改进孕妇流感疫苗接种的网络干预:成本效益分析。

IF 4.9 4区 医学 Q1 PARASITOLOGY Pathogens and Global Health Pub Date : 2024-03-01 Epub Date: 2023-10-16 DOI:10.1080/20477724.2023.2272109
Yingcheng Wang, Ginenus Fekadu, Joyce H S You
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引用次数: 0

摘要

据报道,一个提供疫苗信息和互动社交媒体的网站提高了孕妇流感疫苗的接种率。本研究旨在从美国医疗保健提供者的角度评估基于网络的孕妇流感疫苗接种干预的成本效益。一个为期一年的决策分析模型估计了一个假设孕妇队列的结果:(1)带有疫苗信息和互动社交媒体的网站(干预组),以及(2)常规护理(常规护理组)。主要指标包括流感感染、流感相关住院、死亡率、直接医疗费用和质量调整生命年(QALY)损失。在基本病例分析中,与常规护理组相比,干预组降低了成本(减少了28美元)、感染(减少了28/1000名孕妇)、住院治疗(减少了1.226/1000名孕妇)和死亡率(减少了0.0036/1000名孕产妇),并节省了0.000305个QALYs。在确定性敏感性分析中,干预措施对疫苗接种的相对改善和医疗系统中孕妇人数是两个影响因素。在10000次蒙特卡洛模拟中,99.5%的干预具有成本效益(愿意支付50000美元/QALY的阈值)。从美国医疗保健提供者的角度来看,一个提供疫苗信息和互动社交媒体的网站似乎可以降低直接医疗成本,并获得QALYs。
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Web-based intervention for improving influenza vaccination in pregnant women: a cost-effectiveness analysis.

A website with vaccine information and interactive social media was reported to improve maternal influenza vaccine uptake. This study aimed to evaluate cost-effectiveness of a web-based intervention on influenza vaccine uptake among pregnant women from the perspective of US healthcare providers. A one-year decision-analytic model estimated outcomes in a hypothetical cohort of pregnant women with: (1) website with vaccine information and interactive social media (intervention group), and (2) usual care (usual care group). Primary measures included influenza infection, influenza-related hospitalization, mortality, direct medical cost, and quality-adjusted life-year (QALY) loss. In base-case analysis, intervention group reduced cost (by USD28), infection (by 28 per 1,000 pregnant women), hospitalization (by 1.226 per 1,000 pregnant women), mortality (by 0.0036 per 1,000 pregnant women), and saved 0.000305 QALYs versus usual care group. Relative improvement of vaccine uptake by the intervention and number of pregnant women in the healthcare system were two influential factors identified in deterministic sensitivity analysis. The intervention was cost-effective in 99.5% of 10,000 Monte Carlo simulations (at willingness-to-pay threshold 50,000 USD/QALY). A website with vaccine information and interactive social media to promote influenza vaccination for pregnant women appears to reduce direct medical costs and gain QALYs from the perspective of US healthcare providers.

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来源期刊
Pathogens and Global Health
Pathogens and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-PARASITOLOGY
CiteScore
6.00
自引率
0.00%
发文量
60
审稿时长
6-12 weeks
期刊介绍: Pathogens and Global Health is a journal of infectious disease and public health that focuses on the translation of molecular, immunological, genomics and epidemiological knowledge into control measures for global health threat. The journal publishes original innovative research papers, reviews articles and interviews policy makers and opinion leaders on health subjects of international relevance. It provides a forum for scientific, ethical and political discussion of new innovative solutions for controlling and eradicating infectious diseases, with particular emphasis on those diseases affecting the poorest regions of the world.
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