the treatment planning. The prescribed dose was 25 Gy in a single fraction, and satisfactory dosimetric parameters were achieved with the DIBH. The patient was successfully treated with the DIBH, and experienced no acute toxicity.

Conclusion: To gain the best benefit from cardiac radioablation, understanding the possible toxicity in the adjacent organs is crucial. By moving the heart with thoraco-diaphragmatic movement by DIBH, the target could be physically separated from the stomach.

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来源期刊
CiteScore
3.50
自引率
4.30%
发文量
24
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