恶嗪和噻嗪支架作为有前景的药物化合物的绿色合成方法:综述。

IF 1.7 4区 化学 Q3 CHEMISTRY, ORGANIC Current organic synthesis Pub Date : 2024-01-01 DOI:10.2174/1570179420666230811092847
Abdulelah Aljuaid, Mamdouh Allahyani, Ahad Amer Alsaiari, Mazen Almehmadi, Abdulaziz Alsharif, Mohammad Asif
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引用次数: 0

摘要

医学研究人员密切关注恶嗪和噻嗪衍生物的绿色合成,因为它们为创造许多可能的生物活性化合物提供了先导分子。这篇综述提供了更多关于绿色合成的信息,这将非常有助于研究人员创造最有效、价格合理、具有临床意义的噻嗪和恶嗪衍生物,这些衍生物有望具有强大的药理作用。这导致了几种具有广泛有趣生物学功能的物质的鉴定。这篇文章的目的是研究用于产生恶嗪和噻嗪衍生物的许多绿色化学过程及其生物活性。我们预计,对恶嗪和噻嗪化学物质感兴趣的研究人员将发现这种材料是有用的。我们预计,寻找新的活性药物成分用于药物发现和进展的药物化学家将对这篇综述感兴趣。
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Green Synthetic Methods of Oxazine and Thiazine Scaffolds as Promising Medicinal Compounds: A Mini-review.

Medical researchers have paid close attention to the green synthesis of oxazine and thiazine derivatives since they provided a lead molecule for the creation of numerous possible bioactive compounds. This review provides more information on green synthesis, which will be very helpful to researchers in creating the most effective, affordable, and clinically significant thiazine and oxazine derivatives that are anticipated to have strong pharmacological effects. This has resulted in the identification of several substances with a wide range of intriguing biological functions. This article's goal is to examine the numerous green chemical processes used to create oxazine and thiazine derivatives and their biological activity. We anticipate that researchers interested in oxazine and thiazine chemicals will find this material to be useful. We anticipate that medicinal chemists looking for new active medicinal components for drug discovery and advance progress will find this review of considerable interest.

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来源期刊
Current organic synthesis
Current organic synthesis 化学-有机化学
CiteScore
3.40
自引率
5.60%
发文量
86
审稿时长
6-12 weeks
期刊介绍: Current Organic Synthesis publishes in-depth reviews, original research articles and letter/short communications on all areas of synthetic organic chemistry i.e. asymmetric synthesis, organometallic chemistry, novel synthetic approaches to complex organic molecules, carbohydrates, polymers, protein chemistry, DNA chemistry, supramolecular chemistry, molecular recognition and new synthetic methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by experts who are internationally known for their eminent research contributions. The journal is essential reading to all synthetic organic chemists. Current Organic Synthesis should prove to be of great interest to synthetic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic synthesis.
期刊最新文献
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