完整鼻窦癌伴横纹肌样特征。

IF 0.4 Q4 OTORHINOLARYNGOLOGY Case Reports in Otolaryngology Pub Date : 2021-11-18 eCollection Date: 2021-01-01 DOI:10.1155/2021/6075130
Erin Mulry, Danielle M Blake, Poornima Hegde, Todd E Falcone
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引用次数: 0

摘要

鼻窦恶性肿瘤以其预后差和组织学特征的多样性而闻名。虽然预后不良主要是由于疾病晚期,但组织学特征也起着重要作用。因此,准确的病理诊断至关重要。在这里,我们描述了一个63岁的男性慢性左侧鼻塞和左侧鼻出血,他被发现有一个很大的肿块占据了大部分鼻腔,穿过鼻咽部延伸到鼻咽部软腭表面的下方。在手术切除时,发现肿块起源于上颌窦底部,并侵蚀上颌窦内侧壁。病理诊断为ini1完整的低分化复合型癌,横纹肌样表型,肉瘤样癌和鳞状细胞癌灶出现在倒置乳头状瘤内。包括在这个报告是一个详细的描述,这两个病人的医疗过程和病理新颖的鼻窦肿瘤。我们的目的是阐明这种罕见肿瘤的复杂特征,以提高未来的诊断和促进对复杂组织学的鼻窦恶性肿瘤的前瞻性研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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INI1-Intact Sinonasal Carcinoma with Rhabdoid Features.

Sinonasal malignancies are known for their associated poor prognosis and diversity of histologic features. While poor prognosis is largely due to advanced disease at presentation, histologic features also play a significant role. Therefore, accurate pathologic diagnosis is of utmost importance. Here, we describe a 63-year-old male with chronic left-sided nasal obstruction and left-sided epistaxis who was found to have a large mass occupying most of the nasal cavity extending through the nasopharynx to just below the nasopharyngeal surface of the soft palate. During surgical excision, the mass was noted to originate from the floor of the maxillary sinus with erosion of the medial wall of the maxillary sinus. Pathology revealed a diagnosis of INI1-intact poorly differentiated composite carcinoma with rhabdoid phenotype and sarcomatoid and squamous cell carcinoma foci arising within an inverted papilloma. Included in this report is a detailed description of both the patient's medical course and this pathologically novel sinonasal neoplasm. We aim to elucidate this rare tumor's complex features in order to improve future diagnosis and stimulate prospective research on sinonasal malignancies with complex histology.

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来源期刊
Case Reports in Otolaryngology
Case Reports in Otolaryngology OTORHINOLARYNGOLOGY-
自引率
0.00%
发文量
20
审稿时长
13 weeks
期刊最新文献
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