先天性心脏病的右心。

IF 3.8 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Current Heart Failure Reports Pub Date : 2023-12-01 Epub Date: 2023-09-29 DOI:10.1007/s11897-023-00629-7
Alexandra Arvanitaki, Gerhard Diller, George Giannakoulas
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引用次数: 0

摘要

综述目的:分析右心在不同类型先天性心脏病(CHD)中的病理生理重要性,总结当前的诊断模式,并讨论治疗方案。最近的研究结果:右心室(RV)在疾病进展和预后中起着关键作用,无论是作为肺下心室还是作为系统心室。容积和/或压力超负荷以及内在心肌疾病是RV重塑的主要因素。超声心动图和心脏磁共振成像是评估右心解剖、大小和功能的重要非侵入性方法。及时修复相关病变对于预防RV功能障碍至关重要。关于CHD相关RV功能障碍的常规药物治疗,几乎没有不确定的数据。心脏再同步治疗和心室辅助装置是晚期系统性RV衰竭患者的一种选择。右心疾病与冠心病的不良临床结果高度相关。研究应侧重于早期识别有风险的患者,并开发改善RV功能的医疗和介入治疗方法。
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The Right Heart in Congenital Heart Disease.

Purpose of review: To analyze the pathophysiologic importance of the right heart in different types of congenital heart disease (CHD), summarize current diagnostic modalities, and discuss treatment options.

Recent findings: The right ventricle (RV) plays a key role in disease progression and prognosis, either as the subpulmonary or as the systemic ventricle. Volume and/or pressure overload as well as intrinsic myocardial disease are the main factors for RV remodeling. Echocardiography and cardiac magnetic resonance imaging are important noninvasive modalities for assessing anatomy, size, and function of the right heart. Timely repair of related lesions is essential for preventing RV dysfunction. Few inconclusive data exist on conventional pharmacotherapy in CHD-related RV dysfunction. Cardiac resynchronization therapy and ventricular assist devices are an option in patients with advanced systemic RV failure. Right heart disease is highly related with adverse clinical outcomes in CHD. Research should focus on early identification of patients at risk and development of medical and interventional treatments that improve RV function.

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来源期刊
Current Heart Failure Reports
Current Heart Failure Reports Medicine-Emergency Medicine
CiteScore
5.30
自引率
0.00%
发文量
44
期刊介绍: This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of heart failure. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as investigative, pharmacologic, and nonpharmacologic therapies, pathophysiology, and prevention. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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