两只宠物大鼠(家鼠)上呼吸道肿瘤性阻塞引起的呼吸窘迫。

IF 1.3 3区 农林科学 Q2 VETERINARY SCIENCES Topics in companion animal medicine Pub Date : 2023-10-05 DOI:10.1016/j.tcam.2023.100823
Rachael Figueroa , Miranda J. Sadar , Chad Frank , Megan A. McCarthy , Michael K. Keel , David Sanchez-Migallon Guzman
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引用次数: 0

摘要

呼吸道疾病是宠物主人寻求兽医照顾他们的老鼠的主要原因之一。虽然慢性呼吸系统疾病复合体通常是宠物大鼠呼吸系统症状的原因,并且具有良好的特征,但文献中很少报道上呼吸道阻塞性疾病。本报告描述了两只宠物大鼠(家鼠),它们有几天的进行性呼吸体征史,对支持性治疗(包括抗生素、非甾体抗炎药以及液体和氧气支持)的反应最低。两例患者均在镇静状态下进行了X光检查。在第一个病例中,尽管发现了严重的噬气症,但无法确定临床症状的原因,部分原因是放射学定位不理想。在第二个病例中,发现颈部气管管腔变窄,气管壁软组织混浊增加。两只大鼠在镇静状态下都出现了衰退,导致第一只大鼠心肺骤停,第二只大鼠人道安乐死。尸检发现,第一例患者的口咽鳞状细胞癌起源于Zymbal腺,阻塞了喉部。第二例为管腔内气管肿块阻塞气道。这很可能是B细胞淋巴瘤或浆细胞肿瘤,尽管无法获得明确诊断。对于未来的此类病例,基于传染源的高流行率,使用抗菌药物、抗炎药和支持性护理对大鼠呼吸道疾病进行经验性治疗通常是合适的,然而,应考虑其他非传染性原因,如导致上呼吸道阻塞性疾病的肿瘤过程,并可能指示诊断成像。
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Respiratory Distress Caused by Neoplastic Upper Respiratory Tract Obstructions in 2 Pet Rats (Rattus Norvegicus Domestica)

Respiratory disease is one of the primary reasons for pet owners to seek veterinary attention for their rats. While chronic respiratory disease complex is most often responsible for respiratory signs in pet rats and is well characterized, upper respiratory obstructive disease has been rarely reported in the literature. This report describes 2 pet fancy rats (Rattus norvegicus domestica) presenting with a several day history of progressive respiratory signs that were minimally responsive to supportive therapies, including antibiotics, nonsteroidal anti-inflammatories, and fluid and oxygen support. Survey radiographs were performed under sedation in both cases. In the first case, no cause for the clinical signs could be identified, in part due to suboptimal radiographic positioning, although severe aerophagia was noted. In the second case, cervical tracheal luminal narrowing and increased soft tissue opacity along the walls of the trachea were identified. Both rats declined while under sedation, resulting in cardiopulmonary arrest in the first case and humane euthanasia in the second. On necropsy, the first case had a oropharyngeal squamous cell carcinoma originating from the Zymbal's gland, which was obstructing the larynx. The second case had an intra-luminal tracheal mass obstructing the airway. This was mostly likely B-cell lymphoma or a plasma cell tumor, although definitive diagnosis was unable to be obtained. For future such cases empiric management of respiratory disease in rats with antimicrobials, anti-inflammatories, and supportive care is often appropriate based on the high prevalence of infectious agents, however, other noninfectious causes should be considered, such as neoplastic processes leading to upper airway obstructive disease and diagnostic imaging may be indicated.

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来源期刊
Topics in companion animal medicine
Topics in companion animal medicine 农林科学-兽医学
CiteScore
2.30
自引率
0.00%
发文量
60
审稿时长
88 days
期刊介绍: Published quarterly, Topics in Companion Animal Medicine is a peer-reviewed veterinary scientific journal dedicated to providing practitioners with the most recent advances in companion animal medicine. The journal publishes high quality original clinical research focusing on important topics in companion animal medicine.
期刊最新文献
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