{"title":"Ru(phen)32+-Ce(IV)体系快速流动注射化学发光法测定诺斯卡平","authors":"Behzad Rezaei, Ali Mokhtari, Taghi Khayamian","doi":"10.1002/adic.200790046","DOIUrl":null,"url":null,"abstract":"<p>A new flow injection chemiluminescence (CL) system was used for the determination of noscapine. This technique is based on the reduction effect of noscapine on the Ru(phen)<sub>3</sub><sup>3+</sup>, which is produced by reaction between Ru(phen)<sub>3</sub><sup>2+</sup> and acidic Ce(IV) solutions, and this rapid reduction produces strong CL. Calibration plots were linear over the range of 3.0×10<sup>-7</sup>-2.0×10<sup>-6</sup> mol L<sup>-1</sup> and 2.0×10<sup>-6</sup>-2.0×10<sup>-4</sup> mol L<sup>-1</sup>. The CL intensity was so high, that it is able to produce a detection limit of 6.6×10<sup>-8</sup> M noscapine (3σ). The relative standard deviation of 2.0×10<sup>-6</sup> M noscapine was 1.0% (n=10). The proposed method was successfully applied for the flow injection determination of noscapine in cough and Tonin syrup samples. The results of real sample analyses show good recovery percentages (97.3-102.4%). The minimum sampling rate was 100 samples per hour.</p>","PeriodicalId":8193,"journal":{"name":"Annali di chimica","volume":"97 8","pages":"605-614"},"PeriodicalIF":0.0000,"publicationDate":"2007-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/adic.200790046","citationCount":"4","resultStr":"{\"title\":\"A Simple and Rapid Flow-Injection Chemiluminescence Method for the Determination of Noscapine with Ru(phen)32+-Ce(IV) System\",\"authors\":\"Behzad Rezaei, Ali Mokhtari, Taghi Khayamian\",\"doi\":\"10.1002/adic.200790046\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A new flow injection chemiluminescence (CL) system was used for the determination of noscapine. This technique is based on the reduction effect of noscapine on the Ru(phen)<sub>3</sub><sup>3+</sup>, which is produced by reaction between Ru(phen)<sub>3</sub><sup>2+</sup> and acidic Ce(IV) solutions, and this rapid reduction produces strong CL. Calibration plots were linear over the range of 3.0×10<sup>-7</sup>-2.0×10<sup>-6</sup> mol L<sup>-1</sup> and 2.0×10<sup>-6</sup>-2.0×10<sup>-4</sup> mol L<sup>-1</sup>. The CL intensity was so high, that it is able to produce a detection limit of 6.6×10<sup>-8</sup> M noscapine (3σ). The relative standard deviation of 2.0×10<sup>-6</sup> M noscapine was 1.0% (n=10). The proposed method was successfully applied for the flow injection determination of noscapine in cough and Tonin syrup samples. The results of real sample analyses show good recovery percentages (97.3-102.4%). The minimum sampling rate was 100 samples per hour.</p>\",\"PeriodicalId\":8193,\"journal\":{\"name\":\"Annali di chimica\",\"volume\":\"97 8\",\"pages\":\"605-614\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-07-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1002/adic.200790046\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annali di chimica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/adic.200790046\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annali di chimica","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adic.200790046","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
摘要
采用一种新型流动注射化学发光系统测定诺斯卡平的含量。该技术是基于noscapine对Ru(phen)32+与酸性Ce(IV)溶液反应产生的Ru(phen)33+的还原作用，这种快速还原产生强CL。校正图在3.0×10-7-2.0×10-6 mol L-1和2.0×10-6-2.0×10-4 mol L-1范围内呈线性。CL强度很高，能产生6.6×10-8 M noscapine (3σ)的检出限。2.0×10-6 M noscapine的相对标准偏差为1.0% (n=10)。该方法成功地应用于止咳糖浆和补血糖浆样品中诺斯卡平的流动注射测定。实际样品分析结果表明，回收率为97.3 ~ 102.4%。最小采样率为每小时100个样本。
A Simple and Rapid Flow-Injection Chemiluminescence Method for the Determination of Noscapine with Ru(phen)32+-Ce(IV) System
A new flow injection chemiluminescence (CL) system was used for the determination of noscapine. This technique is based on the reduction effect of noscapine on the Ru(phen)33+, which is produced by reaction between Ru(phen)32+ and acidic Ce(IV) solutions, and this rapid reduction produces strong CL. Calibration plots were linear over the range of 3.0×10-7-2.0×10-6 mol L-1 and 2.0×10-6-2.0×10-4 mol L-1. The CL intensity was so high, that it is able to produce a detection limit of 6.6×10-8 M noscapine (3σ). The relative standard deviation of 2.0×10-6 M noscapine was 1.0% (n=10). The proposed method was successfully applied for the flow injection determination of noscapine in cough and Tonin syrup samples. The results of real sample analyses show good recovery percentages (97.3-102.4%). The minimum sampling rate was 100 samples per hour.
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