艾滋病毒感染者(PLHIV)在 COVID-19 大流行中的营养问题:透视。

Q1 Biochemistry, Genetics and Molecular Biology Current Pharmacology Reports Pub Date : 2022-01-01 Epub Date: 2022-08-06 DOI:10.1007/s40495-022-00301-z
Fathima A S, Maxima Madhu, V Udaya Kumar, Sameer Dhingra, Nitesh Kumar, Sanjiv Singh, V Ravichandiran, Krishna Murti
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引用次数: 0

摘要

综述目的:本综述在 COVID-19 的背景下阐述了营养不良在 PLHIV(艾滋病病毒感染者)中的作用,并强调在后 COVID 时代需要补充营养、进行膳食干预和提供营养咨询。营养不良是艾滋病毒/艾滋病患者面临的最严峻挑战之一,因为它会削弱免疫系统,增加机会性感染的风险。在艾滋病毒(人体免疫缺陷病毒)感染者中,由于营养消耗减少、吸收不良、新陈代谢异常和抗逆转录病毒治疗,体重普遍下降。充足的营养是实现最佳免疫功能的必要条件,因此,食物疗法现在被认为是治疗艾滋病患者的重要辅助手段:营养干预,如使用膳食补充剂,有助于预防营养缺乏,降低营养不良的艾滋病患者的死亡风险。免疫力低下者感染 COVID-19 的风险非常高,营养不良会使感染风险增加数倍。营养教育和咨询等干预措施对于通过优化 HIV 患者的营养状况来改善他们的病情非常重要。在感染 COVID-19 的情况下,应确保艾滋病毒抗体阳性者继续获得足够和适当的援助,如营养和心理咨询。使用远程医疗来维持营养干预是有益的。为了满足他们的营养需求并尽量减少未来的困难,感染 COVID-19 的艾滋病毒携带者应接受专门的营养教育和咨询:
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Nutritional Aspects of People Living with HIV (PLHIV) Amidst COVID-19 Pandemic: an Insight.

Purpose of review: This review elaborates the role of malnutrition in PLHIV (people living with HIV) in the context of COVID-19 and emphasis the need of supplementation, dietary intervention, and nutritional counselling in the post-COVID era. One of the most critical challenges among HIV/AIDS patients is malnutrition since it weakens the immune system and increases risk to opportunistic infections. In HIV (human immunodeficiency virus) infection, weight loss is prevalent due to reduced nutritional consumption, malabsorption, abnormal metabolism, and antiretroviral therapy. Sufficient nutrition is required for optimal immune function, as a result, food therapy is now considered an important adjuvant in the treatment of HIV patients.

Recent findings: Nutritional intervention, such as the use of dietary supplements, can help to prevent nutrient deficiency, lowering the death risk among malnourished HIV population. Immunocompromised individuals are at very high risk for COVID-19 and malnutrition increases the risk of infection by multiple folds. Interventions, such as nutrition education and counselling are important, to improve the condition of HIV Patients by optimising their nutritional status.

Summary: A balanced diet should be one of the most important priorities in preventing PLHIV against the potentially deadly consequences of COVID-19. It is to be ensured that HIV-positive persons continue to get enough and appropriate assistance, such as nutrition and psychological counselling, in the context of COVID-19 infection. The use of telemedicine to maintain nutritional intervention can be beneficial. To meet their nutritional needs and minimise future difficulties, PLHIV infected with COVID-19 should get specialised nutritional education and counselling.

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来源期刊
Current Pharmacology Reports
Current Pharmacology Reports Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
9.30
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发文量
35
期刊介绍: Current Pharmacology Reports will: publish cutting-edge reviews on subjects pertinent to all aspects of pharmacology, including drug discovery and development.provide incisive, insightful, and balanced contributions from international leading experts.interest a wide readership of basic scientists and translational investigators in academia and in industry. The Current Pharmacology Reports journal accomplishes its goal by appointing international authorities to serve as Section Editors in key subject areas, such as: epigenetics and epigenomics, chemoinformatics and rational drug design and target discovery, drug delivery and biomaterial, pharmacogenomics and molecular targets and biomarkers, chemical/drug/molecular toxicology, absorption, distribution, metabolism and elimination (ADME), pharmacokinetics (PK) and pharmacodynamics (PD), Modeling & Simulation (M&S) and pharmacometrics, and other related topics in pharmacology including neurology/central nervous system (CNS), cardiovascular, metabolic diseases, cancer, among others. Section Editors for Current Pharmacology Reports select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided. This journal publishes on a bi-monthly schedule.Please submit here: https://www.editorialmanager.com/phar/default.aspx
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