Psilocybin治疗儿童不良经历幸存者心理困扰的潜力:Psilocybin使用的可接受性和潜在疗效证据。

IF 2.1 4区 医学 Q2 PSYCHOLOGY, CLINICAL Journal of psychoactive drugs Pub Date : 2024-11-01 Epub Date: 2023-10-10 DOI:10.1080/02791072.2023.2268640
Kiffer G Card, Ashmita Grewal, Kalysha Closson, Gina Martin, Laura Baracaldo, Sandra Allison, Daniel J Kruger, Zach Walsh
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引用次数: 0

摘要

有不良童年经历的幸存者有更高的心理痛苦风险。近年来,人们对迷幻药的新兴趣凸显了裸盖菇素对那些经历过童年逆境的人的治疗潜力。然而,娱乐性裸盖菇素的使用仍然是非法的,很难获得批准的治疗方法。这种使用为探索裸盖菇素对有不良童年经历的人的心理困扰的治疗潜力提供了机会。因此,我们进行了一项在线调查,以评估对裸盖菇素的兴趣、可接受性和使用体验。我们进一步探讨了在过去三个月内使用裸盖菇素的儿童不良经历问卷(ACEQ)评分与心理困扰之间的相关性是否较低。结果显示,人们对裸盖菇素的兴趣和可接受性很高,ACEQ评分没有差异。结果还表明,最近使用裸盖菇素的人,不良童年经历对心理困扰的影响较低(p = .019)。总之,这些发现表明,裸盖菇素疗法可能是潜在的可接受的,并可能有助于支持不良童年经历的幸存者,对那些有更严重童年逆境的人尤其有利。
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Therapeutic Potential of Psilocybin for Treating Psychological Distress among Survivors of Adverse Childhood Experiences: Evidence on Acceptability and Potential Efficacy of Psilocybin Use.

Survivors of adverse childhood experience are at elevated risk for psychological distress. In recent years, renewed interest in psychedelic medicine has highlighted the therapeutic potential of psilocybin for those who have experienced childhood adversity. However, recreational psilocybin use remains illegal and access to approved therapies is difficult. Such use provides an opportunity to explore the therapeutic potential of psilocybin for psychological distress among people with adverse childhood experiences. Therefore, we conducted an online survey to assess interest in, acceptability of, and experiences with psilocybin. We further explored whether the association between Adverse Childhood Experiences Questionnaire (ACEQ) scores and psychological distress was lower among those who had used psilocybin in the past three months. Results showed high levels of interest in and acceptability of psilocybin that did not differ across ACEQ scores. Results also showed that the effect of adverse childhood experiences on psychological distress was lower for people who had recently used psilocybin (p = .019). Taken together, these findings suggest that psilocybin therapy may be potentially acceptable and may feasibly help in supporting survivors of adverse childhood experiences with particularly strong benefits to those with more severe childhood adversity.

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来源期刊
CiteScore
5.30
自引率
7.10%
发文量
62
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