{"title":"神经性厌食症患者边缘型人格障碍的三个临床指标:试点研究","authors":"M. Danon , P. Duriez , P. Gorwood","doi":"10.1016/j.encep.2022.09.006","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>Co-occurrence of Anorexia Nervosa (AN) and borderline personality disorder (BPD) is frequent (8%–40%) and associated with specificities that impact the treatment process. Lifetime history of suicide attempt (HAS), substance use disorder (SUD) and the binge-purging subtype (B-P) might be good markers of such comorbidity. We made the hypothesis that in patients with AN, the presence of HAS, SUD and B-P have sufficient predictive power to efficiently detect an associated BPD comorbidity.</p></div><div><h3>Methods</h3><p>After a case report analysis on a pilot sample of 119 patients with AN, we performed a cross-sectional analysis on a confirmatory sample of 84 patients with AN in a single center specialized in eating disorders systematically assessing HAS, SUD, B-P and BPD using the Mini International Neuropsychiatric Interview for DSM-5 and the Diagnostic Interview for Borderline (DIB-R).</p></div><div><h3>Results</h3><p>B-P had a 100% negative predictive value, and the combination of SUD plus HAS had a 100% positive predictive value. On a quantitative level, B-P, HAS and SUD were independent explanatory factors of the DIB-R total score.</p></div><div><h3>Conclusions</h3><p>The main limitations were the low number of patients, the single center analyses, the potential overlapping of assessments and the fact that data were exclusively declarative. In this study, every patient with B-P, SUD and HAS had been diagnosed with BPD.</p></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Three clinical indicators of borderline personality disorder in anorexia nervosa: A pilot study\",\"authors\":\"M. Danon , P. Duriez , P. Gorwood\",\"doi\":\"10.1016/j.encep.2022.09.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p>Co-occurrence of Anorexia Nervosa (AN) and borderline personality disorder (BPD) is frequent (8%–40%) and associated with specificities that impact the treatment process. Lifetime history of suicide attempt (HAS), substance use disorder (SUD) and the binge-purging subtype (B-P) might be good markers of such comorbidity. We made the hypothesis that in patients with AN, the presence of HAS, SUD and B-P have sufficient predictive power to efficiently detect an associated BPD comorbidity.</p></div><div><h3>Methods</h3><p>After a case report analysis on a pilot sample of 119 patients with AN, we performed a cross-sectional analysis on a confirmatory sample of 84 patients with AN in a single center specialized in eating disorders systematically assessing HAS, SUD, B-P and BPD using the Mini International Neuropsychiatric Interview for DSM-5 and the Diagnostic Interview for Borderline (DIB-R).</p></div><div><h3>Results</h3><p>B-P had a 100% negative predictive value, and the combination of SUD plus HAS had a 100% positive predictive value. On a quantitative level, B-P, HAS and SUD were independent explanatory factors of the DIB-R total score.</p></div><div><h3>Conclusions</h3><p>The main limitations were the low number of patients, the single center analyses, the potential overlapping of assessments and the fact that data were exclusively declarative. In this study, every patient with B-P, SUD and HAS had been diagnosed with BPD.</p></div>\",\"PeriodicalId\":51042,\"journal\":{\"name\":\"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S001370062200238X\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S001370062200238X","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
摘要
目标神经性厌食症(AN)和边缘型人格障碍(BPD)的并发率很高(8%-40%),并且与影响治疗过程的特异性有关。终生自杀未遂(HAS)史、药物使用障碍(SUD)和暴饮暴食亚型(B-P)可能是此类合并症的良好标记。我们假设,在自闭症患者中,HAS、SUD 和 B-P 的存在具有足够的预测力,可以有效地检测出相关的 BPD 合并症。方法在对119名AN患者的试验样本进行病例报告分析后,我们在一个专门研究进食障碍的中心对84名AN患者的确证样本进行了横断面分析,并使用DSM-5迷你国际神经精神访谈(Mini International Neuropsychiatric Interview for DSM-5)和边缘型诊断访谈(DIB-R)对HAS、SUD、B-P和BPD进行了系统评估。在定量层面上,B-P、HAS 和 SUD 是 DIB-R 总分的独立解释因素。结论主要局限性在于患者人数较少、单中心分析、评估可能重叠以及数据完全是陈述性的。在这项研究中,所有患有B-P、SUD和HAS的患者都被诊断为BPD。
Three clinical indicators of borderline personality disorder in anorexia nervosa: A pilot study
Objectives
Co-occurrence of Anorexia Nervosa (AN) and borderline personality disorder (BPD) is frequent (8%–40%) and associated with specificities that impact the treatment process. Lifetime history of suicide attempt (HAS), substance use disorder (SUD) and the binge-purging subtype (B-P) might be good markers of such comorbidity. We made the hypothesis that in patients with AN, the presence of HAS, SUD and B-P have sufficient predictive power to efficiently detect an associated BPD comorbidity.
Methods
After a case report analysis on a pilot sample of 119 patients with AN, we performed a cross-sectional analysis on a confirmatory sample of 84 patients with AN in a single center specialized in eating disorders systematically assessing HAS, SUD, B-P and BPD using the Mini International Neuropsychiatric Interview for DSM-5 and the Diagnostic Interview for Borderline (DIB-R).
Results
B-P had a 100% negative predictive value, and the combination of SUD plus HAS had a 100% positive predictive value. On a quantitative level, B-P, HAS and SUD were independent explanatory factors of the DIB-R total score.
Conclusions
The main limitations were the low number of patients, the single center analyses, the potential overlapping of assessments and the fact that data were exclusively declarative. In this study, every patient with B-P, SUD and HAS had been diagnosed with BPD.
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