绵羊和山羊痘病审查:埃塞俄比亚流行病学、诊断、预防和控制措施的最新情况。

动物疾病(英文) Pub Date : 2021-01-01 Epub Date: 2021-11-15 DOI:10.1186/s44149-021-00028-2
Girma Zewdie, Getaw Derese, Belayneh Getachew, Hassen Belay, Mirtneh Akalu
{"title":"绵羊和山羊痘病审查:埃塞俄比亚流行病学、诊断、预防和控制措施的最新情况。","authors":"Girma Zewdie,&nbsp;Getaw Derese,&nbsp;Belayneh Getachew,&nbsp;Hassen Belay,&nbsp;Mirtneh Akalu","doi":"10.1186/s44149-021-00028-2","DOIUrl":null,"url":null,"abstract":"<p><p>Sheep pox, goat pox, and lumpy skin diseases are economically significant and contagious viral diseases of sheep, goats and cattle, respectively, caused by the genus <i>Capripoxvirus</i> (CaPV) of the family <i>Poxviridae</i>. Currently, CaPV infection of small ruminants (sheep and goats) has been distributed widely and are prevalent in Central Africa, the Middle East, Europe and Asia. This disease poses challenges to food production and distribution, affecting rural livelihoods in most African countries, including Ethiopia. Transmission occurs mainly by direct or indirect contact with infected animals. They cause high morbidity (75-100% in endemic areas) and mortality (10-85%). Additionally, the mortality rate can approach 100% in susceptible animals. Diagnosis largely relies on clinical symptoms, confirmed by laboratory testing using real-time PCR, electron microscopy, virus isolation, serology and histology. Control and eradication of sheep pox virus (SPPV), goat pox virus (GTPV), and lumpy skin disease (LSDV) depend on timely recognition of disease eruption, vector control, and movement restriction. To date, attenuated vaccines originating from KSGPV O-180 strains are effective and widely used in Ethiopia to control CaPV throughout the country. This vaccine strain is clinically safe to control CaPV in small ruminants but not in cattle which may be associated with insufficient vaccination coverage and the production of low-quality vaccines.</p>","PeriodicalId":69105,"journal":{"name":"动物疾病(英文)","volume":"1 1","pages":"28"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591591/pdf/","citationCount":"7","resultStr":"{\"title\":\"Review of sheep and goat pox disease: current updates on epidemiology, diagnosis, prevention and control measures in Ethiopia.\",\"authors\":\"Girma Zewdie,&nbsp;Getaw Derese,&nbsp;Belayneh Getachew,&nbsp;Hassen Belay,&nbsp;Mirtneh Akalu\",\"doi\":\"10.1186/s44149-021-00028-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Sheep pox, goat pox, and lumpy skin diseases are economically significant and contagious viral diseases of sheep, goats and cattle, respectively, caused by the genus <i>Capripoxvirus</i> (CaPV) of the family <i>Poxviridae</i>. Currently, CaPV infection of small ruminants (sheep and goats) has been distributed widely and are prevalent in Central Africa, the Middle East, Europe and Asia. This disease poses challenges to food production and distribution, affecting rural livelihoods in most African countries, including Ethiopia. Transmission occurs mainly by direct or indirect contact with infected animals. They cause high morbidity (75-100% in endemic areas) and mortality (10-85%). Additionally, the mortality rate can approach 100% in susceptible animals. Diagnosis largely relies on clinical symptoms, confirmed by laboratory testing using real-time PCR, electron microscopy, virus isolation, serology and histology. Control and eradication of sheep pox virus (SPPV), goat pox virus (GTPV), and lumpy skin disease (LSDV) depend on timely recognition of disease eruption, vector control, and movement restriction. To date, attenuated vaccines originating from KSGPV O-180 strains are effective and widely used in Ethiopia to control CaPV throughout the country. This vaccine strain is clinically safe to control CaPV in small ruminants but not in cattle which may be associated with insufficient vaccination coverage and the production of low-quality vaccines.</p>\",\"PeriodicalId\":69105,\"journal\":{\"name\":\"动物疾病(英文)\",\"volume\":\"1 1\",\"pages\":\"28\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591591/pdf/\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"动物疾病(英文)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s44149-021-00028-2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/11/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"动物疾病(英文)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s44149-021-00028-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/11/15 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7

摘要

绵羊痘、山羊痘和疙瘩皮肤病是由痘病毒科的CaPV属(CaPV)引起的绵羊、山羊和牛的具有经济意义和传染性的病毒性疾病。目前,小反刍动物(绵羊和山羊)的CaPV感染分布广泛,在中非、中东、欧洲和亚洲流行。这种疾病对粮食生产和分配构成挑战,影响到包括埃塞俄比亚在内的大多数非洲国家的农村生计。传播主要通过与受感染动物的直接或间接接触发生。它们造成高发病率(流行地区75-100%)和高死亡率(10-85%)。此外,易感动物的死亡率可接近100%。诊断在很大程度上依赖于临床症状,通过实时PCR、电子显微镜、病毒分离、血清学和组织学的实验室检测来证实。控制和根除羊痘病毒(SPPV)、山羊痘病毒(GTPV)和肿块性皮肤病(LSDV)取决于及时识别疾病爆发、媒介控制和限制运动。迄今为止,产自KSGPV O-180毒株的减毒疫苗是有效的,并在埃塞俄比亚广泛使用,以在全国范围内控制CaPV。该疫苗株在临床上对控制小反刍动物的CaPV是安全的,但在牛中却不安全,这可能与疫苗接种覆盖率不足和低质量疫苗的生产有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Review of sheep and goat pox disease: current updates on epidemiology, diagnosis, prevention and control measures in Ethiopia.

Sheep pox, goat pox, and lumpy skin diseases are economically significant and contagious viral diseases of sheep, goats and cattle, respectively, caused by the genus Capripoxvirus (CaPV) of the family Poxviridae. Currently, CaPV infection of small ruminants (sheep and goats) has been distributed widely and are prevalent in Central Africa, the Middle East, Europe and Asia. This disease poses challenges to food production and distribution, affecting rural livelihoods in most African countries, including Ethiopia. Transmission occurs mainly by direct or indirect contact with infected animals. They cause high morbidity (75-100% in endemic areas) and mortality (10-85%). Additionally, the mortality rate can approach 100% in susceptible animals. Diagnosis largely relies on clinical symptoms, confirmed by laboratory testing using real-time PCR, electron microscopy, virus isolation, serology and histology. Control and eradication of sheep pox virus (SPPV), goat pox virus (GTPV), and lumpy skin disease (LSDV) depend on timely recognition of disease eruption, vector control, and movement restriction. To date, attenuated vaccines originating from KSGPV O-180 strains are effective and widely used in Ethiopia to control CaPV throughout the country. This vaccine strain is clinically safe to control CaPV in small ruminants but not in cattle which may be associated with insufficient vaccination coverage and the production of low-quality vaccines.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.40
自引率
0.00%
发文量
0
期刊最新文献
Identification of novel serological agents for porcine deltacoronavirus infection based on the immunogenic accessory protein NS6 Biomedical knowledge graph construction of Sus scrofa and its application in anti-PRRSV traditional Chinese medicine discovery Case report: Diagnosis and treatment of a chinchilla's old radius and ulna fracture. Antibody seropositivity and endemicity of chikungunya and Zika viruses in Nigeria. Antigen epitopes of animal coronaviruses: a mini-review.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1