欺凌与首发精神病症状表现的关系。

Q3 Medicine Psychiatrike = Psychiatriki Pub Date : 2024-03-28 Epub Date: 2023-09-29 DOI:10.22365/jpsych.2023.021
Ioannis Kosteletos, Alexandros Hatzimanolis, Lida-Alkisti Xenaki, Irene Ralli, Stefanos Dimitrakopoulos, Ilias Vlahos, Mirijana Selakovic, Stefania Foteli, Rigas-Filippos Soldatos, Nikolaos Nianiakas, Konstantinos Kollias, Nikos Stefanis
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引用次数: 0

摘要

最近的多项研究表明,在参与精神分裂症谱系障碍病因的环境因素中,不良的心理创伤经历即使不是最显著的,也是特别显著的。与早期报告相比,青少年群体中欺凌的流行率急剧上升。这可能与最近通信技术的发展和社交媒体的使用有关,社交媒体扩大了实施欺凌的手段。本研究旨在调查首次发作精神病(FEP)患者的欺凌受害与精神病症状之间的关系,假设与没有欺凌史的患者相比,有欺凌病史的患者可能会增加精神病症状,并在正常治疗后出现更不利的早期轨迹。研究数据是从希腊普通人群中年龄在16岁至45岁之间(N=225)的男性和女性样本中收集的,他们在雅典首次发作精神病(FEP)研究中经历了FEP。使用回顾性欺凌问卷(RBQ)对欺凌行为进行评估。在基线和常规治疗4周后,使用阳性和阴性综合征量表(PANSS)的相应分量表对阳性和阴性精神病症状以及一般精神病理学进行评估。根据PANSS的基线和随访值以及Andreasen的症状标准评估临床缓解。方法上,Pearson卡方检验用于比较男性和女性的欺凌史,而线性和逻辑回归模型用于检查基线和4周随访时欺凌史与症状严重程度之间的相关性,以及欺凌史与缓解之间的相关性。在我们的FEP患者样本(N:225)中,欺凌史的发生率为51.4%(114/225)。在我们的研究参与者中,欺凌的频率在女性和男性中相同。根据分析结果,与没有欺凌史的患者相比,经历过欺凌的患者在基线时没有出现明显增加的精神病症状。此外,根据Andreasen的标准,欺凌与病情减轻无关。然而,在4周的随访中,经历过欺凌的患者的阴性症状显著增加(B=1.66;SE=0.70;p=0.018),PANSS总分增加(B=4.81;SE=2.34;p=0.041)。我们的研究结果强调了负面和整体症状的持续存在是欺凌对FEP发展的影响,并与支持在诊断和治疗过程中考虑欺凌史的研究一致。
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The relationship between bullying and symptom presentation in first-episode psychosis.

Multiple recent studies have indicated that adverse psycho-traumatic experiences are particularly significant, if not the most significant, among the environmental factors that participate in the aetiology of schizophrenic spectrum disorders. The prevalence of bullying in the adolescent population has increased dramatically compared to earlier reports. This may be related to the recent development of communication technology and the use of social media, which have expanded the means by which bullying can be practiced. The present study aims to investigate the association between bullying victimisation and psychotic symptoms in First-Episode Psychosis (FEP) patients, hypothesising that patients who have a bullying history may have increased psychotic symptoms and a more unfavourable early trajectory after treatment as usual compared to patients who do not have a bullying history. Research data were collected from a sample of men and women of the Greek general population aged between 16 and 45 (N=225) who experienced a FEP in the context of the Athens First-Episode Psychosis (FEP) Study. The assessment of bullying was performed using the Retrospective Bullying Questionnaire (RBQ). Assessment of positive and negative psychotic symptoms and general psychopathology was performed using the corresponding subscales of the Positive and Negative Syndrome Scale (PANSS) at baseline and after 4 weeks of treatment as usual. Clinical remission was assessed based on the baseline and follow-up values of the PANSS and on Andreasen's symptomatic criteria. Methodologically, Pearson's chi-square test was used to compare the history of bullying between men and women, while linear and logistic regression models were used to check the correlations between history of bullying and symptom severity at baseline and 4-week follow-up, as well as the correlation between history of bullying and remission. The prevalence of bullying history in our sample of patients (N:225) with a FEP was 51.4% (114/225). Bullying was recorded in our study participants with equal frequency in women and men. According to the analysis results, the patients who had experienced bullying did not present at baseline with significantly increased psychotic symptoms compared to the patients who did not have a history of bullying. In addition, bullying was not associated with reduced remission according to Andreasen's criteria. However, the patients who had experienced bullying were found to have significantly increased negative symptoms (B=1.66; SE=0.70; p=0.018) and increased PANSS total score (B=4.81; SE=2.34; p=0.041) at 4-week follow-up. Our results highlight the persistence of negative and overall symptoms as an impact of bullying on the development of the FEP and align with studies that support the consideration of a history of bullying during both the diagnostic and therapeutic processes.

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Psychiatrike = Psychiatriki
Psychiatrike = Psychiatriki Medicine-Medicine (all)
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