胆脂瘤术后手术部位感染伴或不伴乳突封堵,我们能学到什么?

IF 1.4 Q2 OTORHINOLARYNGOLOGY Journal of Otology Pub Date : 2022-01-01 DOI:10.1016/j.joto.2021.10.001
F.L.J. Cals MD, PhD, H.F.E. van der Toom, R.M. Metselaar, A. van Linge, M.P. van der Schroeff, R.J. Pauw
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引用次数: 2

摘要

本研究旨在描述与胆脂瘤手术相关的术后并发症的发生,并确定影响最常见并发症的因素,即术后手术部位感染(SSI)。材料与方法回顾性分析我院2013 - 2019年手术治疗的胆脂瘤病例。回顾了患者特征、围手术期和术后处理及并发症。根据是否行乳突封堵术将病例分为两组。结果共行胆脂瘤手术336例,其中乳突封堵248例。共观察到21例并发症,其中SSI最为常见(15/21)。闭塞组与未闭塞组术后并发症发生率无差异(p = 0.798),尤其是SSI数无差异(p = 0.520)。围手术期和/或术后预防性抗生素与两组SSI的发生无关。在非闭塞组中,较年轻的年龄(p = 0.015)和初次手术(p = 0.022)增加了SSI的风险。在闭塞组,使用生物活性玻璃(BAG) S53P4被确定为SSI的独立预测因子(p = 0.008, OR 5.940)。ssi是胆脂瘤手术中最常见的术后并发症。SSI的原因是多因素的,因此需要进一步的前瞻性研究来回答哪些因素可以防止胆脂瘤手术中SSI的发生。
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Postoperative surgical site infection in cholesteatoma surgery with and without mastoid obliteration, what can we learn?

Introduction

This study aims to describe the occurrence of postoperative complications related to cholesteatoma surgery and to determine factors influencing the most common complication, i.e. postoperative surgical site infection (SSI) in cases with and without mastoid obliteration.

Materials and methods

Retrospective analyses were performed on surgically treated cholesteatomas in our hospital between 2013 and 2019. Patient characteristics, peri- and postoperative management and complications were reviewed. The cases were divided into two groups based on whether mastoid obliteration was performed or not.

Results

A total of 336 cholesteatoma operations were performed, of which 248 cases received mastoid obliteration. In total 21 complications were observed, of which SSI was the most common (15/21). No difference in occurrence of any postoperative complication was seen between the obliteration and no-obliteration group (p = 0.798), especially not in the number of SSI (p = 0.520). Perioperative and/or postoperative prophylactic antibiotics were not associated to the development of an SSI in both groups. In the no-obliteration group a younger age (p = 0.015), as well as primary surgery (p = 0.022) increased the risk for SSI. In the obliteration group the use of bioactive glass (BAG) S53P4 was identified as independent predictor of SSI (p = 0.008, OR 5.940).

Discussion

SSI is the most common postoperative complication in cholesteatoma surgery. The causes of SSI are multifactorial, therefore further prospective research is needed to answer which factors can prevent the development of an SSI in cholesteatoma surgery.

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来源期刊
Journal of Otology
Journal of Otology Medicine-Otorhinolaryngology
CiteScore
2.70
自引率
0.00%
发文量
461
审稿时长
18 days
期刊介绍: Journal of Otology is an open access, peer-reviewed journal that publishes research findings from disciplines related to both clinical and basic science aspects of auditory and vestibular system and diseases of the ear. This journal welcomes submissions describing original experimental research that may improve our understanding of the mechanisms underlying problems of basic or clinical significance and treatment of patients with disorders of the auditory and vestibular systems. In addition to original papers the journal also offers invited review articles on current topics written by leading experts in the field. The journal is of primary importance for all scientists and practitioners interested in audiology, otology and neurotology, auditory neurosciences and related disciplines. Journal of Otology welcomes contributions from scholars in all countries and regions across the world.
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