Effects of shrimp oil on cardio-metabolic risk factors in children and adolescents.

Background: Antioxidants have beneficial effects on health. Shrimp oil has Astaxanthin and omega 3 that act as powerful antioxidants and might have anti-inflammatory effects on cardiovascular diseases. This study aims to investigate the effects of shrimp oil supplementation on cardio-metabolic risk factors in overweight and obese children and adolescents. Methods: This randomized, triple-blind, placebo-controlled clinical trial was conducted on 64 overweight and obese participants with 10-18 years of age. They were randomly assigned to receive either 500 mg shrimp oil or identical placebo that contained medium-chain triglycerides once per day for eight weeks. Dietary intake was obtained using food record questionnaire for three days at baseline and at the end of the study. Fasting blood samples were obtained at baseline and after eight weeks of intervention. Results: Overall, 53 participants completed the study; 30 subjects received shrimp oil and 23 subjects received placebo. There were no significant effects of shrimp oil on total cholesterol, triglyceride, HDL-C, LDL-C and blood pressure compared with the placebo group (p>0.05). Shrimp oil had no significant effects on body mass index, waist circumference and hip circumference compared with the placebo group (p>0.05). Conclusions: Supplementation with shrimp oil had no significant effects on improving the anthropometric measures and cardio-metabolic risk factors. Future clinical trials are needed to investigate the beneficial effects of higher doses of shrimp oil on cardio-metabolic risk factors in the pediatric age groups.