巨细胞动脉炎中的葡萄膜炎：7例观察病例的回顾性研究和文献复习。

IF 2.6 4区医学 Q2 OPHTHALMOLOGY Ocular Immunology and Inflammation Pub Date : 2024-10-01 Epub Date: 2023-10-10 DOI:10.1080/09273948.2023.2264383

William Gil, Laurent Kodjikian, Marc Andre, Indeep Kaur, Cécile Audrey Durel, Arnaud Hot, Maxime Fauter, Benjamin Chaigne, Perrine Smets, Maxime Samson, Pascal Seve

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引用次数: 0

摘要

目的：描述巨细胞动脉炎（GCA）患者葡萄膜炎的人口学和临床特征、治疗方法和演变。方法：进行全国性回顾性队列研究。纳入标准如下：符合2022年ACR/EULAR标准的GCA患者和经眼科医生证实的葡萄膜炎诊断。结果：包括7名女性。诊断为葡萄膜炎的中位年龄为71岁（64-84岁）。所有葡萄膜炎都是在活动性葡萄膜炎期间诊断出来的（5例在初次诊断时，2例在复发时）。所有葡萄膜炎均为急性葡萄膜炎（100%），主要为前部葡萄膜炎（86%）和双侧葡萄膜炎（71%）。肉芽肿特征不太常见（29%）。所有葡萄膜炎均采用局部和全身皮质类固醇治疗。在中位随访30（21-55）个月后，所有患者都获得了完全的眼科缓解，只有一例在2岁时复发年。GCA也完全缓解。结论：葡萄膜炎可显示GCA，其存在与GCA的疾病活动性有关。葡萄膜炎最常见的临床表现是急性和前部；使用局部和全身皮质类固醇，预后良好。

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Uveitis in Giant Cell Arteritis: A Retrospective Study of Seven Observational Cases and Literature Review.

Purpose: To describe the demographic and clinical characteristics of uveitis in patients with giant cell arteritis (GCA), their treatments, and evolution.

Methods: A national retrospective cohort study was performed. The inclusion criteria were as follows: patients with GCA fulfilling the 2022 ACR/EULAR criteria and a diagnostic of uveitis attested by an ophthalmologist.

Results: Seven women were included. The median age at diagnosis of uveitis was 71 years (64-84). All uveitis were diagnosed during active GCA (five at initial diagnosis, two at relapse). All uveitis were acute (100%), mostly anterior (86%) and bilateral (71%). Granulomatous features were less common (29%). All uveitis were treated with local and systemic corticosteroids. After a median follow-up of 30 (21-55) months, all patients achieved complete ophthalmic remission, with only one relapse at 2 years. GCA was also in complete remission.

Conclusions: Uveitis could reveal GCA, and its presence correlated with disease activity of GCA. The most frequent clinical presentation of uveitis was acute and anterior; using local and systemic corticosteroids, the prognosis was favorable.

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来源期刊

Ocular Immunology and Inflammation 医学-眼科学

CiteScore

6.20

自引率

15.20%

发文量

285

审稿时长

6-12 weeks

期刊介绍： Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.

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