内镜下脉冲氩等离子和球囊扩张术治疗难治性良性结直肠狭窄:一个病例系列。

IF 3 4区 医学 Q1 Medicine Translational gastroenterology and hepatology Pub Date : 2022-07-25 eCollection Date: 2022-01-01 DOI:10.21037/tgh.2020.03.06
Saad Emhmed Ali, Avinash Bhakta, Robert-Marlo Bautista, Ahmed Sherif, Wesam Frandah
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引用次数: 2

摘要

结肠和直肠的良性狭窄影响了相当一部分有潜在炎症疾病或最近接受过手术的患者。病因包括炎症性肠病(IBD)、术后缺血、吻合口狭窄、非甾体抗炎药(NSAIDs)和复杂性憩室炎。难治性结直肠狭窄是非常困难的,往往需要重复和不同的治疗方案。我们报告了一种使用氩气等离子体凝固(APC)和内镜下球囊扩张(EBD)作为一种安全有效的治疗顽固性良性结直肠狭窄的方法。4例有症状性良性结直肠狭窄的患者接受内镜治疗。在所有情况下(两名女性和两名男性;平均年龄62岁),内窥镜和x线检查显示明显狭窄(直径4- 13mm)。一例患者的狭窄继发于克罗恩病,另外三例患者的吻合口狭窄。采用1.5升/分钟、效应2、40瓦氩等离子体电灼和组织破坏的内镜下狭窄切开术,然后行EBD。所有患者均由一名高级内窥镜医师治疗。主要结果是脉冲氩等离子体和球囊扩张的内镜狭窄切开术的有效性和安全性。所有患者狭窄均得到缓解。无并发症报道。我们认为APC联合EBD是一种安全有效的治疗良性结肠狭窄的技术。
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Endoscopic stricturotomy with pulsed argon plasma and balloon dilation for refractory benign colorectal strictures: a case series.

Benign strictures of the colon and rectum affect a sizable portion of patients who have an underlying inflammatory disease or who have undergone recent surgery. Etiologies include inflammatory bowel disease (IBD), post-surgical ischemia, anastomotic strictures, non-steroidal anti-inflammatory drugs (NSAIDs), and complicated diverticulitis. Refractory colorectal strictures are very difficult to manage and often require repeated and different treatment options. We report a novel technique using argon plasma coagulation (APC) with endoscopic balloon dilation (EBD) as a safe and effective treatment modality for refractory benign colorectal strictures. Four patients with symptomatic benign colorectal strictures were referred for endoscopic treatment. In all cases (two females and two males; average age 62 years), the endoscopic and radiographic assessment showed significant strictures (diameter, 4-13 mm). The stricture was secondary to Crohn's disease in one patient and anastomotic strictures in the other three patients. Endoscopic stricturotomy through fulguration and tissue destruction using argon plasma at 1.5 liters/minute, effect 2, and 40 watts was performed, followed by EBD. All patients were treated by one advanced endoscopist. The primary outcomes were the efficiency and safety of endoscopic stricturotomy with pulsed argon plasma and balloon dilation. The resolution of stricture was achieved in all patients. No complications were reported. We believe that combined APC with EBD is a safe and effective technique in the treatment of benign colonic stricture.

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来源期刊
CiteScore
8.20
自引率
0.00%
发文量
1
期刊介绍: Translational Gastroenterology and Hepatology (Transl Gastroenterol Hepatol; TGH; Online ISSN 2415-1289) is an open-access, peer-reviewed online journal that focuses on cutting-edge findings in the field of translational research in gastroenterology and hepatology and provides current and practical information on diagnosis, prevention and clinical investigations of gastrointestinal, pancreas, gallbladder and hepatic diseases. Specific areas of interest include, but not limited to, multimodality therapy, biomarkers, imaging, biology, pathology, and technical advances related to gastrointestinal and hepatic diseases. Contributions pertinent to gastroenterology and hepatology are also included from related fields such as nutrition, surgery, public health, human genetics, basic sciences, education, sociology, and nursing.
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