SARS-CoV-2向医院室外环境的溢出

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL Journal of hazardous materials letters Pub Date : 2021-11-01 DOI:10.1016/j.hazl.2021.100027
Dayi Zhang , Xian Zhang , Yunfeng Yang , Xia Huang , Jingkun Jiang , Miao Li , Haibo Ling , Jing Li , Yi Liu , Guanghe Li , Weiwei Li , Chuan Yi , Ting Zhang , Yongzhong Jiang , Yan Xiong , Zhenyu He , Xinzi Wang , Songqiang Deng , Peng Zhao , Jiuhui Qu
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引用次数: 48

摘要

面对持续的冠状病毒传染病-2019 (COVID-19)大流行,许多研究集中在室内环境、固体表面或废水中的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)。目前尚不清楚SARS-CoV-2是否会蔓延到室外环境,并对周围的人和社区造成传播风险。在本研究中,我们通过检测武汉三家医院室外环境118份样本的病毒RNA来调查SARS-CoV-2的存在。我们在靠近接收COVID-19患者的医院部门或废水处理部门的土壤(205-550拷贝/g)、气溶胶(285 - 1,130拷贝/m3)和废水(255 - 18,744拷贝/L)中检测到SARS-CoV-2。这些发现表明,医院室外环境中存在明显的病毒外溢,可能是由患者的呼吸道飞沫或含有SARS-CoV-2的废水中的雾化颗粒引起的。相比之下,在其他地区或定期实施消毒的表面未检测到SARS-CoV-2。土壤可能通过沉积发挥病毒仓库的作用,并在很长一段时间内成为传播SARS-CoV-2的二次源。我们的研究结果首次表明,医院室外环境中存在超出预期的SARS-CoV-2传播高风险区域,需要对废水处理单元进行密封,完善卫生设施,以防止COVID-19传播风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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SARS-CoV-2 spillover into hospital outdoor environments

Facing the ongoing coronavirus infectious disease-2019 (COVID-19) pandemic, many studies focus on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in indoor environment, on solid surface or in wastewater. It remains unclear whether SARS-CoV-2 can spill over into outdoor environments and impose transmission risks to surrounding people and communities. In this study, we investigated the presence of SARS-CoV-2 by measuring viral RNA in 118 samples from outdoor environment of three hospitals in Wuhan. We detected SARS-CoV-2 in soils (205–550 copies/g), aerosols (285−1,130 copies/m3) and wastewaters (255−18,744 copies/L) in locations close to hospital departments receiving COVID-19 patients or in wastewater treatment sectors. These findings revealed a significant viral spillover in hospital outdoor environments that was possibly caused by respiratory droplets from patients or aerosolized particles from wastewater containing SARS-CoV-2. In contrast, SARS-CoV-2 was not detected in other areas or on surfaces with regular implemented disinfection. Soils may behave as viral warehouse through deposition and serve as a secondary source spreading SARS-CoV-2 for a prolonged time. For the first time, our findings demonstrate that there are high-risk areas out of expectation in hospital outdoor environments to spread SARS-CoV-2, calling for sealing of wastewater treatment unit and complete sanitation to prevent COVID-19 transmission risks.

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来源期刊
Journal of hazardous materials letters
Journal of hazardous materials letters Pollution, Health, Toxicology and Mutagenesis, Environmental Chemistry, Waste Management and Disposal, Environmental Engineering
CiteScore
10.30
自引率
0.00%
发文量
0
审稿时长
20 days
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