Pub Date : 2024-04-01DOI: 10.1016/j.joto.2024.01.003
María Cuesta, Pedro Cobo
Tinnitus is a heterogeneous hearing disorder with no cure at present, but some treatments, such as a combination of counselling and sound therapy, can alleviate the discomfort it causes. The sound therapy efficiency depends on both the type of sound stimulus and the time of exposure. This study describes the fundamentals of a personalized sound therapy that stimulates the auditory system with either continuous or sequential sounds whose spectra are adjusted to the hearing levels of the participants. This sound therapy is called Enriched Acoustic Environment and is assessed in a sample of 137 participants with tinnitus. Tinnitus-related distress relief was clinically relevant and statistically significant for 90% of these patients. This was quantified as a mean decrease of 24.3 points on the Tinnitus Handicap Inventory. 31% of participants were treated with sequential stimuli and achieved greater relief of distress (29.4 points on their Tinnitus Handicap Inventory score) compared to those treated with continuous sound (69%). According to these results, sequential sound seems to be optimal compared to continuous sound.
{"title":"Enriched Acoustic Environment as a customized treatment for tinnitus: A non-controlled longitudinal study","authors":"María Cuesta, Pedro Cobo","doi":"10.1016/j.joto.2024.01.003","DOIUrl":"10.1016/j.joto.2024.01.003","url":null,"abstract":"<div><div>Tinnitus is a heterogeneous hearing disorder with no cure at present, but some treatments, such as a combination of counselling and sound therapy, can alleviate the discomfort it causes. The sound therapy efficiency depends on both the type of sound stimulus and the time of exposure. This study describes the fundamentals of a personalized sound therapy that stimulates the auditory system with either continuous or sequential sounds whose spectra are adjusted to the hearing levels of the participants. This sound therapy is called Enriched Acoustic Environment and is assessed in a sample of 137 participants with tinnitus. Tinnitus-related distress relief was clinically relevant and statistically significant for 90% of these patients. This was quantified as a mean decrease of 24.3 points on the Tinnitus Handicap Inventory. 31% of participants were treated with sequential stimuli and achieved greater relief of distress (29.4 points on their Tinnitus Handicap Inventory score) compared to those treated with continuous sound (69%). According to these results, sequential sound seems to be optimal compared to continuous sound.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 63-71"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139454961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.joto.2024.04.001
Juha T. Silvola , Saku T. Sinkkonen
Objective
Assess the long-term outcome of pediatric myringoplasty.
Methods
Tympanoplasty type I, myringoplasty, was performed on 85 children (91 consecutive operations, 74 primary and 17 revisions) under 16 years of age. The perforations were sequela either to acute or chronic inflammatory middle ear disease. Medial grafting technique was employed with temporalis fascia. Adenoidectomy was performed earlier on all but five children. The preoperative observation period exceeded one year for all patients. The mean follow-up was 5.4 (SD 3.6) years.
Results
The long-term graft take rate was 84% for primary myringoplasty, and 53% for revision operations. The re-perforations were associated with postoperative discharge, subtotal or total perforation and revision surgery. In the cohort, sixty ears (66%) were completely healthy (intact tympanic membrane in normal position without adhesions and with good mobility) after follow-up. Spontaneous healing took place in 37% after re-perforation. The preoperative ventilation tube treatment did not affect the outcome and there were no differences between age groups. Preoperative sonotubometry or Valsalva test results did not correlate with outcome. Four ears needed a ventilation tube during the follow-up due to poor ventilation. The mean pure tone thresholds improved significantly after operation.
Conclusions
Myringoplasty in children is a reliable procedure without age restrictions. One year of preoperative observation excludes most unstable ears, and high tendency of spontaneous healing after re-perforation suggests the need for a lengthy follow-up before revision surgery.
{"title":"Primary and revision myringoplasty in children: Long-term outcome and analysis of the factors influencing the results","authors":"Juha T. Silvola , Saku T. Sinkkonen","doi":"10.1016/j.joto.2024.04.001","DOIUrl":"10.1016/j.joto.2024.04.001","url":null,"abstract":"<div><h3>Objective</h3><div>Assess the long-term outcome of pediatric myringoplasty.</div></div><div><h3>Methods</h3><div>Tympanoplasty type I, myringoplasty, was performed on 85 children (91 consecutive operations, 74 primary and 17 revisions) under 16 years of age. The perforations were sequela either to acute or chronic inflammatory middle ear disease. Medial grafting technique was employed with temporalis fascia. Adenoidectomy was performed earlier on all but five children. The preoperative observation period exceeded one year for all patients. The mean follow-up was 5.4 (SD 3.6) years.</div></div><div><h3>Results</h3><div>The long-term graft take rate was 84% for primary myringoplasty, and 53% for revision operations. The re-perforations were associated with postoperative discharge, subtotal or total perforation and revision surgery. In the cohort, sixty ears (66%) were completely healthy (intact tympanic membrane in normal position without adhesions and with good mobility) after follow-up. Spontaneous healing took place in 37% after re-perforation. The preoperative ventilation tube treatment did not affect the outcome and there were no differences between age groups. Preoperative sonotubometry or Valsalva test results did not correlate with outcome. Four ears needed a ventilation tube during the follow-up due to poor ventilation. The mean pure tone thresholds improved significantly after operation.</div></div><div><h3>Conclusions</h3><div>Myringoplasty in children is a reliable procedure without age restrictions. One year of preoperative observation excludes most unstable ears, and high tendency of spontaneous healing after re-perforation suggests the need for a lengthy follow-up before revision surgery.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 85-90"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to report 9 venous thromboembolism (VTE) cases after extracranial otologic surgery and analyze the potential risk factors.
Study design
Case series.
Setting
Single tertiary-level academic center.
Methods
Totally, 9 cases of VTE were identified among adults who underwent extracranial otologic surgery at our hospital from January 2018 to December 2020. Caprini risk scores were calculated, and comprehensive preoperative, operative, and postoperative clinical data within 14 days were collected to assess the evidence of VTE.
Results
The median age of 9 patients was 64 years old. Among them, 7 (77.8%) patients presented with intramuscular vein thrombosis, 1 (11.1%) patient had deep vein thrombosis, and 1 (11.1%) patient experienced pulmonary embolism. Preoperatively, 8 (88.9%) patients had low or middle Caprini risk scores (≤4) with an average of 2.67 ± 0.47 points. The average Caprini scores for all patients were 4.44 ± 0.35 on postoperative day (POD)1 and 5.67 ± 0.64 on POD14. D-dimer levels were collected, indicating an average of 0.55 ± 0.17 mg/FEU preoperatively, 8.53 ± 3.94 mg/FEU at day 1, and 3.76 ± 0.45 mg/FEU at POD14. In postoperative period, 7 (77.8%) patients experienced vertigo/dizziness and/or head immobility/bed rest.
Conclusion
The present study highlighted that patients with low- and middle-risk of VTE undergoing otologic surgery should be also vigilant about postoperative VTE. Vertigo/dizziness and/or head immobility/bed rest in postoperative period should be considered as minor risk factors for developing VTE in patients undergoing extracranial otologic surgery. Conducting perioperative assessments, including Caprini risk score evaluation, D-dimer testing, and venous ultrasound of lower extremities, is recommended to ensure patients’ safety.
{"title":"Post-operative venous thromboembolism in patients after extracranial otologic surgery: A case series","authors":"Davit Mazmanyan , Rongrong Zhu , Juanjuan Gao , Yu Yang , Jiake Zhong , Junyan Chen , Haijin Yi , Weiwei Wu","doi":"10.1016/j.joto.2024.01.001","DOIUrl":"10.1016/j.joto.2024.01.001","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to report 9 venous thromboembolism (VTE) cases after extracranial otologic surgery and analyze the potential risk factors.</div></div><div><h3>Study design</h3><div>Case series.</div></div><div><h3>Setting</h3><div>Single tertiary-level academic center.</div></div><div><h3>Methods</h3><div>Totally, 9 cases of VTE were identified among adults who underwent extracranial otologic surgery at our hospital from January 2018 to December 2020. Caprini risk scores were calculated, and comprehensive preoperative, operative, and postoperative clinical data within 14 days were collected to assess the evidence of VTE.</div></div><div><h3>Results</h3><div>The median age of 9 patients was 64 years old. Among them, 7 (77.8%) patients presented with intramuscular vein thrombosis, 1 (11.1%) patient had deep vein thrombosis, and 1 (11.1%) patient experienced pulmonary embolism. Preoperatively, 8 (88.9%) patients had low or middle Caprini risk scores (≤4) with an average of 2.67 ± 0.47 points. The average Caprini scores for all patients were 4.44 ± 0.35 on postoperative day (POD)1 and 5.67 ± 0.64 on POD14. D-dimer levels were collected, indicating an average of 0.55 ± 0.17 mg/FEU preoperatively, 8.53 ± 3.94 mg/FEU at day 1, and 3.76 ± 0.45 mg/FEU at POD14. In postoperative period, 7 (77.8%) patients experienced vertigo/dizziness and/or head immobility/bed rest.</div></div><div><h3>Conclusion</h3><div>The present study highlighted that patients with low- and middle-risk of VTE undergoing otologic surgery should be also vigilant about postoperative VTE. Vertigo/dizziness and/or head immobility/bed rest in postoperative period should be considered as minor risk factors for developing VTE in patients undergoing extracranial otologic surgery. Conducting perioperative assessments, including Caprini risk score evaluation, D-dimer testing, and venous ultrasound of lower extremities, is recommended to ensure patients’ safety.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 59-62"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139454285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otosclerosis is a well-known disease which mainly affects middle-aged female patients, causing conductive or mixed hearing loss. Diagnosis is essentially made through a complete audiometric battery testing, while treatment substantially relies on stapes surgery.
In this study, we analyzed audiometric and Quality-of-Life data from 33 patients in order to refine the surgical indications (unilateral versus bilateral stapes surgery) and assess the best technique (stapedotomy versus partial stapedectomy) and timing of treatment. The original questionnaire OTOS, in the Italian language, was administered to all patients.
In this study, most of the patients were female (18/33), with a mean age of 53 years old. Both surgical techniques appear to be effective with no significant difference in post-operative Air Bone Gap. OTOS questionnaire appeared to be effective in assessing quality of life in patients treated by stapes surgery. Post-operative QoL appeared to be similar in bilaterally and unilaterally operated patients, suggesting that a contralateral intervention after effective surgery should be undertaken only if expressly requested by the patient.
{"title":"Unilateral versus bilateral stapes surgery: A comparative study on auditory outcome and quality of life","authors":"Luigi Curatoli , Vito Pontillo , Massimo Ralli , Francesca Yoshie Russo , Nicola Quaranta","doi":"10.1016/j.joto.2024.06.002","DOIUrl":"10.1016/j.joto.2024.06.002","url":null,"abstract":"<div><div>Otosclerosis is a well-known disease which mainly affects middle-aged female patients, causing conductive or mixed hearing loss. Diagnosis is essentially made through a complete audiometric battery testing, while treatment substantially relies on stapes surgery.</div><div>In this study, we analyzed audiometric and Quality-of-Life data from 33 patients in order to refine the surgical indications (unilateral versus bilateral stapes surgery) and assess the best technique (stapedotomy versus partial stapedectomy) and timing of treatment. The original questionnaire OTOS, in the Italian language, was administered to all patients.</div><div>In this study, most of the patients were female (18/33), with a mean age of 53 years old. Both surgical techniques appear to be effective with no significant difference in post-operative Air Bone Gap. OTOS questionnaire appeared to be effective in assessing quality of life in patients treated by stapes surgery. Post-operative QoL appeared to be similar in bilaterally and unilaterally operated patients, suggesting that a contralateral intervention after effective surgery should be undertaken only if expressly requested by the patient.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 91-96"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.joto.2024.02.001
Qing-Yuan Feng , Song Li , Yong-Mao Cao , Chuan-Xin Duan , Lu Ma , Dan Wu , Ze-Zhang Tao
Introduction
Cochlear implant is currently the most widely proven interventions for auditory rehabilitation for children with severe sensorineural hearing impairment. However, there are obvious limitations in these current evaluation methods. This study aims to develop an evaluation system for quantitatively evaluating the effectiveness of cochlear implants for hearing-impaired children.
Methods
A correspondence questionnaire was developed based on an initial indicator system that was developed based on the literature focused on the evaluation of cochlear implant outcomes in children. Twenty-five experts in otology, clinical audiology, rehabilitation audiology, and mental health from nine provinces in China were consulted. The degree of authority and coordination of experts and the indicators and weights of the quantitative evaluation system were analyzed. Seventy-eight children aged 3–11 years after cochlear implantation were recruited from two centers in Hubei province to evaluate the reliability and validity of the quantitative evaluation system.
Results
The opinions of experts converged after the second round of correspondence, and the coordination and authority of the expert consensus were met. The recall rate of the questionnaire was 100% for both rounds. Five secondary indicators, including auditory ability, verbal ability, behavioral assessment, learning capabilities, and quality of life, and 13 tertiary indicators were reserved for the evaluation of cochlear implant effectiveness. The weight of each indicator was calculated. The Cronbach’s α coefficient of the quantitative evaluation system based on the standardized items was 0.930, and the three extracted common factors could explain 78.86% of the total variance.
Conclusions
An expert consensus-based evaluation system that can quantitatively evaluate the effectiveness of cochlear implants in children has been developed with good reliability and validity.
{"title":"Establishment of quantitative evaluation system for cochlear implant effectiveness for hearing-impaired children","authors":"Qing-Yuan Feng , Song Li , Yong-Mao Cao , Chuan-Xin Duan , Lu Ma , Dan Wu , Ze-Zhang Tao","doi":"10.1016/j.joto.2024.02.001","DOIUrl":"10.1016/j.joto.2024.02.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Cochlear implant is currently the most widely proven interventions for auditory rehabilitation for children with severe sensorineural hearing impairment. However, there are obvious limitations in these current evaluation methods. This study aims to develop an evaluation system for quantitatively evaluating the effectiveness of cochlear implants for hearing-impaired children.</div></div><div><h3>Methods</h3><div>A correspondence questionnaire was developed based on an initial indicator system that was developed based on the literature focused on the evaluation of cochlear implant outcomes in children. Twenty-five experts in otology, clinical audiology, rehabilitation audiology, and mental health from nine provinces in China were consulted. The degree of authority and coordination of experts and the indicators and weights of the quantitative evaluation system were analyzed. Seventy-eight children aged 3–11 years after cochlear implantation were recruited from two centers in Hubei province to evaluate the reliability and validity of the quantitative evaluation system.</div></div><div><h3>Results</h3><div>The opinions of experts converged after the second round of correspondence, and the coordination and authority of the expert consensus were met. The recall rate of the questionnaire was 100% for both rounds. Five secondary indicators, including auditory ability, verbal ability, behavioral assessment, learning capabilities, and quality of life, and 13 tertiary indicators were reserved for the evaluation of cochlear implant effectiveness. The weight of each indicator was calculated. The Cronbach’s α coefficient of the quantitative evaluation system based on the standardized items was 0.930, and the three extracted common factors could explain 78.86% of the total variance.</div></div><div><h3>Conclusions</h3><div>An expert consensus-based evaluation system that can quantitatively evaluate the effectiveness of cochlear implants in children has been developed with good reliability and validity.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 77-84"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141390558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.joto.2024.03.002
Vural Akın , Mehmet Emre Sivrice , Kuyaş Hekimler Öztürk , Hasan Yasan , Mustafa Tüz , Erdoğan Okur , Yusuf Çağdaş Kumbul
Objective
The aim of this study was to examine angiotensin converting enzyme (ACE) insertion/deletion, alpha adducin, and interleukin-10 (IL-10) gene polymorphisms (GPs) in terms of both idiopathic sudden sensorineural hearing loss (ISSNHL) risk and their potential prognostic effects.
Methods
The study group consisted of 70 patients and the control group consisted of 50 patients. Venous blood samples were analyzed for relevant GPs via kompetitive allele-specific polymerase chain reaction. Age, sex, affected side, tinnitus, and vertiginous symptom status, number of days between symptom onset and hospital admission, pure tone audiometry results at admission and after treatment were included in the study. Data were compared statistically.
Results
The D allele of ACE insertion/deletion GP was significantly more frequent in patients with ISSNHL than in the control group (p = 0.032). II genotype was associated with a reduced risk of ISSNHL (p = 0.036). The amount of hearing loss was significantly higher in patients with the TT genotype (p = 0.027) and T allele of the IL-10 GP (p = 0.035) than in the patients without this allele. Severe hearing loss was a poor prognostic factor (p = 0.008).
Conclusions
The D allele of ACE insertion/deletion GP may be involved in the ISSNHL etiology. Due to the association of this allele with occlusive vascular pathologies, ischemia is believed to be a common pathway in the etiopathogenesis of ISSNHL.
{"title":"Evaluation of angiotensin converting enzyme insertion/deletion, alpha adducin (ADD1) G460W, and IL-10 gene polymorphisms, and determination of prognostic effects in idiopathic sudden sensorineural hearing loss","authors":"Vural Akın , Mehmet Emre Sivrice , Kuyaş Hekimler Öztürk , Hasan Yasan , Mustafa Tüz , Erdoğan Okur , Yusuf Çağdaş Kumbul","doi":"10.1016/j.joto.2024.03.002","DOIUrl":"10.1016/j.joto.2024.03.002","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to examine angiotensin converting enzyme (ACE) insertion/deletion, alpha adducin, and interleukin-10 (IL-10) gene polymorphisms (GPs) in terms of both idiopathic sudden sensorineural hearing loss (ISSNHL) risk and their potential prognostic effects.</div></div><div><h3>Methods</h3><div>The study group consisted of 70 patients and the control group consisted of 50 patients. Venous blood samples were analyzed for relevant GPs via kompetitive allele-specific polymerase chain reaction. Age, sex, affected side, tinnitus, and vertiginous symptom status, number of days between symptom onset and hospital admission, pure tone audiometry results at admission and after treatment were included in the study. Data were compared statistically.</div></div><div><h3>Results</h3><div>The D allele of ACE insertion/deletion GP was significantly more frequent in patients with ISSNHL than in the control group (p = 0.032). II genotype was associated with a reduced risk of ISSNHL (p = 0.036). The amount of hearing loss was significantly higher in patients with the TT genotype (p = 0.027) and T allele of the IL-10 GP (p = 0.035) than in the patients without this allele. Severe hearing loss was a poor prognostic factor (p = 0.008).</div></div><div><h3>Conclusions</h3><div>The D allele of ACE insertion/deletion GP may be involved in the ISSNHL etiology. Due to the association of this allele with occlusive vascular pathologies, ischemia is believed to be a common pathway in the etiopathogenesis of ISSNHL.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 97-105"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.joto.2024.07.003
Danyang Li , Hongyang Wang , Yiming Li , Yang Cao , Kaili Wu , Qiuju Wang
Objective
To make an overview of global research trends in the etiology of auditory neuropathy (AN) over the past 30 years using a bibliometric approach.
Methods
Bibliometric analyses were conducted by GraphPad Prism 9.0, Citespace 6.2.R2, and an online analysis platform to analyze and visualize publications related to etiology of AN from the Web of Science Core Collection (WoSCC) database from 1996 to 2022. Additionally, genetic factors in human AN were analyzed.
Results
In total, 604 original articles and reviews related to the etiology of AN from the WoSCC were included for bibliometric analysis. The results showed that annual publications and trend on etiology of AN increased linearly from 2000. Among them, the United States and China published nearly 400 records (40.32%). From the 604 records, a total of 752 keywords and 10 clustered network maps were extracted by Citespace, and ‘mutations’ was among the top 10 keywords. Analysis of genetic factors found that more than 30 genes were related to AN, and the latest burst occurred in 2022.
Conclusion
The bibliometric analysis mapped the global research trends and analyzed hotspots for future. The results indicated that the annual publications increased linearly from 2000. Notably, there was a burst in genetic factors in 2022, which identified that genetic factor would remain a focus of future research.
目的利用文献计量学方法对近30年来全球听神经病变（an）病因学的研究趋势进行综述。方法采用GraphPad Prism 9.0、Citespace 6.2进行文献计量学分析。R2，以及一个在线分析平台，用于分析和可视化Web of Science Core Collection （WoSCC）数据库中1996年至2022年an病因学相关的出版物。此外，还分析了人类AN的遗传因素。结果共纳入wscc上604篇与AN病因相关的原创文章和综述进行文献计量学分析。结果表明，自2000年以来，有关AN病因学的年度出版物和趋势呈线性增长。其中，美国和中国发布了近400条记录（40.32%）。从604条记录中，Citespace共提取了752个关键词和10个聚类网络图，其中“突变”是排名前10的关键词之一。遗传因素分析发现，有30多个基因与AN有关，最近一次爆发发生在2022年。结论文献计量学分析绘制了全球研究趋势，分析了未来研究热点。结果表明，自2000年以来，年度出版物呈线性增长。值得注意的是，遗传因素在2022年出现了爆发，这表明遗传因素仍将是未来研究的重点。
{"title":"Current trends and hotspots of etiology of auditory neuropathy in the past 30 years: A bibliometric analysis","authors":"Danyang Li , Hongyang Wang , Yiming Li , Yang Cao , Kaili Wu , Qiuju Wang","doi":"10.1016/j.joto.2024.07.003","DOIUrl":"10.1016/j.joto.2024.07.003","url":null,"abstract":"<div><h3>Objective</h3><div>To make an overview of global research trends in the etiology of auditory neuropathy (AN) over the past 30 years using a bibliometric approach.</div></div><div><h3>Methods</h3><div>Bibliometric analyses were conducted by GraphPad Prism 9.0, Citespace 6.2.R2, and an online analysis platform to analyze and visualize publications related to etiology of AN from the Web of Science Core Collection (WoSCC) database from 1996 to 2022. Additionally, genetic factors in human AN were analyzed.</div></div><div><h3>Results</h3><div>In total, 604 original articles and reviews related to the etiology of AN from the WoSCC were included for bibliometric analysis. The results showed that annual publications and trend on etiology of AN increased linearly from 2000. Among them, the United States and China published nearly 400 records (40.32%). From the 604 records, a total of 752 keywords and 10 clustered network maps were extracted by Citespace, and ‘mutations’ was among the top 10 keywords. Analysis of genetic factors found that more than 30 genes were related to AN, and the latest burst occurred in 2022.</div></div><div><h3>Conclusion</h3><div>The bibliometric analysis mapped the global research trends and analyzed hotspots for future. The results indicated that the annual publications increased linearly from 2000. Notably, there was a burst in genetic factors in 2022, which identified that genetic factor would remain a focus of future research.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 113-119"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myringoplasty aims to improve hearing and prevent otorrhea, making graft uptake rates and hearing crucial considerations. This study analyzed the factors associated with unsuccessful graft uptake and hearing improvement to guide the selection of optimal surgical approaches for myringoplasty.
Methods
We retrospectively reviewed 56 ears with chronic otitis media. All patients were followed up for >6 months after tympanic membrane closure surgery. We compared the underlay method using the transcanal approach with the inlay method using the retroauricular approach for myringoplasty in patients with chronic otitis media. The underlay and inlay methods were used for 23 and 33 ears, respectively. The primary outcomes were graft uptake rate and hearing improvement. Additionally, factors such as the location of tympanic membrane perforation, patient age, and the degree of mastoid development were evaluated.
Results
The perforation rate was high when the transcanal underlay method was employed to repair perforations in the anterior inferior quadrant. Both the underlay and inlay methods significantly improved hearing. However, the success rate of the inlay method was lower. Within the cases performed using the inlay method, outcomes tended to be poorer in older age groups. There were no significant differences in surgical success rates related to mastoid development.
Conclusion
The inlay method using the retroauricular approach is a favorable option for repairing perforations involving the anterior inferior quadrant. However, older patients presented lower rates of hearing improvement when the inlay method was used.
{"title":"Myringoplasty: A comparison of inlay and underlay techniques","authors":"Hisashi Sugimoto, Akiko Tamori, Miyako Hatano, Hiroki Hasegawa, Tomokazu Yoshizaki","doi":"10.1016/j.joto.2024.04.004","DOIUrl":"10.1016/j.joto.2024.04.004","url":null,"abstract":"<div><h3>Purpose</h3><div>Myringoplasty aims to improve hearing and prevent otorrhea, making graft uptake rates and hearing crucial considerations. This study analyzed the factors associated with unsuccessful graft uptake and hearing improvement to guide the selection of optimal surgical approaches for myringoplasty.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed 56 ears with chronic otitis media. All patients were followed up for >6 months after tympanic membrane closure surgery. We compared the underlay method using the transcanal approach with the inlay method using the retroauricular approach for myringoplasty in patients with chronic otitis media. The underlay and inlay methods were used for 23 and 33 ears, respectively. The primary outcomes were graft uptake rate and hearing improvement. Additionally, factors such as the location of tympanic membrane perforation, patient age, and the degree of mastoid development were evaluated.</div></div><div><h3>Results</h3><div>The perforation rate was high when the transcanal underlay method was employed to repair perforations in the anterior inferior quadrant. Both the underlay and inlay methods significantly improved hearing. However, the success rate of the inlay method was lower. Within the cases performed using the inlay method, outcomes tended to be poorer in older age groups. There were no significant differences in surgical success rates related to mastoid development.</div></div><div><h3>Conclusion</h3><div>The inlay method using the retroauricular approach is a favorable option for repairing perforations involving the anterior inferior quadrant. However, older patients presented lower rates of hearing improvement when the inlay method was used.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 72-76"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A longitudinal study on auditory developmental responses in very preterm, moderately preterm and late preterm infants","authors":"Jayashree Seethapathy , Prakash Boominathan , Ajith Kumar Uppunda , Binu Ninan","doi":"10.1016/j.joto.2024.05.003","DOIUrl":"10.1016/j.joto.2024.05.003","url":null,"abstract":"","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 106-112"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stapes surgery is the gold standard for managing otosclerosis. It has become increasingly appreciated to perform endoscopic ear surgery worldwide as the field of endoscopy expands. In basic terms, a stapes surgery intends to restore ossicular mobility and therefore improve sound energy transduction into the inner ear, thereby improving communication and sound amplification and bringing hearing levels back to acceptable levels. The aim of the study is to analyze surgical techniques comparing microscopic and endoscopic approaches for stapes surgery. The perspectives of Surgical Pioneers in Early Stapes Surgery and the contemporary development of surgical technology will be explored as well. Specifically, this study compiles well-documented, reliable information concerning the surgical outcomes for the endoscopic approach to stapes surgery and the results of recent studies.
{"title":"Techniques for otosclerosis surgery: Ear surgery from the microscope to the endoscope - A literature review","authors":"Luana-Maria Gherasie , Catalina Voiosu , Ricardo Bartel , Razvan Hainarosie , Irina Gabriela Ionita , Maria Denisa Zica , Viorel Zainea","doi":"10.1016/j.joto.2024.04.002","DOIUrl":"10.1016/j.joto.2024.04.002","url":null,"abstract":"<div><div>Stapes surgery is the gold standard for managing otosclerosis. It has become increasingly appreciated to perform endoscopic ear surgery worldwide as the field of endoscopy expands. In basic terms, a stapes surgery intends to restore ossicular mobility and therefore improve sound energy transduction into the inner ear, thereby improving communication and sound amplification and bringing hearing levels back to acceptable levels. The aim of the study is to analyze surgical techniques comparing microscopic and endoscopic approaches for stapes surgery. The perspectives of Surgical Pioneers in Early Stapes Surgery and the contemporary development of surgical technology will be explored as well. Specifically, this study compiles well-documented, reliable information concerning the surgical outcomes for the endoscopic approach to stapes surgery and the results of recent studies.</div></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"19 2","pages":"Pages 120-126"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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