[新冠肺炎后综合征的肺部病理学]。

Q4 Medicine Arkhiv patologii Pub Date : 2023-01-01 DOI:10.17116/patol20238505152
S N Bugrov, I V Dvorakovskaya, B M Ariel
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引用次数: 0

摘要

严重急性呼吸系统综合征冠状病毒2型病毒(冠状病毒感染-CI)引起的感染伴随着感染后综合征(PS)的发展,其临床和病理解剖尚未得到足够的研究。这也适用于肺的形态功能变化,肺是PS最重要的组成部分之一。我们对20名22-75岁的男女患者的肺活检标本进行了组织学和细菌学研究。在许多患者中,PS的发展相对较晚,不早于CI急性临床症状发作后1年-1年4个月。PS肺部的结构变化表现为炎症反应,如间质性肺炎。大多数患者患有非特异性间质性肺炎,并伴有组织性间质性疾病,在某些情况下,还伴有肺结核特有的肉芽肿性反应。尽管如此,根据传统的细菌学和细菌学研究结果,肺纤维化的结核病因尚未得到证实。也许这是因为我们谈论的是一种隐性结核病感染,其病原体是结核分枝杆菌的L型。在x光检查中患有肺纤维化的PS患者应在肺结核学家或肺科医生的特别监督下。
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[Lung pathology in post-covid syndrome].

The clinic and pathological anatomy of the infection caused by the SARS-CoV-2 virus (coronavirus infection - CI) with the development of Post-Covid syndrome (PS) have not been studied enough. This also applies to morphofunctional changes in the lungs, one of the most important components of PS. We conducted a histological and bacterioscopic study of lung biopsy specimens in 20 patients of both sexes aged 22-75 years. In many patients, PS developed relatively late - not earlier than 1 year - 1 year 4 months after the onset of acute clinical symptoms of CI. Structural changes in the lungs in PS appear as an inflammatory reaction such as interstitial pneumonia. Most patients had nonspecific interstitial pneumonia with elements of organizing interstitial pneumonia, in some cases complicated by the presence of a specific granulomatous reaction, characteristic of pulmonary tuberculosis. Despite this, according to the results of traditional bacterioscopic and bacteriological studies, the tuberculous etiology of pulmonary fibrosis has not yet been confirmed. Perhaps this is due to the fact that we are talking about an inapparent tuberculosis infection, the causative agent of which is the L-form of Mycobacterium tuberculosis. Patients with PS who have pulmonary fibrosis on x-ray should be under the special supervision of a phthisiatrician or pulmonologist.

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来源期刊
Arkhiv patologii
Arkhiv patologii Medicine-Pathology and Forensic Medicine
CiteScore
0.90
自引率
0.00%
发文量
55
期刊介绍: The journal deals with original investigations on pressing problems of general pathology and pathologic anatomy, newest research methods, major issues of the theory and practice as well as problems of experimental, comparative and geographic pathology. To inform readers latest achievements of Russian and foreign medicine the journal regularly publishes editorial and survey articles, reviews of the most interesting Russian and foreign books on pathologic anatomy, new data on modern methods of investigation (histochemistry, electron microscopy, autoradiography, etc.), about problems of teaching, articles on the history of pathological anatomy development both in Russia and abroad.
期刊最新文献
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