Pub Date : 2025-12-20DOI: 10.1016/j.encep.2025.09.007
Marwa Zrelli, Karim Souabni, Pierre De Maricourt, Mickaël Amagat, Raphaël Gaillard, Sarah Smadja, Fabien Vinckier, Françoise Tomberli, Aurélien Mazeraud, Philippe Domenech, Moussa A Chalah
Introduction: Electroconvulsive therapy (ECT) is an effective and widely used treatment for managing severe and/or resistant psychiatric disorders. Historically, the bitemporal setup (BT) and the age-based dosing method (ABM) have been the most common approaches. However, more recent practices, including the titration method (TM), right unilateral (RUL) electrode placement, and pulse width reduction, appear to have comparable efficacy and better tolerability. The primary objective of this study was to evaluate clinical outcomes before and after the implementation of these new practices at Sainte-Anne Hospital (GHU psychiatrie & neurosciences), the largest psychiatric hospital in Paris, France.
Method: This retrospective study included adult patients who underwent an acute course of ECT between December 2022 and May 2024. Clinical and sociodemographic data, stimulation parameters (electrodes placement, ABM vs. TM, charge difference between first and last session), and seizure characteristics (seizure duration and postictal suppression during first and last session) were collected from medical records. Data were compared and analyzed before and after the implementation of the new practices and according to the dosing method (ABM vs. TM). For treatments with TM the administered charge determined by the TM was also compared with the theoretical charge determined by ABM. As not all data followed a normal distribution, comparisons of quantitative data were made using the Mann-Whitney or Kruskal-Wallis test. Categorical data were compared using Chi2 test.
Results: Data from 75 patients were included, of whom 72 completed the course of ECT and were included in the analysis of efficacy and tolerability. Compared with the previous practices, the new practices resulted in a significant reduction in charge increase between the first and the last session (P<0.01) and a trend toward less frequently perceived memory disturbances (-21%, P<0.10), with no significant differences in sociodemographic data or seizure characteristics (P>0.05). There was a trend towards more full responders with the new practices (+15%), albeit the difference was statistically non-significant. Compared with ABM, TM resulted in a significant reduction in charge difference (P<0.001) and a trend toward less perceived memory disturbances (-23%, P<0.10) with no significant differences in other variables (P>0.05). In patients who received ECT with the TM, the administered charge was significantly lower than the theoretical charge (P<0.01).
Conclusion: The new ECT practices improve tolerability, especially regarding memory, while maintaining clinical efficacy by using reduced electrical charges. These findings highlight the importance of personalizing ECT protocols to optimize tolerability without compromising efficacy.
简介:电休克疗法(ECT)是一种有效且广泛用于治疗严重和/或顽固性精神疾病的治疗方法。从历史上看,双时间设置(BT)和基于年龄的给药方法(ABM)是最常用的方法。然而,最近的实践,包括滴定法(TM),右侧单侧(RUL)电极放置和脉宽减小,似乎具有相当的疗效和更好的耐受性。本研究的主要目的是评估在法国巴黎最大的精神病院圣安妮医院(GHU精神病学和神经科学)实施这些新做法之前和之后的临床结果。方法:这项回顾性研究纳入了2022年12月至2024年5月期间接受ECT急性疗程的成年患者。从医疗记录中收集临床和社会人口学数据、刺激参数(电极放置、ABM与TM、第一次和最后一次的电荷差异)和癫痫发作特征(第一次和最后一次的癫痫发作持续时间和电位抑制)。根据给药方法(ABM vs. TM)对新做法实施前后的数据进行比较和分析。用TM处理时,TM测定的给药电荷与ABM测定的理论电荷也进行了比较。由于并非所有数据都服从正态分布,所以定量数据的比较采用Mann-Whitney或Kruskal-Wallis检验。分类资料比较采用Chi2检验。结果:纳入75例患者的数据,其中72例完成了ECT疗程,并纳入疗效和耐受性分析。与以前的做法相比,新做法导致第一次和最后一次的电荷增加显著减少(P0.05)。采用新方法的患者有更多完全应答者的趋势(+15%),尽管差异在统计学上不显著。与ABM相比,TM显著降低了电荷差(P0.05)。在接受电痉挛疗法的患者中,施用的电荷明显低于理论电荷(结论:新的电痉挛疗法提高了耐受性,特别是在记忆方面,同时通过减少电荷保持了临床疗效。这些发现强调了个性化ECT方案在不影响疗效的情况下优化耐受性的重要性。
{"title":"Evolving electroconvulsive therapy practices at a French psychiatric hospital: A retrospective study.","authors":"Marwa Zrelli, Karim Souabni, Pierre De Maricourt, Mickaël Amagat, Raphaël Gaillard, Sarah Smadja, Fabien Vinckier, Françoise Tomberli, Aurélien Mazeraud, Philippe Domenech, Moussa A Chalah","doi":"10.1016/j.encep.2025.09.007","DOIUrl":"https://doi.org/10.1016/j.encep.2025.09.007","url":null,"abstract":"<p><strong>Introduction: </strong>Electroconvulsive therapy (ECT) is an effective and widely used treatment for managing severe and/or resistant psychiatric disorders. Historically, the bitemporal setup (BT) and the age-based dosing method (ABM) have been the most common approaches. However, more recent practices, including the titration method (TM), right unilateral (RUL) electrode placement, and pulse width reduction, appear to have comparable efficacy and better tolerability. The primary objective of this study was to evaluate clinical outcomes before and after the implementation of these new practices at Sainte-Anne Hospital (GHU psychiatrie & neurosciences), the largest psychiatric hospital in Paris, France.</p><p><strong>Method: </strong>This retrospective study included adult patients who underwent an acute course of ECT between December 2022 and May 2024. Clinical and sociodemographic data, stimulation parameters (electrodes placement, ABM vs. TM, charge difference between first and last session), and seizure characteristics (seizure duration and postictal suppression during first and last session) were collected from medical records. Data were compared and analyzed before and after the implementation of the new practices and according to the dosing method (ABM vs. TM). For treatments with TM the administered charge determined by the TM was also compared with the theoretical charge determined by ABM. As not all data followed a normal distribution, comparisons of quantitative data were made using the Mann-Whitney or Kruskal-Wallis test. Categorical data were compared using Chi<sup>2</sup> test.</p><p><strong>Results: </strong>Data from 75 patients were included, of whom 72 completed the course of ECT and were included in the analysis of efficacy and tolerability. Compared with the previous practices, the new practices resulted in a significant reduction in charge increase between the first and the last session (P<0.01) and a trend toward less frequently perceived memory disturbances (-21%, P<0.10), with no significant differences in sociodemographic data or seizure characteristics (P>0.05). There was a trend towards more full responders with the new practices (+15%), albeit the difference was statistically non-significant. Compared with ABM, TM resulted in a significant reduction in charge difference (P<0.001) and a trend toward less perceived memory disturbances (-23%, P<0.10) with no significant differences in other variables (P>0.05). In patients who received ECT with the TM, the administered charge was significantly lower than the theoretical charge (P<0.01).</p><p><strong>Conclusion: </strong>The new ECT practices improve tolerability, especially regarding memory, while maintaining clinical efficacy by using reduced electrical charges. These findings highlight the importance of personalizing ECT protocols to optimize tolerability without compromising efficacy.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-20DOI: 10.1016/j.encep.2025.09.010
Juan Martin Tecco, Ahmed Jérôme Romain, Robert Stanton, Arnaud Philippot, Yasser Khazaal, Bernard Dan, Moritz Bruno Petzold, Davy Vancampfort
Objective: Exercise offers trans-diagnostically numerous mental health benefits. Mental health professionals play a crucial role in prescribing exercise to their patients. However, there is limited research on exercise prescription behavior among French-speaking mental health professionals. This study aimed to translate the Exercise in Mental Illness Questionnaire (EMIQ-HP) into French, validate it cross-culturally and evaluate the psychometric properties of the translated version.
Methods: We followed guidelines for the cross-cultural adaptation of self-rating questionnaires to translate the EMIQ-HP and tested its 7-day test-retest reliability in a sample of 46 French-speaking Belgian mental health professionals. Reliability was assessed using intra-class correlations (ICC) and Cohen's kappa (κ).
Results: The items and scales of the French version of the questionnaire (EMIQ-Fr) demonstrated ICCs ranging from 0.41 to 0.77 and κ values from 0.42 to 0.71, with all items exhibiting either moderate (≥0.41) to substantial (≥0.61) 7-day test-retest reliability. ICCs for subscales ranged from 0.44 to 0.84 with scales exhibiting either moderate (≥0.41) to almost perfect (≥0.81) 7-day test-retest reliability.
Conclusions: The EMIQ-Fr is the first standardized French language questionnaire designed to assess mental health professionals' views on exercise in mental disorders. Its application in future research could enhance our understanding and support of patients with mental disorders in achieving or maintaining health-beneficial levels of exercise.
{"title":"The French version of the Exercise in Mental Illness Questionnaire (EMIQ-Fr): Translation, cross-cultural validation and psychometric properties.","authors":"Juan Martin Tecco, Ahmed Jérôme Romain, Robert Stanton, Arnaud Philippot, Yasser Khazaal, Bernard Dan, Moritz Bruno Petzold, Davy Vancampfort","doi":"10.1016/j.encep.2025.09.010","DOIUrl":"https://doi.org/10.1016/j.encep.2025.09.010","url":null,"abstract":"<p><strong>Objective: </strong>Exercise offers trans-diagnostically numerous mental health benefits. Mental health professionals play a crucial role in prescribing exercise to their patients. However, there is limited research on exercise prescription behavior among French-speaking mental health professionals. This study aimed to translate the Exercise in Mental Illness Questionnaire (EMIQ-HP) into French, validate it cross-culturally and evaluate the psychometric properties of the translated version.</p><p><strong>Methods: </strong>We followed guidelines for the cross-cultural adaptation of self-rating questionnaires to translate the EMIQ-HP and tested its 7-day test-retest reliability in a sample of 46 French-speaking Belgian mental health professionals. Reliability was assessed using intra-class correlations (ICC) and Cohen's kappa (κ).</p><p><strong>Results: </strong>The items and scales of the French version of the questionnaire (EMIQ-Fr) demonstrated ICCs ranging from 0.41 to 0.77 and κ values from 0.42 to 0.71, with all items exhibiting either moderate (≥0.41) to substantial (≥0.61) 7-day test-retest reliability. ICCs for subscales ranged from 0.44 to 0.84 with scales exhibiting either moderate (≥0.41) to almost perfect (≥0.81) 7-day test-retest reliability.</p><p><strong>Conclusions: </strong>The EMIQ-Fr is the first standardized French language questionnaire designed to assess mental health professionals' views on exercise in mental disorders. Its application in future research could enhance our understanding and support of patients with mental disorders in achieving or maintaining health-beneficial levels of exercise.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1016/j.encep.2025.09.006
Apolline C Till, Teague R Henry, Marco Scutari, Giovanni Briganti
The Conners Teacher Rating Scale revised: short (CTRS-R: S) is a widely used psychometric instrument to screen for Attention Deficit and Hyperactivity Disorder (ADHD) as well as a broader construct of abnormal child behavior. In this study, we aimed to examine the network structure of abnormal child behavior using the CTRS-R: S in a sample of 525 French-speaking primary school students from Belgium. We employed Bayesian network analysis to estimate both the 28-item network and the network with the 8 items with the highest strength centrality, using the PC algorithm and bootstrapping to estimate the figures. Our study uncovered associations between inattention symptoms and learning disorders, shedding new light on the complexity of abnormal child behavior. We also identified different network structures, revealing a fresh perspective on the underlying mechanisms of these conditions. Our findings, though preliminary, are consistent with previous research and add to the burgeoning literature on Bayesian network analysis in abnormal child behavior research. Overall, our study underscores the complexity of the construct of abnormal child behavior and the importance of considering multiple factors in screening and diagnosis, emphasizing the need for a comprehensive approach to understanding and treating these disorders.
{"title":"Abnormal Child Behavior in primary school students: A Bayesian network analysis.","authors":"Apolline C Till, Teague R Henry, Marco Scutari, Giovanni Briganti","doi":"10.1016/j.encep.2025.09.006","DOIUrl":"https://doi.org/10.1016/j.encep.2025.09.006","url":null,"abstract":"<p><p>The Conners Teacher Rating Scale revised: short (CTRS-R: S) is a widely used psychometric instrument to screen for Attention Deficit and Hyperactivity Disorder (ADHD) as well as a broader construct of abnormal child behavior. In this study, we aimed to examine the network structure of abnormal child behavior using the CTRS-R: S in a sample of 525 French-speaking primary school students from Belgium. We employed Bayesian network analysis to estimate both the 28-item network and the network with the 8 items with the highest strength centrality, using the PC algorithm and bootstrapping to estimate the figures. Our study uncovered associations between inattention symptoms and learning disorders, shedding new light on the complexity of abnormal child behavior. We also identified different network structures, revealing a fresh perspective on the underlying mechanisms of these conditions. Our findings, though preliminary, are consistent with previous research and add to the burgeoning literature on Bayesian network analysis in abnormal child behavior research. Overall, our study underscores the complexity of the construct of abnormal child behavior and the importance of considering multiple factors in screening and diagnosis, emphasizing the need for a comprehensive approach to understanding and treating these disorders.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1016/j.encep.2025.09.008
Thomas Fovet, Marion Eck, Béatrice Carton, Marc Fédèle, Mathieu Lacambre, Anne-Hélène Moncany, Catherine Paulet, Jean-Louis Senon, Pierre Thomas, Pascale Giravalli
In March 2025 the French Minister of Justice announced that, beginning at the end of July 2025, the prisons of Vendin-le-Vieil and Condé-sur-Sarthe would host approximately 200 individuals convicted of drug trafficking within newly established units specifically designed to address organized crime. Incarceration conditions in these high-security facilities will be extremely strict, with the explicit goal of severing incarcerated people's contact with the outside world. The detrimental effects of solitary confinement on incarcerated people's health are well-documented, and numerous international conventions and treaties stipulate that such measures should be used only in exceptional circumstances, as a last resort, and for the shortest time possible. This article examines the role of healthcare professionals within these high-security units. To what extent can the principle of equivalence of care - according to which incarcerated individuals must receive healthcare equivalent to that provided to the general population - be upheld in this context? We address the issue of the ethical responsibility of healthcare professionals working in facilities where conditions of incarceration are known to have deleterious effects on the health of incarcerated individuals.
{"title":"[High-security prisons: How far is it possible to care people in prison?]","authors":"Thomas Fovet, Marion Eck, Béatrice Carton, Marc Fédèle, Mathieu Lacambre, Anne-Hélène Moncany, Catherine Paulet, Jean-Louis Senon, Pierre Thomas, Pascale Giravalli","doi":"10.1016/j.encep.2025.09.008","DOIUrl":"https://doi.org/10.1016/j.encep.2025.09.008","url":null,"abstract":"<p><p>In March 2025 the French Minister of Justice announced that, beginning at the end of July 2025, the prisons of Vendin-le-Vieil and Condé-sur-Sarthe would host approximately 200 individuals convicted of drug trafficking within newly established units specifically designed to address organized crime. Incarceration conditions in these high-security facilities will be extremely strict, with the explicit goal of severing incarcerated people's contact with the outside world. The detrimental effects of solitary confinement on incarcerated people's health are well-documented, and numerous international conventions and treaties stipulate that such measures should be used only in exceptional circumstances, as a last resort, and for the shortest time possible. This article examines the role of healthcare professionals within these high-security units. To what extent can the principle of equivalence of care - according to which incarcerated individuals must receive healthcare equivalent to that provided to the general population - be upheld in this context? We address the issue of the ethical responsibility of healthcare professionals working in facilities where conditions of incarceration are known to have deleterious effects on the health of incarcerated individuals.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1016/j.encep.2025.09.005
Pierre Oswald, Thierry Pham
Objective: To explore the limitations of psychiatric dangerousness assessments in Belgium, France, the UK, and the Netherlands, and to assess whether systematic and structured risk assessment, supported by enhanced forensic psychiatry skills and interdisciplinarity, could improve involuntary care decisions.
Methods: Comparative analysis of legislative frameworks (Belgian law of 26 June 1990, amended in 2024; French Public Health Code; Mental Health Act 1983; Compulsory Mental Health Care Act 2020; Wet verplichte geestelijke gezondheidszorg 2020) and assessment practices based on literature and statistical data.
Results: Compulsory measures have been strongly increasing in Belgium, France, the UK, and the Netherlands for over a decade. Subjective dangerousness assessments, based on vague legal criteria not recently revised, show significant variability in Belgium and France where structured tools are absent, unlike the UK and the Netherlands which are developing initiatives around risk assessment, notably with the HCR-20 V3 to structure decisions. These tools demonstrate validated predictive accuracy but would require essential training for implementation.
Conclusions: Implementing structured tools, combined with interdisciplinary and forensic psychiatry training inspired by the Nixon line, could reduce subjective biases, stigma, and trauma pending studies confirming their effectiveness.
{"title":"[Involuntary care: From dangerousness to risk assessment].","authors":"Pierre Oswald, Thierry Pham","doi":"10.1016/j.encep.2025.09.005","DOIUrl":"https://doi.org/10.1016/j.encep.2025.09.005","url":null,"abstract":"<p><strong>Objective: </strong>To explore the limitations of psychiatric dangerousness assessments in Belgium, France, the UK, and the Netherlands, and to assess whether systematic and structured risk assessment, supported by enhanced forensic psychiatry skills and interdisciplinarity, could improve involuntary care decisions.</p><p><strong>Methods: </strong>Comparative analysis of legislative frameworks (Belgian law of 26 June 1990, amended in 2024; French Public Health Code; Mental Health Act 1983; Compulsory Mental Health Care Act 2020; Wet verplichte geestelijke gezondheidszorg 2020) and assessment practices based on literature and statistical data.</p><p><strong>Results: </strong>Compulsory measures have been strongly increasing in Belgium, France, the UK, and the Netherlands for over a decade. Subjective dangerousness assessments, based on vague legal criteria not recently revised, show significant variability in Belgium and France where structured tools are absent, unlike the UK and the Netherlands which are developing initiatives around risk assessment, notably with the HCR-20 V3 to structure decisions. These tools demonstrate validated predictive accuracy but would require essential training for implementation.</p><p><strong>Conclusions: </strong>Implementing structured tools, combined with interdisciplinary and forensic psychiatry training inspired by the Nixon line, could reduce subjective biases, stigma, and trauma pending studies confirming their effectiveness.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1016/j.encep.2025.09.009
Chirine Fares
{"title":"The fabric of mood in mania co-occurring with substance use.","authors":"Chirine Fares","doi":"10.1016/j.encep.2025.09.009","DOIUrl":"https://doi.org/10.1016/j.encep.2025.09.009","url":null,"abstract":"","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1016/j.encep.2025.09.004
Hélène Lahaye, Anna Heniquez, Caroline Tual, Sébastien Garny de la Riviere, Xavier Benarous
Introduction: Alexithymia is a central concept in understanding the psychological vulnerability to eating disorders. Associations between alexithymia and distinct components of interoception have previously been reported in healthy individuals and those with mental health problems. From a therapeutic perspective, it is important to determine whether such associations exist for adolescents with anorexia nervosa and which domains of interoception (i.e., accuracy [IAc], awareness [IAw], and sensibility [ISe]) are concerned.
Method: A cross-sectional study was conducted on twenty 12-17-year-old hospitalized adolescent girls with restrictive anorexia nervosa (M=14years±1.59, mean BMI of 15.59). The heartbeat detection task (HBDT) assessed IAc and IAw. The Porges Body Perception Questionnaire (PBPQ) was used for ISe, the Children-Toronto Alexithymia Scale (CTAS) for alexithymia, alongside the Child Depressive Inventory (CDI) for depression, the ECAP for anxiety, and the Difficulties in Emotion Regulation Scale-Youth scale (DERS-Y) for emotional dysregulation.
Results: The error rate at the HBDT was negatively correlated with the CTAS sub score "Externally-oriented thinking" but no other CTAS sub scores or other clinical dimensions. The association between IAw and the CTAS sub-score "Externally-oriented thinking" failed to remain significant after Bonferroni correction. The PBPQ total score was positively correlated with the CDI total score and the ECAP fear sub score.
Conclusion: Among adolescents hospitalized for anorexia nervosa, the more accurate the detection of heart rate, the more frequently operative thinking was reported, while a high level of ISe was associated with anxiety and depression-related symptoms. The mechanisms underlying the relation between the discrimination of body perception and emotional processing may vary across psychiatric disorders.
{"title":"Interoceptive patterns and alexithymia in adolescents with anorexia nervosa.","authors":"Hélène Lahaye, Anna Heniquez, Caroline Tual, Sébastien Garny de la Riviere, Xavier Benarous","doi":"10.1016/j.encep.2025.09.004","DOIUrl":"https://doi.org/10.1016/j.encep.2025.09.004","url":null,"abstract":"<p><strong>Introduction: </strong>Alexithymia is a central concept in understanding the psychological vulnerability to eating disorders. Associations between alexithymia and distinct components of interoception have previously been reported in healthy individuals and those with mental health problems. From a therapeutic perspective, it is important to determine whether such associations exist for adolescents with anorexia nervosa and which domains of interoception (i.e., accuracy [IAc], awareness [IAw], and sensibility [ISe]) are concerned.</p><p><strong>Method: </strong>A cross-sectional study was conducted on twenty 12-17-year-old hospitalized adolescent girls with restrictive anorexia nervosa (M=14years±1.59, mean BMI of 15.59). The heartbeat detection task (HBDT) assessed IAc and IAw. The Porges Body Perception Questionnaire (PBPQ) was used for ISe, the Children-Toronto Alexithymia Scale (CTAS) for alexithymia, alongside the Child Depressive Inventory (CDI) for depression, the ECAP for anxiety, and the Difficulties in Emotion Regulation Scale-Youth scale (DERS-Y) for emotional dysregulation.</p><p><strong>Results: </strong>The error rate at the HBDT was negatively correlated with the CTAS sub score \"Externally-oriented thinking\" but no other CTAS sub scores or other clinical dimensions. The association between IAw and the CTAS sub-score \"Externally-oriented thinking\" failed to remain significant after Bonferroni correction. The PBPQ total score was positively correlated with the CDI total score and the ECAP fear sub score.</p><p><strong>Conclusion: </strong>Among adolescents hospitalized for anorexia nervosa, the more accurate the detection of heart rate, the more frequently operative thinking was reported, while a high level of ISe was associated with anxiety and depression-related symptoms. The mechanisms underlying the relation between the discrimination of body perception and emotional processing may vary across psychiatric disorders.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.encep.2025.06.009
Jean Belbèze , Claire Lamas , Jérôme Silva , Maurice Corcos , Marion Robin
Objective
In a context of debates on the place of complex trauma within psychiatric pathology, it is essential to accurately measure the extent of the effects of adversity across different disorders. Such studies are rare, however, because they often focus on a single diagnosis. The measurement of adversity is usually self-reported, retrospective, and usually includes a single dimension. Furthermore, at-risk family interactions and maltreatment constitute two distinct and central risk factors for both complex trauma and psychiatric disorders. Yet they are rarely studied together, nor through an overview of psychiatric disorders. This is the aim of this study, which hypothesizes that adversity is widely distributed across all the psychiatric disorders of adolescents admitted to psychiatric hospitals, and postulates that it is possible to discern distinct adversity profiles depending on the diagnosis.
Methodology
This cross-sectional analysis stems from the Family & Care study, which aims to measure various adversity factors in hospitalized adolescents aged 13 to 19 (n = 425). Data on abuse and neglect were collected by hetero-assessment using the European abuse and neglect database Child Abuse and Neglect via Minimum Data Set (CAN-via-MDS), and family interactions were measured using the At-Risk Family Interactions and Levers (ARFIL) scale, a 30-item clinical tool also rated by hetero-assessment.
Results
Among the 425 participants, the prevalence of emotional abuse was 46.1%, physical abuse 21.4%, sexual abuse 25.1% and neglect 70.5%. The psychiatric disorders measured were all associated with significant rates of childhood adversity, and different adversity profiles could be identified according to diagnosis. Trauma- and stress-related disorders accounted for only 13.4% of disorders. The latter, as well as borderline personality disorder and oppositional defiant disorder, were associated with higher scores of at-risk family interactions than the other diagnoses, highlighting the distinct influence of at-risk family dynamics independently of abuse or neglect.
Conclusion
The determinants linked to adversity cut across all the nosographic fields in child psychiatry, and support the idea that the complex trauma clinic overlaps strongly with all the usual diagnostic categories. Depending on the diagnosis, it seems possible to identify distinct adversity profiles, with borderline personality disorder appearing as one face of complex trauma among others. The Family & Care study reinforces the value of multiplying the sources of observation in clinical practice and in future research, by combining diagnostic aspects with the relational correlates of patients under psychiatric care, which represent both risk factors and essential therapeutic levers.
{"title":"Adversité, troubles psychiatriques adolescents et trauma complexe : comorbidités ou superposition ?","authors":"Jean Belbèze , Claire Lamas , Jérôme Silva , Maurice Corcos , Marion Robin","doi":"10.1016/j.encep.2025.06.009","DOIUrl":"10.1016/j.encep.2025.06.009","url":null,"abstract":"<div><h3>Objective</h3><div>In a context of debates on the place of complex trauma within psychiatric pathology, it is essential to accurately measure the extent of the effects of adversity across different disorders. Such studies are rare, however, because they often focus on a single diagnosis. The measurement of adversity is usually self-reported, retrospective, and usually includes a single dimension. Furthermore, at-risk family interactions and maltreatment constitute two distinct and central risk factors for both complex trauma and psychiatric disorders. Yet they are rarely studied together, nor through an overview of psychiatric disorders. This is the aim of this study, which hypothesizes that adversity is widely distributed across all the psychiatric disorders of adolescents admitted to psychiatric hospitals, and postulates that it is possible to discern distinct adversity profiles depending on the diagnosis.</div></div><div><h3>Methodology</h3><div>This cross-sectional analysis stems from the Family & Care study, which aims to measure various adversity factors in hospitalized adolescents aged 13 to 19 (<em>n</em> <!-->=<!--> <!-->425). Data on abuse and neglect were collected by hetero-assessment using the European abuse and neglect database Child Abuse and Neglect via Minimum Data Set (CAN-via-MDS), and family interactions were measured using the At-Risk Family Interactions and Levers (ARFIL) scale, a 30-item clinical tool also rated by hetero-assessment.</div></div><div><h3>Results</h3><div>Among the 425 participants, the prevalence of emotional abuse was 46.1%, physical abuse 21.4%, sexual abuse 25.1% and neglect 70.5%. The psychiatric disorders measured were all associated with significant rates of childhood adversity, and different adversity profiles could be identified according to diagnosis. Trauma- and stress-related disorders accounted for only 13.4% of disorders. The latter, as well as borderline personality disorder and oppositional defiant disorder, were associated with higher scores of at-risk family interactions than the other diagnoses, highlighting the distinct influence of at-risk family dynamics independently of abuse or neglect.</div></div><div><h3>Conclusion</h3><div>The determinants linked to adversity cut across all the nosographic fields in child psychiatry, and support the idea that the complex trauma clinic overlaps strongly with all the usual diagnostic categories. Depending on the diagnosis, it seems possible to identify distinct adversity profiles, with borderline personality disorder appearing as one face of complex trauma among others. The Family & Care study reinforces the value of multiplying the sources of observation in clinical practice and in future research, by combining diagnostic aspects with the relational correlates of patients under psychiatric care, which represent both risk factors and essential therapeutic levers.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 6","pages":"Pages S24-S31"},"PeriodicalIF":1.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.encep.2025.05.005
Maud Cappelletti , Aziz Essadek , Ariane Bazan
Complex post-traumatic stress disorder is a recent diagnosis with manifestations that differ from those of post-traumatic stress disorder. Persistent functional impairment is a new dimension specific to complex trauma. Some aspects of this diagnostic category which was adopted by the international classification of diseases eleventh revision are still being studied, for example, its prevalence across the world in many cultural situations where the exposure to traumatic events differ. Network analysis offers a new conceptualization of psychopathology by focusing on interactions between symptoms beyond the usual latent class approach. It makes it possible to statistically validate the international classification of diseases’ new diagnostic criteria by differentiating the manifestations of different pathologies such as intense stress exposure pathologies or borderline disorder that share symptoms. It also provides various insights into this disorder and allows us to observe sequences of appearance and evolution depending on age and type of event. While childhood trauma appears to be particularly associated with complex post-traumatic stress disorder, literature mainly highlights the long-term consequences of such childhood events in adulthood. The persistent functional impairment cluster is particularly important within complex trauma networks. This is one of the most important developmental consequences for survivors and reflects a reality perceived by clinicians. This extends to psychotherapy which turns out to be longer and more complex because of the insecurity of the relationship experienced by the traumatized person. Network analysis applied to complex trauma gives an understanding of the dynamics of the relationships between its multitude of symptoms. They can define intervention targets for mental health professionals. And they can enable coordinated multi-professional actions which is an important issue especially in multi-factorial situations such as child protection. This work explores the contributions of network analysis to the understanding of complex post-traumatic stress disorder. For this purpose, we outline the central concepts of complex trauma and its implications. In particular, the impact of recurring traumatic situations of an interpersonal nature on self-construction and the ability to create relationships. We exhibit the fundamental principles of the network approach and compare the contributions of older cross-sectional analyzes with those of longitudinal networks. Then, we provide an overview of the knowledge acquired through the application of network analysis to complex trauma, from childhood to adulthood. Finally, we discuss criticisms of this approach and propose reflections on the future of this statistical analysis method which is growing fast.
{"title":"Psychotraumatisme complexe et analyse de réseaux : de l’enfance à l’âge adulte","authors":"Maud Cappelletti , Aziz Essadek , Ariane Bazan","doi":"10.1016/j.encep.2025.05.005","DOIUrl":"10.1016/j.encep.2025.05.005","url":null,"abstract":"<div><div>Complex post-traumatic stress disorder is a recent diagnosis with manifestations that differ from those of post-traumatic stress disorder. Persistent functional impairment is a new dimension specific to complex trauma. Some aspects of this diagnostic category which was adopted by the international classification of diseases eleventh revision are still being studied, for example, its prevalence across the world in many cultural situations where the exposure to traumatic events differ. Network analysis offers a new conceptualization of psychopathology by focusing on interactions between symptoms beyond the usual latent class approach. It makes it possible to statistically validate the international classification of diseases’ new diagnostic criteria by differentiating the manifestations of different pathologies such as intense stress exposure pathologies or borderline disorder that share symptoms. It also provides various insights into this disorder and allows us to observe sequences of appearance and evolution depending on age and type of event. While childhood trauma appears to be particularly associated with complex post-traumatic stress disorder, literature mainly highlights the long-term consequences of such childhood events in adulthood. The persistent functional impairment cluster is particularly important within complex trauma networks. This is one of the most important developmental consequences for survivors and reflects a reality perceived by clinicians. This extends to psychotherapy which turns out to be longer and more complex because of the insecurity of the relationship experienced by the traumatized person. Network analysis applied to complex trauma gives an understanding of the dynamics of the relationships between its multitude of symptoms. They can define intervention targets for mental health professionals. And they can enable coordinated multi-professional actions which is an important issue especially in multi-factorial situations such as child protection. This work explores the contributions of network analysis to the understanding of complex post-traumatic stress disorder. For this purpose, we outline the central concepts of complex trauma and its implications. In particular, the impact of recurring traumatic situations of an interpersonal nature on self-construction and the ability to create relationships. We exhibit the fundamental principles of the network approach and compare the contributions of older cross-sectional analyzes with those of longitudinal networks. Then, we provide an overview of the knowledge acquired through the application of network analysis to complex trauma, from childhood to adulthood. Finally, we discuss criticisms of this approach and propose reflections on the future of this statistical analysis method which is growing fast.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 6","pages":"Pages S32-S38"},"PeriodicalIF":1.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.encep.2025.05.006
Julie Rolling
Complex post-traumatic stress disorder (C-PTSD), caused by repeated traumatic events of interpersonal origin (such as physical or sexual violence, or war), leads to severe disorders of emotional regulation, self-perception and interpersonal relationships. Without early diagnosis and intervention, children and adolescents with C-PTSD are at risk of developing chronic mental disorders. Rapid therapeutic interventions are thus required in order to avoid the persistence of symptoms and at-risk behaviours altering the development and life trajectory of these young people. The aim of this article is to provide a state-of-the-art overview of existing therapeutic interventions aimed at professionals who screen, diagnose or care for children or adolescents with C-PTSD. The specific clinical and treatment profiles of these patients (e.g., stabilization, trauma treatment, promoting cognitive and psychological integration processes, self-compassion and engagement in interpersonal relations, family involvement) are detailed, in order to propose a diagnostic strategy and set out the various possibilities for comprehensive management based on adaptations of existing therapeutic protocols for these paediatric populations. Therapeutic, psychological and psychopharmacological approaches that are either validated or in development are presented, along with their current level of scientific evidence. This article highlights the importance of training French-speaking child and adolescent psychiatric professionals in these therapies, and of further developing research in this field.
{"title":"Panorama des thérapeutiques du trauma complexe chez l’enfant et l’adolescent","authors":"Julie Rolling","doi":"10.1016/j.encep.2025.05.006","DOIUrl":"10.1016/j.encep.2025.05.006","url":null,"abstract":"<div><div>Complex post-traumatic stress disorder (C-PTSD), caused by repeated traumatic events of interpersonal origin (such as physical or sexual violence, or war), leads to severe disorders of emotional regulation, self-perception and interpersonal relationships. Without early diagnosis and intervention, children and adolescents with C-PTSD are at risk of developing chronic mental disorders. Rapid therapeutic interventions are thus required in order to avoid the persistence of symptoms and at-risk behaviours altering the development and life trajectory of these young people. The aim of this article is to provide a state-of-the-art overview of existing therapeutic interventions aimed at professionals who screen, diagnose or care for children or adolescents with C-PTSD. The specific clinical and treatment profiles of these patients (e.g., stabilization, trauma treatment, promoting cognitive and psychological integration processes, self-compassion and engagement in interpersonal relations, family involvement) are detailed, in order to propose a diagnostic strategy and set out the various possibilities for comprehensive management based on adaptations of existing therapeutic protocols for these paediatric populations. Therapeutic, psychological and psychopharmacological approaches that are either validated or in development are presented, along with their current level of scientific evidence. This article highlights the importance of training French-speaking child and adolescent psychiatric professionals in these therapies, and of further developing research in this field.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 6","pages":"Pages S39-S49"},"PeriodicalIF":1.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}