绿色合成介导的纳米颗粒及其对COVID-19后皮肤病的治疗作用

Q1 Biochemistry, Genetics and Molecular Biology Current Pharmacology Reports Pub Date : 2022-01-01 Epub Date: 2022-09-09 DOI:10.1007/s40495-022-00303-x
Nivedhitha Kabeerdass, Selvankumar Thangaswamy, Vaithilingam Mohanasrinivasan, Chandrasekaran Rajasekaran, Selvakumar Sundaram, Thajuddin Nooruddin, Maghimaa Mathanmohun
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引用次数: 4

摘要

综述目的:本文提供了关于sars -冠状病毒2的解释性稿件。副标题为:单链RNA的历史、COVID-19的内部特征、资源、COVID-19的生命周期、疾病库、COVID-19的继发感染和纳米草药。最近的研究发现:皮肤不是sars冠状病毒感染的主要目标,但它会以某种方式直接或间接地加剧皮肤上的皮疹。最近的研究表明,姜黄素介导的AgNPs在呼吸道合胞病毒(RSV)的侵入中显示出潜在的特性,阻断与病毒表面的相互作用,破坏病毒蛋白。近年来,通过分子对接研究,制备出了对COVID-19具有较强抑制作用的碘化铜花提取物(CuI-FE)。许多文章表明,绿色合成介导的纳米颗粒如银、金、锌、铜、铁、二氧化钛、硒和镉具有很高的抗病毒活性。摘要:抗氧化、抗病毒、抗炎、富含抗蜂群的植物介导的纳米颗粒合成可能是治疗由sars -冠状病毒2型引起的皮肤病(病毒性临床症状为瘙痒、荨麻疹、皮疹、丘疹、牛皮癣和炎症)和由COVID-19引起的(非病毒性临床症状为压力性荨麻疹、接触性皮炎和痤疮)的另一种改善、经济、环保的药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Green Synthesis-Mediated Nanoparticles and Their Curative Character Against Post COVID-19 Skin Diseases.

Purpose of review: This article provides the explanatory manuscript regarding the SARS-Corona virus 2. Sub-titled as the history of single-stranded RNA, internal characters of COVID-19, resource, the life cycle of COVID-19, reservoir of the disease, secondary infections of COVID-19 and nano herbal remedy.

Recent findings: The skin is not the main target of the SARS-corona virus 2 infections but somehow directly or indirectly, it causes exacerbating eruptions on the skin. Recent research shows that curcumin-mediated synthesized AgNPs show its potential character in the entry of respiratory syncytial virus (RSV), blocks interaction with the viral surface, and damages the viral protein. In modern days, molecular docking studies fabricated copper iodide flower extract (CuI-FE) which shows tough inhibitory action against COVID-19. Many articles show green synthesis-mediated nanoparticles like silver, gold, zinc, copper, iron, titanium dioxide, selenium, and cadmium which possess high anti-viricidal activity.

Summary: The anti-oxidant, anti-viral, anti-inflammatory, anti-hive rich plant-mediated nanoparticle synthesis might be an alternative betterment, cost-effective, and eco-friendly medication for the skin disease caused by SARS-corona virus 2 (the viral clinical signs are itchy, hives, rashes, papules, psoriasis, and inflammation) and (non-viral clinical signs-pressure urticaria, contact dermatitis, and acne) that occurred as the result of COVID-19.

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来源期刊
Current Pharmacology Reports
Current Pharmacology Reports Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
9.30
自引率
0.00%
发文量
35
期刊介绍: Current Pharmacology Reports will: publish cutting-edge reviews on subjects pertinent to all aspects of pharmacology, including drug discovery and development.provide incisive, insightful, and balanced contributions from international leading experts.interest a wide readership of basic scientists and translational investigators in academia and in industry. The Current Pharmacology Reports journal accomplishes its goal by appointing international authorities to serve as Section Editors in key subject areas, such as: epigenetics and epigenomics, chemoinformatics and rational drug design and target discovery, drug delivery and biomaterial, pharmacogenomics and molecular targets and biomarkers, chemical/drug/molecular toxicology, absorption, distribution, metabolism and elimination (ADME), pharmacokinetics (PK) and pharmacodynamics (PD), Modeling & Simulation (M&S) and pharmacometrics, and other related topics in pharmacology including neurology/central nervous system (CNS), cardiovascular, metabolic diseases, cancer, among others. Section Editors for Current Pharmacology Reports select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided. This journal publishes on a bi-monthly schedule.Please submit here: https://www.editorialmanager.com/phar/default.aspx
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